2. Anti-infection
  3. Parasite
  4. Resorantel

Resorantel is an anthelmintic. Resorantel is used in the research of paramphistomiasis in cattle and sheep and has also been used for the research of G. aegypticus.

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Resorantel

Resorantel Estructura química

No. CAS : 20788-07-2

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Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
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Descripciòn

Resorantel is an anthelmintic[1]. Resorantel is used in the research of paramphistomiasis in cattle and sheep and has also been used for the research of G. aegypticus[2].

In Vivo

Resorantel (65 mg/kg, a single oral dose) possesses efficacy against paramphistomiasis in naturally infected sheep[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Five flocks of sheep in different villages of Haryana[1].
Dosage: 65 mg/kg.
Administration: A single oral dose.
Result: None of the treated sheep died of enteric paramphistomiasis. The clinical signs disappeared within 2 to 3 days of the treatment and their appetite and general condition improved. No ill effects of the drug were noticed. Of the untreated sheep, 35 % died with a range of 24-52 % in the different flocks. Many of the other untreated sheep continued to exhibit clinical signs of paramphistomiasis.
Peso molecular

308.13

Fòrmula

C13H10BrNO3
No. CAS
Appearance

Solid

Color

White to off-white

SMILES

O=C(NC1=CC=C(Br)C=C1)C2=C(O)C=CC=C2O
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvente y solubilidad
In Vitro: 

DMSO : 250 mg/mL (811.35 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.2454 mL 16.2269 mL 32.4538 mL
5 mM 0.6491 mL 3.2454 mL 6.4908 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Calculadora de molaridad

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Pureza y Documentación
Referencias

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.2454 mL 16.2269 mL 32.4538 mL 81.1346 mL
5 mM 0.6491 mL 3.2454 mL 6.4908 mL 16.2269 mL
10 mM 0.3245 mL 1.6227 mL 3.2454 mL 8.1135 mL
15 mM 0.2164 mL 1.0818 mL 2.1636 mL 5.4090 mL
20 mM 0.1623 mL 0.8113 mL 1.6227 mL 4.0567 mL
25 mM 0.1298 mL 0.6491 mL 1.2982 mL 3.2454 mL
30 mM 0.1082 mL 0.5409 mL 1.0818 mL 2.7045 mL
40 mM 0.0811 mL 0.4057 mL 0.8113 mL 2.0284 mL
50 mM 0.0649 mL 0.3245 mL 0.6491 mL 1.6227 mL
60 mM 0.0541 mL 0.2704 mL 0.5409 mL 1.3522 mL
80 mM 0.0406 mL 0.2028 mL 0.4057 mL 1.0142 mL
100 mM 0.0325 mL 0.1623 mL 0.3245 mL 0.8113 mL
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Resorantel20788-07-2ParasiteInhibitorinhibitorinhibit

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