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Results for "

Aquaporin

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Aquaporin (4) Apoptosis (1) Liposome (1) PROTAC Linkers (2)
By Research Areas:	Cancer (5) Cardiovascular Disease (1) Inflammation/Immunology (4) Neurological Disease (1)

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Targets Recommended: Aquaporin

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-W008574

TGN-020 Maximum Cited Publications 9 Publications Verification	PROTAC Linkers	Inflammation/Immunology Cancer
TGN-020 is a selective Aquaporin 4 (AQP4) inhibitor with an IC₅₀ of 3.1 μM . TGN-020 is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs .TGN-020 alleviates edema and inhibits glial scar formation after spinal cord compression injury in rats .

HY-W008574A

TGN-020 sodium Maximum Cited Publications 9 Publications Verification	PROTAC Linkers	Inflammation/Immunology Cancer
TGN-020 sodium is a selective Aquaporin 4 (AQP4) inhibitor with an IC₅₀ of 3.1 μM . TGN-020 sodium is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs . TGN-020 sodium alleviates edema and inhibits glial scar formation after spinal cord compression injury in rats .

HY-115460

AER-271	Aquaporin	Cardiovascular Disease Neurological Disease
AER-271, a phosphonate proagent derivative of AER-270, is an *aquaporin-4* (AQP4) inhibitor for the research of acute ischemic stroke .

HY-N6016

Bacopaside II 1 Publications Verification	Apoptosis	Cancer
Bacopaside II, an extract from the medicinal herb Bacopa monnieri, blocks the Aquaporin-1 (AQP1) water channel and impairs migration of cells that express AQP1. Bacopaside II induces cell cycle arrest and apoptosis .

HY-126074

Z433927330	Aquaporin	Others
Z433927330 is a potent and selective inhibitor of Aquaporin-7 (AQP7), less potently inhibits AQP3 and AQPs9, with IC₅₀s of ~0.2 µM, ~0.7 µM and ~1.1 µM for mAQP7, mAQP3 and mAQP9, respectively .

HY-126073

DFP00173 3 Publications Verification	Aquaporin	Inflammation/Immunology Cancer
DFP00173 is a potent and selective aquaporin-3 (AQP3) inhibitor. DFP00173 inhibits mouse and human AQP3 with an IC₅₀ of ∼0.1-0.4 μM. DFP00173 is selective for AQP3 over the homologous AQP isoforms AQP7 and AQP9 .

HY-142980

Dioleoylphosphatidylglycerol DOPG	Liposome	Inflammation/Immunology
Dioleoylphosphatidylglycerol (DOPG) is a naturally occurring phospholipid that can be produced by the combined action of aquaporin 3 (AQP3) and phospholipase D2 (PLD2). Dioleoylphosphatidylglycerol inhibits macrophage inflammatory mediator production in response to heat shock protein B4 (HSPB4) activation of toll-like receptor 2 (TLR2) .

HY-157979

AQP3-IN-1

Aquaporin Cancer

AQP3-IN-1 (compounds 3) is an AQP3 inhibitor with a IC₅₀ value of 8.91 μM. AQP3-IN-1 inhibits cell proliferation of melanoma cells .

AQP3-IN-1	Aquaporin	Cancer
AQP3-IN-1 (compounds 3) is an AQP3 inhibitor with a IC₅₀ value of 8.91 μM. AQP3-IN-1 inhibits cell proliferation of melanoma cells .

Cat. No.	Product Name	Type

HY-142980

Dioleoylphosphatidylglycerol DOPG	Drug Delivery
Dioleoylphosphatidylglycerol (DOPG) is a naturally occurring phospholipid that can be produced by the combined action of aquaporin 3 (AQP3) and phospholipase D2 (PLD2). Dioleoylphosphatidylglycerol inhibits macrophage inflammatory mediator production in response to heat shock protein B4 (HSPB4) activation of toll-like receptor 2 (TLR2) .

Cat. No.	Product Name	Target	Research Area

HY-P5513

Aquaporin-2 (254-267), pSER261, human	Peptides	Others
Aquaporin-2 (254-267), pSER261, human is a biological active peptide. (This peptide is a fragment of the human aquaporin-2 (AQP2) phosphorylated at Ser261. Protein phosphorylation plays a key role in vasopressin signaling in renal-collecting duct. Phosphorylation at several AQP2 residues including Ser256 and Ser261, is altered in response to vasopressin. It is possible that both sites are involved in vasopressin-dependent AQP2 trafficking.)

Bacopaside II 1 Publications Verification	Triterpenes Structural Classification Classification of Application Fields Terpenoids Source classification Scrophulariaceae Plants Disease Research Fields Bacopa monnieri (Linn.) Wettst. Cancer	Apoptosis
Bacopaside II, an extract from the medicinal herb Bacopa monnieri, blocks the Aquaporin-1 (AQP1) water channel and impairs migration of cells that express AQP1. Bacopaside II induces cell cycle arrest and apoptosis .

Species:	Human (5) Mouse (3) Rat (1)
Tag:	SUMO (3) His (7) Tag Free (1) GST (1)
Source:	E. coli Cell-free (6) E. coli (3)

Cat. No.	Compare	Product Name	Species	Source

HY-P72086

	AQP1 Protein, Human (GST) AQP 1; AQP CHIP; AQP-1; AQP1; AQP1_HUMAN; Aquaporin 1 channel-forming integral protein; 28kDa; CO blood group; ; Aquaporin 1 Colton blood group; ; Aquaporin CHIP; Aquaporin-1; Aquaporin-CHIP; Aquaporin1; Channel forming integral protein 28kDa; Channel like integral membrane protein 28 kDa; CHIP 28; CHIP28; CO;	Human	E. coli
	The AQP1 protein forms water-specific channels that allow water to cross red blood cells and renal proximal tubule membranes. AQP1 Protein, Human (GST) is the recombinant human-derived AQP1 protein, expressed by E. coli , with N-GST labeled tag. The total length of AQP1 Protein, Human (GST) is 50 a.a., with molecular weight of ~31 kDa.

HY-P700377

	Aquaporin-1/AQP1 Protein, Human (Cell-Free, His-SUMO) AQP CHIP; AQP-1; AQP1; AQP1_HUMAN; Aquaporin 1 channel-forming integral protein; 28kDa; CO blood group; ; Aquaporin 1 Colton blood group; ; Aquaporin CHIP; Aquaporin-1; Aquaporin-CHIP; Aquaporin1; Channel forming integral protein 28kDa; Channel like integral membrane protein 28 kDa; CHIP 28; CHIP28; CO; Colton blood group; Growth factor induced delayed early response protein; MGC26324; Urine water channel; Water channel protein CHIP 29; Water channel protein CHIP29; Water channel protein for red blood cells and kidney proximal tubule	Human	E. coli Cell-free
	The AQP1 protein forms water-specific channels that allow water to cross red blood cells and renal proximal tubule membranes. Aquaporin-1/AQP1 Protein, Human (Cell-Free, His-SUMO) is the recombinant human-derived Aquaporin-1/AQP1 protein, expressed by E. coli Cell-free , with N-SUMO, N-6*His labeled tag. The total length of Aquaporin-1/AQP1 Protein, Human (Cell-Free, His-SUMO) is 268 a.a., with molecular weight of 41.3 kDa.

HY-P72085

	AQP1 Protein, Human (His-SUMO) AQP 1; AQP CHIP; AQP-1; AQP1; AQP1_HUMAN; Aquaporin 1 channel-forming integral protein; 28kDa; CO blood group; ; Aquaporin 1 Colton blood group; ; Aquaporin CHIP; Aquaporin-1; Aquaporin-CHIP; Aquaporin1; Channel forming integral protein 28kDa; Channel like integral membrane protein 28 kDa; CHIP 28; CHIP28; CO; Colton blood group; Growth factor induced delayed early response protein; MGC26324; Urine water channel; Water channel protein CHIP 29; Water channel protein CHIP29; Water channel protein for red blood cells and kidney proximal tubule	Human	E. coli
	The AQP1 protein forms water-specific channels that allow water to cross red blood cells and renal proximal tubule membranes. AQP1 Protein, Human (His-SUMO) is the recombinant human-derived AQP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag. The total length of AQP1 Protein, Human (His-SUMO) is 50 a.a., with molecular weight of ~21.6 kDa.

HY-P702217

	AQP5 Protein, Human (Cell-Free, His) Aquaporin-5; AQP-5	Human	E. coli Cell-free
	The AQP5 protein forms water-specific channels that are essential for fluid secretion in salivary glands. AQP5 Protein, Human (Cell-Free, His) is the recombinant human-derived AQP5 protein, expressed by E. coli Cell-free , with N-10*His labeled tag. The total length of AQP5 Protein, Human (Cell-Free, His) is 265 a.a., with molecular weight of 31.1 kDa.

HY-P702213

	AQP2 Protein, Mouse (Cell-Free, His) Aquaporin-2; ADH water channel; Aquaporin-CD; AQP-CD; Collecting duct water channel protein; WCH-CD; Water channel protein for renal collecting duct	Mouse	E. coli Cell-free
	AQP2 is a homotetrameric protein that plays a key role in renal water homeostasis. It acts as a water-specific channel, facilitating the movement of water across the plasma membrane of the renal collecting duct. AQP2 Protein, Mouse (Cell-Free, His) is the recombinant mouse-derived AQP2 protein, expressed by E. coli Cell-free , with N-10*His labeled tag. The total length of AQP2 Protein, Mouse (Cell-Free, His) is 271 a.a., with molecular weight of 30.5 kDa.

HY-P702214

	AQP2 Protein, Rat (Cell-Free, His) Aquaporin-2; ADH water channel; Aquaporin-CD; AQP-CD; Collecting duct water channel protein; WCH-CD; Water channel protein for renal collecting duct	Rat	E. coli Cell-free
	AQP2 Protein, a water-specific channel, imparts high water permeability to renal collecting duct plasma membranes, facilitating water movement along osmotic gradients. Crucial for renal water homeostasis, AQP2 significantly regulates water reabsorption in the kidneys. Existing as a homotetramer, it is a key component in selectively transporting water through renal tissues. AQP2 Protein, Rat (Cell-Free, His) is the recombinant rat-derived AQP2 protein, expressed by E. coli Cell-free , with N-10*His labeled tag. The total length of AQP2 Protein, Rat (Cell-Free, His) is 271 a.a., with molecular weight of 30.4 kDa.

HY-P72087

	AQP4 Protein, Human (His-SUMO) AQP 4; AQP-4; AQP4; AQP4_HUMAN; Aquaporin type 4; Aquaporin-4; Aquaporin4; HMIWC 2; HMIWC2; Mercurial insensitive water channel; Mercurial-insensitive water channel; MGC22454; MIWC; WCH 4; WCH4	Human	E. coli
	The AQP4 protein forms water-specific channels and is involved in brain water balance and solute transport. AQP4 Protein, Human (His-SUMO) is the recombinant human-derived AQP4 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag. The total length of AQP4 Protein, Human (His-SUMO) is 71 a.a., with molecular weight of ~27 kDa.

HY-P702215

	AQP4 Protein, Mouse (Cell-Free) Aquaporin-4; Mercurial-insensitive water channel; MIWC; WCH4	Mouse	E. coli Cell-free
	The AQP4 protein forms water-specific channels that are critical for brain water homeostasis and lymphoid solute transport. It regulates water exchange at the blood-brain interface, promoting the influx of cerebrospinal fluid into the brain and the drainage of interstitial fluid. AQP4 Protein, Mouse (Cell-Free) is the recombinant mouse-derived AQP4 protein, expressed by E. coli Cell-free , with tag free. The total length of AQP4 Protein, Mouse (Cell-Free) is 323 a.a., with molecular weight of 34.8 kDa.

HY-P702216

	AQP4 Protein, Mouse (Cell-Free, His) Aquaporin-4; Mercurial-insensitive water channel; MIWC; WCH4	Mouse	E. coli Cell-free
	The AQP4 protein forms water-specific channels that are critical for brain water homeostasis and lymphoid solute transport. It regulates water exchange at the blood-brain interface, promoting the influx of cerebrospinal fluid into the brain and the drainage of interstitial fluid. AQP4 Protein, Mouse (Cell-Free, His) is the recombinant mouse-derived AQP4 protein, expressed by E. coli Cell-free , with N-10*His labeled tag. The total length of AQP4 Protein, Mouse (Cell-Free, His) is 323 a.a., with molecular weight of 40.5 kDa.


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Cat. No.	Product Name	Application	Reactivity

HY-P81136

Aquaporin 5 Antibody Aquaporin 5; AQP5; AQP 5; AQP-5; AQP5_HUMAN; Aquaporin-5.	WB; ELISA; IHC-P; IHC-F; Flow-Cyt; IF	Human, Mouse, Rat(predicted: Dog, Pig, Cow, Horse, Sheep)
Aquaporin 5 Antibody is an unconjugated, approximately 29 kDa, rabbit-derived, anti-Aquaporin 5 polyclonal antibody. Aquaporin 5 Antibody can be used for: WB, ELISA, IHC-P, IHC-F, Flow-Cyt, IF expriments in human, mouse, rat, and predicted: dog, pig, cow, horse, sheep background without labeling.

HY-P83459A

Aquaporin 4 Antibody Aquaporin 4; WCH4; Mercurial-insensitive water channel; MIWC; AQP 4; AQP4; Aquaporin4; HMIWC 2; HMIWC2; Mercurial insensitive water channel; MGC22454; MIWC; AQP4_HUMAN; Aquaporin-4; AQP-4.	WB, IHC-P, IHC-F, Flow-Cyt, IF	Human, Mouse, Rat, Pig, Cow, Rabbit, Sheep

HY-P81400

Aquaporin 3 Antibody (YA1145)

Aquaporin 3; AQP-3; Aquaglyceroporin-3; AQP3
IHC-P Human
HY-P82397

Aquaporin 2 Antibody (YA2142)

AQP-CD; WCH-CD
WB, IHC-P, IP Human
HY-P83459

Aquaporin 4 Antibody (YA3204)

AQP4; Aquaporin-4; AQP-4; Mercurial-insensitive water channel; MIWC; WCH4
IHC-P Human, Rat
HY-P81404

Aquaporin 1 Antibody (YA1149)

AQP1; CHIP28; Aquaporin-1; AQP-1; Aquaporin-CHIP; Urine water channel; Water channel protein for red blood cells and kidney proximal tubule
IHC-P Human

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Aquaporin

Inhibitors & Agonists

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