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DFP00173 

Cat. No.: HY-126073
Handling Instructions

DFP00173 is a potent and selective aquaporin-3 (AQP3) inhibitor. DFP00173 inhibits mouse and human AQP3 with an IC50 of ∼0.1-0.4 μM. DFP00173 is selective for AQP3 over the homologous AQP isoforms AQP7 and AQP9.

For research use only. We do not sell to patients.

DFP00173 Chemical Structure

DFP00173 Chemical Structure

CAS No. : 672286-03-2

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Based on 1 publication(s) in Google Scholar

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Description

DFP00173 is a potent and selective aquaporin-3 (AQP3) inhibitor. DFP00173 inhibits mouse and human AQP3 with an IC50 of ∼0.1-0.4 μM. DFP00173 is selective for AQP3 over the homologous AQP isoforms AQP7 and AQP9[1].

In Vitro

DFP00173 inhibits the glycerol permeability of human erythrocytes with an IC50 of ~0.2 µM[1].

Molecular Weight

332.16

Formula

C₁₁H₇Cl₂N₃O₃S

CAS No.

672286-03-2

SMILES

O=C(NC1=CSC([N+]([O-])=O)=C1)NC2=C(Cl)C=CC=C2Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
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Keywords:

DFP00173DFP 00173DFP-00173OthershomologousAQPisoformsglycerolpermeabilityselectivehumanerythrocytesInhibitorinhibitorinhibit

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