672286-03-2
672286-03-2
Chemical Structure
DFP00173
- CAS No.: 672286-03-2
- Formula:C11H7Cl2N3O3S
- Molecular Weight:332.16
IUPAC Name: 1-(2,6-dichlorophenyl)-3-(5-nitrothiophen-3-yl)urea
InChIKey: AATXXTHMITUAOJ-UHFFFAOYSA-N
SMILES: O=C(NC1=CSC([N+]([O-])=O)=C1)NC2=C(Cl)C=CC=C2Cl
Biological Activity: DFP00173 is a potent and selective aquaporin-3 (AQP3) inhibitor. DFP00173 inhibits mouse and human AQP3 with an IC50 of ～0.1-0.4 μM. DFP00173 is selective for AQP3 over the homologous AQP isoforms AQP7 and AQP9[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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DFP00173 | 99.46% | DFP00173 is a potent and selective aquaporin-3 (AQP3) inhibitor. DFP00173 inhibits mouse and human AQP3 with an IC50 of ～0.1-0.4 μM. DFP00173 is selective for AQP3 over the homologous AQP isoforms AQP7 and AQP9. | ||||||||||||||||||||
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