MMV665852
Based on 1 Customer Validation
MMV665852 is an antischistosomal agent that inhibits worm viability in vitro. MMV665852 reduces worm burden in mice infected with Schistosoma mansoni.
For research use only. We do not sell to patients.
- CAS No.: 4300-43-0
- Formula: C13H8Cl4N2O
- Molecular Weight:350.03
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| Huh-7 | CC50 |
20.22 μM
Compound: GNF-Pf-2903
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NOVARTIS: Cytotoxicity against human hepatocellular carcinoma cell line (Huh7)
NOVARTIS: Cytotoxicity against human hepatocellular carcinoma cell line (Huh7)
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[PMID: 18579783] |
| MRC5 | IC50 |
>32 μM
Compound: MMV665852
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MMV: Cytotoxicity against human fibroblasts (MRC-5) cells.
MMV: Cytotoxicity against human fibroblasts (MRC-5) cells.
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10.6019/CHEMBL2028040 |
| Vero C1008 | CC50 |
>33 μM
Compound: MMV665852
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Toxicity CC50 against VERO-E6 cells determined at 48 hours by high content imaging (same conditions as 2_LEY without exposure to 0.01 MOI SARS CoV-2 virus)
Toxicity CC50 against VERO-E6 cells determined at 48 hours by high content imaging (same conditions as 2_LEY without exposure to 0.01 MOI SARS CoV-2 virus)
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10.6019/CHEMBL4495565 |
| Vero C1008 | IC50 |
3.97 μM
Compound: MMV665852
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Determination of IC50 values for inhibition of SARS-CoV-2 induced cytotoxicity of VERO-E6 cells after 48 hours exposure to 0.01 MOI SARS CoV-2 virus by high content imaging
Determination of IC50 values for inhibition of SARS-CoV-2 induced cytotoxicity of VERO-E6 cells after 48 hours exposure to 0.01 MOI SARS CoV-2 virus by high content imaging
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10.6019/CHEMBL4495565 |
Chemical Information
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CAS No. 4300-43-0
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Molecular Weight 350.03
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Formula C13H8Cl4N2O
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SMILES
O=C(NC1=CC=C(C(Cl)=C1)Cl)NC2=CC=C(C(Cl)=C2)Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
MMV665852 Related Classifications
HY-124018 Related Classifications
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