2. Membrane Transporter/Ion Channel
  3. Aquaporin
  4. AQP3-IN-1

AQP3-IN-1 (compounds 3) is an AQP3 inhibitor with a IC50 value of 8.91 μM. AQP3-IN-1 inhibits cell proliferation of melanoma cells.

For research use only. We do not sell to patients.

AQP3-IN-1 Chemical Structure

AQP3-IN-1 Chemical Structure

CAS No. : 198711-19-2

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AQP3-IN-1 Related Antibodies

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Description

AQP3-IN-1 (compounds 3) is an AQP3 inhibitor with a IC50 value of 8.91 μM. AQP3-IN-1 inhibits cell proliferation of melanoma cells[1].

IC50 & Target

AQP3

8.91 μM (IC50)

In Vitro

AQP3-IN-1 (compound 3) (5 μM, 30 min) inhibits cell permeability and glycerol permeability of erythrocytes overexpressing AQP3, but does not affect their water permeability[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

AQP3-IN-1 Related Antibodies

Cell Viability Assay[1]

Cell Line: MNT-1, A375 and HEK-293T
Concentration: 2.5-10 μM
Incubation Time: 24 h
Result: Had no toxic effect on MNT-1 and A375 cells and did not affect cell viability.

Cell Migration Assay [1]

Cell Line: MNT-1, A375
Concentration: 5 μM
Incubation Time: 0, 9, 24 h
Result: Inhibited melanoma cell adhesion, proliferation, and migration.
Molecular Weight

437.08

Formula

C11H9AuCl2N2
CAS No.
SMILES

[Cl-][Au+3]1([C-]2=C(NC3=[N]1C=CC=C3)C=CC=C2)[Cl-]
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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AQP3-IN-1 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

AQP3-IN-1198711-19-2AquaporinAQPPeroxiporin activityMelanoma cellsAnticancerMNT-1A375AQP3Inhibitorinhibitorinhibit

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