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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
33 Results for "
B1473
" in MedChemExpress (MCE) Product Catalog:
Products (33)
33 Results for "B1473" in MCE Product Catalog:
41
41 Publications Verification
Synonyms: 5-Hydroxytryptamine; 5-HT
Category:
Target:
41
41 Publications Verification
Synonyms: 5-Hydroxytryptamine hydrochloride; 5-HT hydrochloride
Category:
Target:
2
2 Cited Publications
Cat. No.: HY-B0168A
CAS No.: 101152-94-7
Target:
Research Areas:
Milnacipran hydrochloride is an orally active Serotonin (HY-B1473A) and Norepinephrine (HY-13715) reuptake inhibitor. Milnacipran hydrochloride inhibits monoamine transporters, especially the norepinephrine transporter and the serotonin transporter (Ki values of 31 and 8.5 nM, respectively). Milnacipran hydrochloride inhibits pERK1/2 activation. Milnacipran hydrochloride has antidepressant, anxiolytic and analgesic properties. Milnacipran hydrochloride inhibits biting behavior in mice. Milnacipran hydrochloride can be used in the study of major depressive disorder, anxiety disorders, and neuropathic pain (e.g., fibromyalgia) .
2
2 Cited Publications
Cat. No.: HY-B0168
CAS No.: 92623-85-3
Target:
Research Areas:
Milnacipran is an orally active Serotonin (HY-B1473A) and Norepinephrine (HY-13715) reuptake inhibitor. Milnacipran inhibits monoamine transporters, especially the norepinephrine transporter and the serotonin transporter (Ki values of 31 and 8.5 nM, respectively). Milnacipran inhibits pERK1/2 activation. Milnacipran has antidepressant, anxiolytic and analgesic properties. Milnacipran inhibits biting behavior in mice. Milnacipran can be used in the study of major depressive disorder, anxiety disorders, and neuropathic pain (e.g., fibromyalgia) .
1
1 Cited Publications
Cat. No.: HY-B1473AS
CAS No.: 58264-95-2
Synonyms: 5-Hydroxytryptamine-d4; 5-HT-d4
1
1 Cited Publications
Cat. No.: HY-B1473S
CAS No.: 2469263-61-2
Synonyms: 5-Hydroxytryptamine-d4 hydrochloride; 5-HT-d4 hydrochloride
1
1 Cited Publications
Synonyms: 5-Propargyltryptamide formic
Target:
Research Areas:
5-PT (5-Propargyltryptamide) formic is an alkyne-functionalized 5-HT (HY-B1473A) derivative and serotonylation substrate, taken up by living cells. 5-PT formic conjugated to a biotin enables identification of serotonylated proteins via copper-click chemistry and mass spectrometry. 5-PT formic labels and isolates serotonylated cells in alveolar epithelial cells for proteomic analysis. 5-PT formic can be used for the research of bronchopulmonary dysplasia .
Synonyms: 5-Hydroxytryptamine hydrochloride (Standard); 5-HT hydrochloride (Standard)
Category:
Cat. No.: HY-B1473S2
CAS No.: 1269486-67-0
Synonyms: 5-Hydroxytryptamine-13C,D4; 5-HT-13C,D4
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Naftidrofuryl oxalate (Nafronyl oxalate salt) is an orally active 5-HT2 receptor antagonist. Naftidrofuryl oxalate selectively blocks vascular and platelet 5-HT2 receptors, inhibiting Serotonin (HY-B1473A)-induced vasoconstriction, platelet aggregation, and vascular smooth muscle cell proliferation. Naftidrofuryl oxalate can be used for the research of intermittent claudication, peripheral occlusive arterial disease, and critical limb ischaemia .
Synonyms: EP-A-501322
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Research Areas:
RS 23597-190 (EP-A-501322) is a high affinity and selective 5-HT4 receptor antagonist. RS 23597-190 inhibits Serotonin (HY-B1473A)-induced tachycardia. RS 23597-190 significantly inhibits superoxide production in high glucose .
Cat. No.: HY-W017158
CAS No.: 495-78-3
Category:
Monophenols Ketones, Aldehydes, Acids Metabolic Disease Phenols Endogenous metabolite Disease Research Fields
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Cat. No.: HY-156562
CAS No.: 92085-05-7
Synonyms: 5-Propargyltryptamide
Target:
Research Areas:
5-PT (5-Propargyltryptamide) is an alkyne-functionalized 5-HT (HY-B1473A) derivative and serotonylation substrate, taken up by living cells. 5-PT conjugated to a biotin enables identification of serotonylated proteins via copper-click chemistry and mass spectrometry. 5-PT labels and isolates serotonylated cells in alveolar epithelial cells for proteomic analysis. 5-PT can be used for the research of bronchopulmonary dysplasia .
Synonyms: (1R,2S)-Milnacipran; F2696
Research Areas:
Dextromilnacipran ((1R,2S)-Milnacipran; F2696) is an orally active Serotonin (HY-B1473A)/Noradrenaline (HY-13715) transporter inhibitor. Dextromilnacipran inhibits Serotonin and Noradrenaline reuptake. Dextromilnacipran can be used for the research of depression, fibromyalgia .
Research Areas:
Metaldehyde is an orally active molluscicide. Metaldehyde acts as a feeding inhibitor. Metaldehyde disrupts the feeding cycle, impairs righting ability, delays fecal excretion, induces toxic symptoms in slugs, reduces the concentrations of neurotransmitters (Noradrenaline, 5-HT (HY-B1473A)) in the mouse brain, and induces lethal clonic-tonic convulsions in mice .
Cat. No.: HY-15386
CAS No.: 73815-11-9
Synonyms: MD 780515
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Research Areas:
Cimoxatone (MD 780515) is a reversible, selectively and orally active type A monoamine oxidase (MAO-A) inhibitor. Cimoxatone enhances the anorectic action of Serotonin (HY-B1473A) .
Cat. No.: HY-W017158R
CAS No.: 495-78-3
Cat. No.: HY-14794S
CAS No.: 1127352-73-1
Synonyms: (1R,2S)-Milnacipran-d6; F2696-d6
Cat. No.: HY-B0168S
CAS No.: 1217774-40-7
Cat. No.: HY-123199
CAS No.: 98409-42-8
Synonyms: SABA
Target:
Research Areas:
Serotonin azidobenzamidine is an arylazido derivative of 5-hydroxytryptamine (HY-B1473A). Serotonin azidobenzamide competitively inhibits [3H]5-hydroxytryptamine uptake by rat cortical synaptosomes in the dark with a Ki of 130 nM .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
