2. Neuronal Signaling
  3. Monoamine Oxidase
  4. Cimoxatone

Cimoxatone (MD 780515) is a reversible, selectively and orally active type A monoamine oxidase (MAO-A) inhibitor. Cimoxatone enhances the anorectic action of Serotonin (HY-B1473A).

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Cimoxatone Chemical Structure

Cimoxatone Chemical Structure

CAS No. : 73815-11-9

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Cimoxatone Related Antibodies

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Description

Cimoxatone (MD 780515) is a reversible, selectively and orally active type A monoamine oxidase (MAO-A) inhibitor. Cimoxatone enhances the anorectic action of Serotonin (HY-B1473A)[1].

IC50 & Target[1]

MAO-A

 

In Vivo

Cimoxatone (20 mg/kg; p.o.) enhances the anorectic action of 5-HT (1 mg/kg; s.c.) in rats[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: 250-300 g, Adult male Wistar rats[1]
Dosage: 20 mg/kg
Administration: P.o.
Result: Significiantly reduced sucrose intake induced by 1 mg/kg 5-HT or its vehicle injected 2 and 24 h later, significantly enhanced the anorectic action of 5-HT at 2 h but not at 24 h.
Molecular Weight

338.36

Formula

C19H18N2O4
CAS No.
SMILES

N#CC1=CC=CC(COC2=CC=C(N3C(OC(COC)C3)=O)C=C2)=C1
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Purity & Documentation
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Cimoxatone Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Cimoxatone73815-11-9MD 780515MD780515MD-780515Monoamine OxidaseMAOorally active5-HTsucrose intakeanorecticInhibitorinhibitorinhibit

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