Serotonin-d4 hydrochloride
Based on 1 publication(s) in Google Scholar
Serotonin-d4 (5-Hydroxytryptamine-d4) hydrochloride is the deuterium labeled Serotonin (hydrochloride) (HY-B1473). Serotonin (5-Hydroxytryptamine) hydrochloride is a monoamine neurotransmitter in the CNS and an endogenous 5-HT receptor agonist. Serotonin hydrochloride is also a catechol O-methyltransferase (COMT) inhibitor with a Ki of 44 μM.
For research use only. We do not sell to patients.
- Purity: 99.22%
- CAS No.: 2469263-61-2
- Formula: C10H9D4ClN2O
- Molecular Weight:216.70
-
Storage:
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
-
Solvent & Solubility
- Purity & Documentation
- References
-
Help & FAQs
Publications Citing Use of MedChemExpress (MCE) Serotonin-d4 hydrochloride
MoreAll Endogenous Metabolite Isoforms
MoreAll 5-HT Receptor Isoforms
More
Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
-
CAS No. 2469263-61-2
-
Unlabeled Cas 153-98-0
-
Appearance Solid
-
Molecular Weight 216.70
-
Formula C10H9D4ClN2O
-
Color Off-white to gray
-
SMILES
OC1=CC2=C(NC=C2C([2H])([2H])C([2H])([2H])N)C=C1.Cl
-
Synonyms
5-Hydroxytryptamine-d4 hydrochloride; 5-HT-d4 hydrochloride
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Publications (1)
-
Journal Impact Factor
-
Most Recent
-
Cell Discov
TGM2-mediated serotonylation of GPX4 confers ferroptosis resistance to promote gastric tumorigenesis. [Abstract]2026 Apr 28;12(1):30. PMID: 42049702
Solvent & Solubility
H2O : 200 mg/mL (922.93 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
-
Data Sheet (271 KB)
-
SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
-
Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 4.6147 mL | 23.0734 mL | 46.1467 mL | 115.3669 mL |
| 5 mM | 0.9229 mL | 4.6147 mL | 9.2293 mL | 23.0734 mL | |
| 10 mM | 0.4615 mL | 2.3073 mL | 4.6147 mL | 11.5367 mL | |
| 15 mM | 0.3076 mL | 1.5382 mL | 3.0764 mL | 7.6911 mL | |
| 20 mM | 0.2307 mL | 1.1537 mL | 2.3073 mL | 5.7683 mL | |
| 25 mM | 0.1846 mL | 0.9229 mL | 1.8459 mL | 4.6147 mL | |
| 30 mM | 0.1538 mL | 0.7691 mL | 1.5382 mL | 3.8456 mL | |
| 40 mM | 0.1154 mL | 0.5768 mL | 1.1537 mL | 2.8842 mL | |
| 50 mM | 0.0923 mL | 0.4615 mL | 0.9229 mL | 2.3073 mL | |
| 60 mM | 0.0769 mL | 0.3846 mL | 0.7691 mL | 1.9228 mL | |
| 80 mM | 0.0577 mL | 0.2884 mL | 0.5768 mL | 1.4421 mL | |
| 100 mM | 0.0461 mL | 0.2307 mL | 0.4615 mL | 1.1537 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Serotonin-d4 hydrochloride Related Classifications
HY-B1473S Related Classifications
Powered by Bioz