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Cat. No.: HY-14794B

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Dextromilnacipran hydrochloride

(Synonyms: (1R,2S)-Milnacipran hydrochloride; F2696 hydrochloride)

Dextromilnacipran ((1R,2S)-Milnacipran; F2696) hydrochloride is an orally active Serotonin (HY-B1473A)/Noradrenaline (HY-13715) transporter inhibitor. Dextromilnacipran hydrochloride inhibits Serotonin and Noradrenaline reuptake. Dextromilnacipran hydrochloride can be used for the research of depression, fibromyalgia.

For research use only. We do not sell to patients.

CAS No.: 175131-61-0
Formula: C₁₅H₂₃ClN₂O
Molecular Weight:282.81

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Dextromilnacipran hydrochloride Chemical Structure

CAS No.: 175131-61-0

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Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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- Cellular Effect
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Biological Activity

Description

All Adrenergic Receptor Isoforms :

Cellular Effect

Cell Line	Type	Value	Description	References
HEK293	IC₅₀	0.05 μM Compound: Milnacipran	Inhibition of the Norepinephrine transporter (NET, SLC6A2) as assessed by GPCR-mediated changes in cell morphology using the impedance-based transporter activity through receptor activation (TRACT) assay in HEK-293 JumpIN-SLC6A2 cells (PubChem AID: 174586 Inhibition of the Norepinephrine transporter (NET, SLC6A2) as assessed by GPCR-mediated changes in cell morphology using the impedance-based transporter activity through receptor activation (TRACT) assay in HEK-293 JumpIN-SLC6A2 cells (PubChem AID: 174586	[PMID: 34112854]

Chemical Information

CAS No. 175131-61-0
Molecular Weight 282.81
Formula C₁₅H₂₃ClN₂O
SMILES

CCN(CC)C([C@@]1(C2=CC=CC=C2)[C@H](C1)CN)=O.Cl
Synonyms

(1R,2S)-Milnacipran hydrochloride; F2696 hydrochloride
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Mostafa IM, et al. Utility of the chromogenic and fluorogenic properties of benzofurazan for the assay of milnacipran in human urine and plasma. RSC Adv. 2018;8(39):22154-22160. Published 2018 Jun 15. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Biological Activity
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Dextromilnacipran hydrochloride

All Adrenergic Receptor Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

Dextromilnacipran hydrochloride Related Classifications

HY-14794B Related Classifications