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Results for "

Leukotriene+Receptor

" in MedChemExpress (MCE) Product Catalog:

By Targets:	G protein-coupled Bile Acid Receptor 1 (1) Isotope-Labeled Compounds (3) Leukotriene Receptor (25) Lipoxygenase (2) Reference Standards (3) TNF Receptor (1)
By Research Areas:	Cancer (6) Endocrinology (1) Inflammation/Immunology (25) Metabolic Disease (1)

Inhibitors & Agonists

Recombinant Proteins

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-13315

Montelukast sodium Maximum Cited Publications 14 Publications Verification MK0476	Leukotriene Receptor	Inflammation/Immunology Cancer
Montelukast sodium (MK0476) is a potent, selective and orally active antagonist of *cysteinyl leukotriene receptor* 1 (CysLT₁)**. Montelukast sodium can be used for the reseach of asthma and liver injury. Montelukast sodium also has an antioxidant effect in intestinal ischemia-reperfusion injury, and could reduce cardiac damage. Montelukast sodium decreases eosinophil infiltration into the asthmatic airways. Montelukast sodium can also be used for COVID-19 research .

HY-13315A

Montelukast Maximum Cited Publications 14 Publications Verification MK0476 free base	Leukotriene Receptor	Inflammation/Immunology Cancer
Montelukast (MK0476 free base) is a potent, selective and orally active antagonist of *cysteinyl leukotriene receptor* 1 (CysLT₁)**. Montelukast can be used for the reseach of asthma and liver injury. Montelukast also has an antioxidant effect in intestinal ischemia-reperfusion injury, and could reduce cardiac damage. Montelukast decreases eosinophil infiltration into the asthmatic airways. Montelukast can also be used for COVID-19 research .

HY-107609

BAY-u 9773	Leukotriene Receptor	Inflammation/Immunology Endocrinology
BAY-u 9773 is a selective cysteinyl-leukotriene receptor antagonist. BAY-u 9773 competitively antagonizes cysteinyl-leukotriene-induced contractions at typical and atypical cysteinyl-leukotriene receptors with comparable activity. BAY-u 9773 can be used for the research of trichomoniasis .

HY-76511

Verlukast MK-679; L 668019	Leukotriene Receptor	Inflammation/Immunology
Verlukast is a potent, selective, and orally active antagonist of *leukotriene receptor*. Verlukast has the potential for the research of asthma .

HY-14938

Tipelukast KCA 757; MN 001	Leukotriene Receptor	Inflammation/Immunology
Tipelukast (KCA 757) is a sulfidopeptide *leukotriene receptor* antagonist, an orally bioavailable anti-inflammatory agent and used for the treatment of asthma.

HY-107607

FPL-55712 free base	Leukotriene Receptor	Inflammation/Immunology
FPL-55712 free base is a *leukotriene receptor* antagonist. FPL-55712 free base is also an antagonist of slow reacting substance of anaphylaxis (*SRS-A). FPL-55712 free base inhibits leukotriene-induced bronchoconstriction .*

HY-112532

REV 5901	Leukotriene Receptor Lipoxygenase	Inflammation/Immunology Cancer
REV 5901 is a competitive and orally active antagonist of *leukotriene receptor, with a K_i* of 0.7 μM. REV 5901 is also a 5-lipoxygenase inhibitor. REV 5901 can be used for the research of asthma in which leukotriene release be involved. REV 5901 can be used for the study of colon carcinoma .

HY-13315B

Montelukast dicyclohexylamine MK0476 dicyclohexylamine	Leukotriene Receptor	Inflammation/Immunology Cancer
Montelukast (MK0476) dicyclohexylamine is a potent, selective and orally active antagonist of *cysteinyl leukotriene receptor* 1 (CysLT₁)**. Montelukast dicyclohexylamine can be used for the reseach of asthma and liver injury. Montelukast dicyclohexylamine also has an antioxidant effect in intestinal ischemia-reperfusion injury, and could reduce cardiac damage. Montelukast dicyclohexylamine decreases eosinophil infiltration into the asthmatic airways. Montelukast dicyclohexylamine can also be used for COVID-19 research .

HY-165155

*CysLT1 receptor* antagonist-1**	Leukotriene Receptor	Inflammation/Immunology
CysLT1 receptor antagonist-1 (Compound 4) is an antagonist for *cysteinyl leukotriene receptor* 1 (CysLT1R) with an IC₅₀** of 3.9 μM. CysLT1 receptor antagonist-1 exhibits weak agonist activity against *G-protein-coupled bile acid receptor* 1 (GPBAR1*) with an efficact of 23% at 10 μM. CysLT1 receptor* antagonist-1 can be used for asthma and allergic diseases researchs .

HY-176921

ONO-2570366	Leukotriene Receptor	Inflammation/Immunology
ONO-2570366 (Compound 11a) is an antagonist of the cysteinyl leukotriene receptors CysLT1R and CysLT2R (IC₅₀ = 14 nM). ONO-2570366 inhibits the binding of LTD₄receptor conformation, thereby preventing the Gq signaling pathway mediated by receptor activation. ONO-2570366 can be used for the researches of inflammation and immunology, such as asthma .

HY-13315AR

Montelukast (Standard) MK0476 free base (Standard)	Reference Standards Leukotriene Receptor	Inflammation/Immunology
Montelukast (Standard) is the analytical standard of Montelukast. This product is intended for research and analytical applications. Montelukast (MK0476 free base) is a potent, selective and orally active antagonist of *cysteinyl leukotriene receptor* 1 (CysLT₁)**. Montelukast can be used for the reseach of asthma and liver injury. Montelukast also has an antioxidant effect in intestinal ischemia-reperfusion injury, and could reduce cardiac damage. Montelukast decreases eosinophil infiltration into the asthmatic airways. Montelukast can also be used for COVID-19 research .

HY-147086

CAY10789	Leukotriene Receptor G protein-coupled Bile Acid Receptor 1 TNF Receptor	Metabolic Disease Inflammation/Immunology
CAY10789 is a potent CysLT1R (cysteinyl leukotriene receptor 1) antagonist (IC₅₀=2.80 μM) and GPBAR1 (G-protein-coupled bile acid receptor 1) agonist (EC₅₀=3 μM). CAY10789 significantly reduces the adhesion of U937 cells to HAEC, reduces the expression of TNF-α. CAY10789 shows very promising metabolic stability and excellent pharmacokinetics. CAY10789 can be used for the research of colitis, metabolic syndromes, and other GPBAR1/CysLT1R-related diseases .

HY-76511S

Verlukast-d6 MK-679-d₆; L 668019-d₆	Isotope-Labeled Compounds Leukotriene Receptor	Inflammation/Immunology
Verlukast-d₆ is a deuterium labeled Verlukast. Verlukast is a potent, selective, and orally active antagonist of leukotriene receptor. Verlukast has the potential for the research of asthma .

HY-13315S1

Montelukast-d6 sodium MK0476-d₆	Leukotriene Receptor	Inflammation/Immunology
Montelukast-d₆ (sodium) is the deuterium labeled Montelukast (sodium). Montelukast sodium is a potent, selective and orally active antagonist of cysteinyl leukotriene receptor 1 (Cysltr1). Montelukast sodium can be used for the reseach of asthma and liver injury. Montelukast sodium also has an antioxidant effect in intestinal ischemia-reperfusion injury, and could reduce cardiac damage .

HY-19395

MEN-91507	Leukotriene Receptor	Inflammation/Immunology
MEN-91507 is an orally activecysteinyl leukotriene receptor 1 (CysLTR1) receptor antagonist. MEN-91507 behaves as insurmountable antagonist of Leukotriene D4 (HY-113456)-induced calcium transients, with a pK_b of 10.25. MEN-91507 can inhibit Leukotriene D4-induced bronchoconstriction and microvascular leakage in guinea-pigs. MEN-91507 can be used for the researches of inflammation, immunology .

HY-120486

LY203647	Leukotriene Receptor	Inflammation/Immunology
LY203647 is an orally active antagonist for *leukotriene receptor* LTD4 and LTE4. LY203647 can be used in research about asthma and other inflammation diseases .

HY-106806

NZ-107	Leukotriene Receptor	Inflammation/Immunology
NZ-107 is an orally active *leukotriene receptor* antagonist. NZ-107 can inhibit anaphylaxis reaction. NZ-107 can be used for the researches of inflammation and immunology .

HY-118958

Ablukast Ro 23-3544	Leukotriene Receptor	Inflammation/Immunology
Ablukast (Ro 23-3544) is a specific and active *leukotriene receptor* antagonist. Ablukast effectively reduces LTC4- and antigen-induced bronchoconstriction . Ablukast is LTD4 receptor antagonist .

HY-W744275

Tipelukast-d6	Isotope-Labeled Compounds Leukotriene Receptor	Inflammation/Immunology
Tipelukast-d₆ is the deuterium labeled Tipelukast (HY-14938). Tipelukast (KCA 757) is a sulfidopeptide leukotriene receptor antagonist, an orally bioavailable anti-inflammatory agent and used for the treatment of asthma.

HY-112532A

REV 5901 hydrochloride	Leukotriene Receptor Lipoxygenase	Inflammation/Immunology Cancer
REV 5901 hydrochloride is a competitive and orally active antagonist of *leukotriene receptor, with a K_i* of 0.7 μM. REV 5901 hydrochloride is also a 5-lipoxygenase inhibitor. REV 5901 hydrochloride can be used for the research of asthma in which leukotriene release be involved. REV 5901 hydrochloride can be used for the study of colon carcinoma .

HY-13315S

Montelukast-d6 MK0476-d6 free acid	Isotope-Labeled Compounds Leukotriene Receptor	Inflammation/Immunology
Montelukast-d₆ is the deuterium labeled Montelukast (sodium). Montelukast sodium is a potent, selective and orally active antagonist of cysteinyl leukotriene receptor 1 (Cysltr1). Montelukast sodium can be used for the reseach of asthma and liver injury. Montelukast sodium also has an antioxidant effect in intestinal ischemia-reperfusion injury, and could reduce cardiac damage .

HY-130138A

(5S,6R)-DiHETE	Leukotriene Receptor	Inflammation/Immunology
(5S,6R)-DiHETE is an enantiomer of (5,6)-DiHETEs. (5S,6R)-DiHETE can be recognized by leukotriene receptors (LTD4 receptors). (5S,6R)-DiHETE can induce guinea pig isolated ileum contraction with an EC₅₀ of 1.3 μM, and this effect can be inhibited by LTD4 receptor antagonists .

HY-13315R

Montelukast sodium (Standard) MK0476 (Standard)	Reference Standards Leukotriene Receptor	Inflammation/Immunology
Montelukast (sodium) (Standard) is the analytical standard of Montelukast (sodium). This product is intended for research and analytical applications. Montelukast sodium (MK0476) is a potent, selective and orally active antagonist of *cysteinyl leukotriene receptor* 1 (CysLT₁)**. Montelukast sodium can be used for the reseach of asthma and liver injury. Montelukast sodium also has an antioxidant effect in intestinal ischemia-reperfusion injury, and could reduce cardiac damage. Montelukast sodium decreases eosinophil infiltration into the asthmatic airways. Montelukast sodium can also be used for COVID-19 research .

HY-130138B

(5S,6R)-DiHETEs (5S,6R)-(11E)-DiHETE	Leukotriene Receptor	Inflammation/Immunology
(5S,6R)-DiHETEs is the isomer of (5S,6R)-DiHETE (HY-130138A). (5S,6R)-DiHETE can be recognized by leukotriene receptors (LTD4 receptors). (5S,6R)-DiHETE can induce guinea pig isolated ileum contraction with an EC₅₀ of 1.3 μM, and this effect can be inhibited by LTD4 receptor antagonists .

HY-13315BR

Montelukast dicyclohexylamine (Standard) MK0476 dicyclohexylamine (Standard)	Reference Standards Leukotriene Receptor	Inflammation/Immunology Cancer
Montelukast (dicyclohexylamine) (Standard) is the analytical standard of Montelukast (dicyclohexylamine). This product is intended for research and analytical applications. Montelukast (MK0476) dicyclohexylamine is a potent, selective and orally active antagonist of cysteinyl leukotriene receptor 1 (CysLT1). Montelukast dicyclohexylamine can be used for the reseach of asthma and liver injury. Montelukast dicyclohexylamine also has an antioxidant effect in intestinal ischemia-reperfusion injury, and could reduce cardiac damage. Montelukast dicyclohexylamine decreases eosinophil infiltration into the asthmatic airways. Montelukast dicyclohexylamine can also be used for COVID-19 research .

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P705954

	GPR17 Protein, Human (Cell-Free, His) GPR17; Uracil nucleotide/cysteinyl leukotriene receptor; UDP/CysLT receptor; G-protein coupled receptor 17; P2Y-like receptor; R12	Human	E. coli Cell-free

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Cat. No.	Product Name	Chemical Structure

HY-76511S

Verlukast-d6
Verlukast-d₆ is a deuterium labeled Verlukast. Verlukast is a potent, selective, and orally active antagonist of leukotriene receptor. Verlukast has the potential for the research of asthma .

HY-13315S1

Montelukast-d6 sodium
Montelukast-d₆ (sodium) is the deuterium labeled Montelukast (sodium). Montelukast sodium is a potent, selective and orally active antagonist of cysteinyl leukotriene receptor 1 (Cysltr1). Montelukast sodium can be used for the reseach of asthma and liver injury. Montelukast sodium also has an antioxidant effect in intestinal ischemia-reperfusion injury, and could reduce cardiac damage .

HY-W744275

Tipelukast-d6
Tipelukast-d₆ is the deuterium labeled Tipelukast (HY-14938). Tipelukast (KCA 757) is a sulfidopeptide leukotriene receptor antagonist, an orally bioavailable anti-inflammatory agent and used for the treatment of asthma.

HY-13315S

Montelukast-d6
Montelukast-d₆ is the deuterium labeled Montelukast (sodium). Montelukast sodium is a potent, selective and orally active antagonist of cysteinyl leukotriene receptor 1 (Cysltr1). Montelukast sodium can be used for the reseach of asthma and liver injury. Montelukast sodium also has an antioxidant effect in intestinal ischemia-reperfusion injury, and could reduce cardiac damage .

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