FPL-55712 free base
Based on 1 Customer Validation
FPL-55712 free base is a leukotriene receptor antagonist. FPL-55712 free base is also an antagonist of slow reacting substance of anaphylaxis (SRS-A). FPL-55712 free base inhibits leukotriene-induced bronchoconstriction.
For research use only. We do not sell to patients.
- Purity: 98.0%
- CAS No.: 40785-97-5
- Formula: C27H30O9
- Molecular Weight:498.52
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
All Leukotriene Receptor Isoforms
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Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| RBL-1 | IC50 |
21 μM
Compound: FPL-55712
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The compound was tested for inhibitory activity against 5-lipoxygenase in rat RBL-1 cells
The compound was tested for inhibitory activity against 5-lipoxygenase in rat RBL-1 cells
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[PMID: 1635053] |
Chemical Information
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CAS No. 40785-97-5
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Appearance Solid
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Molecular Weight 498.52
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Formula C27H30O9
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Color White to off-white
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SMILES
O=C(C(OC1=C(CCC)C(OCC(COC2=CC=C(C(O)=C2CCC)C(C)=O)O)=CC=C13)=CC3=O)O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Purity & Documentation
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Data Sheet (266 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
[1]. O'Donnell M, et al. Pharmacologic properties of FPL 55712 administered by aerosol. Agents Actions. 1984 Jan;14(1):43-8. [Content Brief]
[2]. Folkerts G, Vet al. Leukotrienes mediate tracheal hyperresponsiveness after nitric oxide synthesis inhibition. Eur J Pharmacol. 1995 Oct 16;285(2):R1-2. [Content Brief]
[3]. Chand N. FPL 55712 -- an antagonist of slow reacting substance of anaphylaxis (SRS-A): a review. Agents Actions. 1979 Jun;9(2):133-40. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
FPL-55712 free base Related Classifications
HY-107607 Related Classifications
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