40785-97-5
Chemical Structure
FPL-55712 free base
- CAS No.: 40785-97-5
- Formula:C27H30O9
- Molecular Weight:498.52
IUPAC Name: 7-(3-(4-acetyl-3-hydroxy-2-propylphenoxy)-2-hydroxypropoxy)-4-oxo-8-propyl-4H-chromene-2-carboxylic acid
InChIKey: LMQBMWHHGVZWMR-UHFFFAOYSA-N
SMILES: O=C(C(OC1=C(CCC)C(OCC(COC2=CC=C(C(O)=C2CCC)C(C)=O)O)=CC=C13)=CC3=O)O
Biological Activity: FPL-55712 free base is a leukotriene receptor antagonist. FPL-55712 free base is also an antagonist of slow reacting substance of anaphylaxis (SRS-A). FPL-55712 free base inhibits leukotriene-induced bronchoconstriction[1][2][3].
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FPL-55712 free base | 98.0% | FPL-55712 free base is a leukotriene receptor antagonist. FPL-55712 free base is also an antagonist of slow reacting substance of anaphylaxis (SRS-A). FPL-55712 free base inhibits leukotriene-induced bronchoconstriction. | ||||||||||||||||||||
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- [1]. O'Donnell M, et al. Pharmacologic properties of FPL 55712 administered by aerosol. Agents Actions. 1984 Jan;14(1):43-8. [Content Brief]
- [2]. Folkerts G, Vet al. Leukotrienes mediate tracheal hyperresponsiveness after nitric oxide synthesis inhibition. Eur J Pharmacol. 1995 Oct 16;285(2):R1-2. [Content Brief]
- [3]. Chand N. FPL 55712 -- an antagonist of slow reacting substance of anaphylaxis (SRS-A): a review. Agents Actions. 1979 Jun;9(2):133-40. [Content Brief]
Keywords