1. GPCR/G Protein
  2. Leukotriene Receptor
  3. Montelukast-d6

Montelukast-d6 (Synonyms: MK0476-d6 free acid)

Cat. No.: HY-13315S
Handling Instructions

Montelukast-d6 (MK0476-d6 free acid) is the deuterium labeled Montelukast (sodium). Montelukast sodium is a potent, selective and orally active antagonist of cysteinyl leukotriene receptor 1 (Cysltr1). Montelukast sodium can be used for the reseach of asthma and liver injury. Montelukast sodium also has an antioxidant effect in intestinal ischemia-reperfusion injury, and could reduce cardiac damage.

For research use only. We do not sell to patients.

Montelukast-d6 Chemical Structure

Montelukast-d6 Chemical Structure

CAS No. : 1093746-29-2

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Description

Montelukast-d6 (MK0476-d6 free acid) is the deuterium labeled Montelukast (sodium). Montelukast sodium is a potent, selective and orally active antagonist of cysteinyl leukotriene receptor 1 (Cysltr1). Montelukast sodium can be used for the reseach of asthma and liver injury. Montelukast sodium also has an antioxidant effect in intestinal ischemia-reperfusion injury, and could reduce cardiac damage[1].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

592.22

Formula

C35H30D6ClNO3S

CAS No.
SMILES

O=C(O)CC1(CS[[email protected]@H](C2=CC=CC(/C=C/C3=NC4=CC(Cl)=CC=C4C=C3)=C2)CCC5=CC=CC=C5C(C([2H])([2H])[2H])(O)C([2H])([2H])[2H])CC1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Montelukast-d6
Cat. No.:
HY-13315S
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