Montelukast-d6 sodium
Based on 1 publication(s) in Google Scholar
Montelukast-d6 (sodium) is the deuterium labeled Montelukast (sodium). Montelukast sodium is a potent, selective and orally active antagonist of cysteinyl leukotriene receptor 1 (Cysltr1). Montelukast sodium can be used for the reseach of asthma and liver injury. Montelukast sodium also has an antioxidant effect in intestinal ischemia-reperfusion injury, and could reduce cardiac damage.
For research use only. We do not sell to patients.
- CAS No.: 2673270-26-1
- Formula: C35H29D6ClNNaO3S
- Molecular Weight:614.20
-
Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
-
HY-101988S
Prostaglandin D2-d4
-
HY-B1452
Licofelone
-
HY-B0150S
Nicotinamide-d4
-
HY-B0625S
Ciclesonide-d7
-
HY-108396
γ-Linolenic acid ethyl ester
-
HY-B0674S
Ebastine-d5
-
HY-B0157S
Ketotifen-13C,d3
-
HY-17043S2
Loratadine-d4-1
-
HY-B1452R
Licofelone (Standard)
-
HY-100573S
Necrosulfonamide-d4
-
HY-23188
Loratadine-d5-1
-
HY-120255AS
17(S)-HDHA-d5
Publications Citing Use of MedChemExpress (MCE) Montelukast-d6 sodium
MoreAll Leukotriene Receptor Isoforms
More
Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
-
CAS No. 2673270-26-1
-
Unlabeled Cas 151767-02-1
-
Appearance Solid
-
Molecular Weight 614.20
-
Formula C35H29D6ClNNaO3S
-
Color White to off-white
-
SMILES
[2H]C([2H])([2H])C(C([2H])([2H])[2H])(O)C(C=CC=C1)=C1CC[C@H](C2=CC(/C=C/C3=NC4=C(C=CC(Cl)=C4)C=C3)=CC=C2)SCC5(CC5)CC(O[Na])=O
-
Synonyms
MK0476-d6
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Publications (1)
-
Journal Impact Factor
-
Most Recent
-
Neurotherapeutics
Montelukast alleviates neuroinflammation and improves motor functions in the line 61 model of Parkinson's disease: An exploratory study. [Abstract]2025 Jul 31:e00690. PMID: 40750523
Purity & Documentation
-
Data Sheet (271 KB)
-
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
-
Handling Instructions (2659 KB)
References
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
[2]. Pu S, et, al. Montelukast Prevents Mice Against Acetaminophen-Induced Liver Injury. Front Pharmacol. 2019 Sep 18; 10:1070.;William RHJ, et, al. A role for cysteinyl leukotrienes in airway remodeling in a mouse asthma model. Am J Respir Crit Care Med. 2002 Jan 1; 165(1): 108-16. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Montelukast-d6 sodium Related Classifications
HY-13315S1 Related Classifications
Powered by Bioz