Montelukast (Standard)
Based on 1 Customer Validation
Montelukast (Standard) is the analytical standard of Montelukast. This product is intended for research and analytical applications. Montelukast (MK0476 free base) is a potent, selective and orally active antagonist of cysteinyl leukotriene receptor 1 (CysLT1). Montelukast can be used for the reseach of asthma and liver injury. Montelukast also has an antioxidant effect in intestinal ischemia-reperfusion injury, and could reduce cardiac damage. Montelukast decreases eosinophil infiltration into the asthmatic airways. Montelukast can also be used for COVID-19 research.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Reinheit : 98.89%
- CAS. Nr.: 158966-92-8
- Formel: C35H36ClNO3S
- Molecular Weight:586.18
-
Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Product Information
-
Chemical Information
- Reinheit & Dokumentation
-
Help & FAQs
-
HY-13315A
MontelukastCysLT1 Antagonist -
HY-17492
ZafirlukastLeukotriene Receptor Antagonist -
HY-13315
Montelukast sodiumCysltr1 Antagonist -
HY-19989A
MK-571 sodiumABCC1/MRP4 Inhibitor -
HY-B0290
PranlukastEndogenous Metabolite -
HY-13628
EtalocibLTB4 Receptor Antagonist -
HY-19989
MK-571ABCC1/MRP4 Inhibitor -
HY-17492R
Zafirlukast (Standard)Leukotriene Receptor Antagonist -
HY-15744
LY255283LTB4 Receptor Antagonist -
HY-B0290R
Pranlukast (Standard)Endogenous Metabolite -
HY-11063
FingolimodS1P Antagonist -
HY-76511
VerlukastLeukotriene Receptor Antagonist
Product Information
Information
Anwendung
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
-
CAS. Nr. 158966-92-8
-
Appearance Solid
-
Molecular Weight 586.18
-
Formel C35H36ClNO3S
-
Color Off-white to light yellow
-
SMILES
O=C(O)CC1(CS[C@@H](C2=CC=CC(/C=C/C3=NC4=CC(Cl)=CC=C4C=C3)=C2)CCC5=CC=CC=C5C(C)(O)C)CC1
-
Synonyms
MK0476 free base (Standard)
-
Versand
Room temperature in continental US; may vary elsewhere.
-
Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
-
SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
-
Handling Instructions (2659 KB)
Verweise
[1]. Pu S, et, al. Montelukast Prevents Mice Against Acetaminophen-Induced Liver Injury. Front Pharmacol. 2019 Sep 18; 10:1070. [Content Brief]
[2]. William RHJ, et, al. A role for cysteinyl leukotrienes in airway remodeling in a mouse asthma model. Am J Respir Crit Care Med. 2002 Jan 1; 165(1): 108-16. [Content Brief]
[3]. Langlois A, et al. Montelukast regulates eosinophil protease activity through a leukotriene-independent mechanism. J Allergy Clin Immunol. 2006;118(1):113-119. [Content Brief]
[4]. Khan AR, et al. Montelukast in hospitalized patients diagnosed with COVID-19. J Asthma. 2022 Apr;59(4):780-786. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Montelukast (Standard) Related Classifications
HY-13315AR Related Classifications
Powered by Bioz