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Results for "

Phosphatidylinositol 4,5-bisphosphate

" in MedChemExpress (MCE) Product Catalog:

11

Inhibitors & Agonists

1

Fluorescent Dyes

1

Biochemical Assay Reagents

5

Peptides

1

Natural
Products

6

Recombinant Proteins

1

Isotope-Labeled Compounds

10

Antibodies

Targets Recommended:
Cat. No. 상품명 Target 연구분야 Chemical Structure
  • HY-114457

    L-alpha-Phosphatidylinositol-4,5-bisphosphate; (PtdIns)-(4,5)-P2

    Phospholipase Inflammation/Immunology
    Phosphatidylinositol 4,5-bisphosphate (L-alpha-Phosphatidylinositol-4,5-bisphosphate) is a plasma membrane lipid that is enriched in the cytoplasmic leaflet of the plasma membrane. Phosphatidylinositol 4,5-bisphosphate serves as a substrate for phospholipase C and class I PI3K, generating diacylglycerol, inositol (1,4,5)-trisphosphate, and phosphatidylinositol (3,4,5)-trisphosphate. Phosphatidylinositol 4,5-bisphosphate contributes to lamellipodial protrusion, directional cell migration, focal adhesion lipid generation, and trafficking of the GABAA receptor. Phosphatidylinositol 4,5-bisphosphate can be used in research related to acute lung injury and pulmonary edema .
    Phosphatidylinositol 4,5-bisphosphate
  • HY-P1116
    PBP10
    1 Publications Verification

    Bacterial Reactive Oxygen Species (ROS) Interleukin Related Infection Inflammation/Immunology
    PBP10 is a decapeptide. PBP10 selectively binds to lipoteichoic acid (LTA), lipopolysaccharide (LPS) and phosphatidylinositol-4,5-bisphosphate (PIP2). PBP10 penetrates cell membranes and possesses bactericidal, anti-inflammatory, cell motility-inhibiting and actin assembly-regulating activities. PBP10 is applicable to relevant research on bacterial infections, microbe-induced inflammation, skin and soft tissue infections, as well as sepsis .
    PBP10
  • HY-167548

    PKC Potassium Channel Others
    L-α-Phosphatidylinositol-4,5-bisphosphate ammonium is a key signaling lipid. L-α-Phosphatidylinositol-4,5-bisphosphate ammonium is an activator of PKC in the presence of calcium ions and phospholipid serine. L-α-Phosphatidylinositol-4,5-bisphosphate ammonium is also an antagonist of the KIR3.4 (ATP-sensitive potassium, KATP) channel. L-α-Phosphatidylinositol-4,5-bisphosphate ammonium can be used in research related to signal transduction, ion channel regulation, and membrane transport.
    L-α-Phosphatidylinositol-4,5-bisphosphate ammonium
  • HY-P1116A
    PBP10 TFA
    1 Publications Verification

    Bacterial Infection Inflammation/Immunology
    PBP10 TFA is a decapeptide. PBP10 TFA selectively binds to lipoteichoic acid (LTA), lipopolysaccharide (LPS) and phosphatidylinositol-4,5-bisphosphate (PIP2). PBP10 TFA penetrates cell membranes and possesses bactericidal, anti-inflammatory, cell motility-inhibiting and actin assembly-regulating activities. PBP10 TFA is applicable to relevant research on bacterial infections, microbe-induced inflammation, skin and soft tissue infections, as well as sepsis .
    PBP10 TFA
  • HY-146948S

    Isotope-Labeled Compounds Others
    D-Myo-phosphatidylinositol 4,5-bisphosphate diC16-d5 is deuterium labeled D-Myo-phosphatidylinositol 4,5-bisphosphate diC16.
    D-Myo-phosphatidylinositol 4,5-bisphosphate diC16-d5
  • HY-P1045
    187-1, N-WASP inhibitor
    1 Publications Verification

    Arp2/3 Complex Others
    187-1, N-WASP inhibitor, a 14-aa cyclic peptide, is an allosteric neural Wiskott-Aldrich syndrome protein (N-WASP) inhibitor. 187-1, N-WASP inhibitor potently inhibits actin assembly induced by phosphatidylinositol 4,5-bisphosphate (PIP2) with an IC50 of 2 μM. 187-1, N-WASP inhibitor prevents the activation of Arp2/3 complex by N-WASP by stabilizing the autoinhibited state of the protein .
    187-1, N-WASP inhibitor
  • HY-150135B

    Inositol 1,4,5-trisphosphate tripotassium; Ins(1,4,5)-P3 tripotassium

    Calcium Channel Neurological Disease
    D-myo-Inositol 1,4,5-trisphosphate tripotassium, a second messenger, elicits Ca 2+ mobilization. D-myo-Inositol 1,4,5-trisphosphate tripotassium inhibits the binding of phosphoinositide-specific phospholipase C-delta 1 (PLC-delta 1) to bilayer membranes composed of phosphatidylcholine (PC) and phosphatidylinositol 4,5-bisphosphate (PIP2) .
    D-myo-Inositol 1,4,5-trisphosphate tripotassium
  • HY-P1045A

    Arp2/3 Complex Others
    187-1, N-WASP inhibitor TFA, a 14-aa cyclic peptide, is an allosteric neural Wiskott-Aldrich syndrome protein (N-WASP) inhibitor. 187-1, N-WASP inhibitor TFA potently inhibits actin assembly induced by phosphatidylinositol 4,5-bisphosphate (PIP2) with an IC50 of 2 μM. 187-1, N-WASP inhibitor TFA prevents the activation of Arp2/3 complex by N-WASP by stabilizing the autoinhibited state of the protein .
    187-1, N-WASP inhibitor TFA
  • HY-W403046A

    Drug Metabolite Calcium Channel Neurological Disease
    D-myo-Inositol-4-phosphate monoammonium is a metabolite of D-myo-Inositol 1,4,5-trisphosphate. D-myo-Inositol 1,4,5-trisphosphate, a second messenger, elicits Ca 2+ mobilization. D-myo-Inositol 1,4,5-trisphosphate inhibits the binding of phosphoinositide-specific phospholipase C-delta 1 (PLC-delta 1) to bilayer membranes composed of phosphatidylcholine (PC) and phosphatidylinositol 4,5-bisphosphate (PIP2) .
    D-myo-Inositol-4-phosphate monoammonium
  • HY-D3302

    DOPI-4,5-P2-biotin sodium; Phosphatidylinositol-4,5-diphosphate C-8-biotin sodium; PI(4,5)P2-biotin sodium

    Biochemical Assay Reagents Others
    PtdIns-(4,5)-P2-biotin (DOPI-4,5-P2-biotin) sodium is a biotin-labeled phosphatidylinositol 4,5-bisphosphate (PIP2) derivative. PtdIns-(4,5)-P2-biotin sodium uses a biotin tag to capture and purify natural PIP2 molecules and their interacting proteins.
    PtdIns-(4,5)-P2-biotin sodium
  • HY-179554

    PI(4,5)P2-fluorescein triethylammonium

    Fluorescent Dye Others
    PtdIns-(4,5)-P2-fluorescein (PI(4,5)P2-fluorescein) triethylammonium is a fluorescently labeled phosphatidylinositol-4,5-bisphosphate, which is a marked form of an important phospholipid signaling molecule (PIP2) on the cell membrane. PtdIns-(4,5)-P2-fluorescein triethylammonium can be used to detect proteins that interact with phosphatidylinositol-4,5-bisphosphate, such as PI3K, PTEN, and PH domain proteins, etc .
    PtdIns-(4,5)-P2-fluorescein triethylammonium

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