PtdIns-(4,5)-P2-biotin sodium  (Synonyms: DOPI-4,5-P2-biotin sodium; Phosphatidylinositol-4,5-diphosphate C-8-biotin sodium; PI(4,5)P2-biotin sodium)

PtdIns-(4,5)-P2-biotin (DOPI-4,5-P2-biotin) sodium is a biotin-labeled phosphatidylinositol 4,5-bisphosphate (PIP2) derivative. PtdIns-(4,5)-P2-biotin sodium uses a biotin tag to capture and purify natural PIP2 molecules and their interacting proteins.

The structure of PtdIns-(4,5)-P2-biotin sodium contains two key parts that work synergistically:
Biotin: Provides extremely strong specific binding affinity to streptavidin and avidin.
PtdIns-(4,5)-P2: Responsible for specific binding to target proteins within the cell (such as kinase PI3Kγ, phosphatase PTEN, or proteins containing a PH domain).

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

1053.82

C₃₅H₆₁N₃Na₃O₂₁P₃S

O[C@H]1[C@@H]([C@H]([C@@H]([C@@H]([C@@H]1OP(OC[C@@H](OC(CCCCCCC)=O)COC(CCCCCCCNC(CCCC[C@H]2SC[C@@]([H])([C@@]2(N(C3=O)[H])[H])N3[H])=O)=O)(O[Na])=O)O)O)OP(O)(O[Na])=O)OP(O)(O[Na])=O

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.