D-myo-Inositol 1,4,5-trisphosphate tripotassium
Based on 1 publication(s) in Google Scholar
D-myo-Inositol 1,4,5-trisphosphate tripotassium, a second messenger, elicits Ca2+ mobilization. D-myo-Inositol 1,4,5-trisphosphate tripotassium inhibits the binding of phosphoinositide-specific phospholipase C-delta 1 (PLC-delta 1) to bilayer membranes composed of phosphatidylcholine (PC) and phosphatidylinositol 4,5-bisphosphate (PIP2).
For research use only. We do not sell to patients.
- Purity : 98.00%
- CAS No.: 141611-11-2
- Formula: C6H12K3O15P3
- Molecular Weight:534.37
-
Storage:
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
-
Solvent & Solubility
- Purity & Documentation
- References
-
Help & FAQs
Publications Citing Use of MedChemExpress (MCE) D-myo-Inositol 1,4,5-trisphosphate tripotassium
MoreAll Calcium Channel Isoforms
More
Biological Activity
Description
Chemical Information
-
CAS No. 141611-11-2
-
Appearance Solid
-
Molecular Weight 534.37
-
Formula C6H12K3O15P3
-
Color White to off-white
-
SMILES
O[C@H]1[C@H]([C@@H]([C@H]([C@@H]([C@H]1O)OP(O)(O[K])=O)OP(O)(O[K])=O)O)OP(O)(O[K])=O
-
Synonyms
Inositol 1,4,5-trisphosphate tripotassium; Ins(1,4,5)-P3 tripotassium
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Publications (1)
-
Journal Impact Factor
-
Most Recent
-
Asian J Androl
Participation of the inositol 1,4,5-trisphosphate-gated calcium channel in the zona pellucida- and progesterone-induced acrosome reaction and calcium influx in human spermatozoa. [Abstract]2020 Mar-Apr;22(2):192-199. PMID: 31169139
Solvent & Solubility
In Vitro:
H2O : 50 mg/mL (93.57 mM; Need ultrasonic and warming)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
-
Data Sheet (279 KB)
-
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
-
Handling Instructions (2659 KB)
References
[1]. D M Gou, et al. D-myo-inositol 1,4,5-trisphosphate analogues as useful tools in biochemical studies of intracellular calcium mobilization. Bioorg Med Chem. 1994 Jan;2(1):7-13. [Content Brief]
[2]. M E Cifuentes, et al. D-myo-inositol 1,4,5-trisphosphate inhibits binding of phospholipase C-delta 1 to bilayer membranes. J Biol Chem. 1994 Jan 21;269(3):1945-8. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 1.8714 mL | 9.3568 mL | 18.7136 mL | 46.7841 mL |
| 5 mM | 0.3743 mL | 1.8714 mL | 3.7427 mL | 9.3568 mL | |
| 10 mM | 0.1871 mL | 0.9357 mL | 1.8714 mL | 4.6784 mL | |
| 15 mM | 0.1248 mL | 0.6238 mL | 1.2476 mL | 3.1189 mL | |
| 20 mM | 0.0936 mL | 0.4678 mL | 0.9357 mL | 2.3392 mL | |
| 25 mM | 0.0749 mL | 0.3743 mL | 0.7485 mL | 1.8714 mL | |
| 30 mM | 0.0624 mL | 0.3119 mL | 0.6238 mL | 1.5595 mL | |
| 40 mM | 0.0468 mL | 0.2339 mL | 0.4678 mL | 1.1696 mL | |
| 50 mM | 0.0374 mL | 0.1871 mL | 0.3743 mL | 0.9357 mL | |
| 60 mM | 0.0312 mL | 0.1559 mL | 0.3119 mL | 0.7797 mL | |
| 80 mM | 0.0234 mL | 0.1170 mL | 0.2339 mL | 0.5848 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
D-myo-Inositol 1,4,5-trisphosphate tripotassium Related Classifications
HY-150135B Related Classifications
Powered by Bioz