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Cat. No.: HY-103642

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D-myo-Inositol 1,4,5-trisphosphate hexapotassium salt

Name: D-myo-Inositol 1,4,5-trisphosphate hexapotassium salt
Brand: MedChemExpress
SKU: HY-103642
Price: 300.00 USD
Availability: PreOrder

(Synonyms: Inositol 1,4,5-trisphosphate hexapotassium salt; Ins(1,4,5)-P3 hexapotassium salt)

1 Cited Publications

Customer Review

Based on 1 publication(s) in Google Scholar

D-myo-Inositol 1,4,5-trisphosphate hexapotassium salt is the hexapotassium salt of D-myo-Inositol 1,4,5-trisphosphate (1,4,5-IP3), which is a second messenger that stimulates the discharge of calcium from the endoplasmic reticulum.

For research use only. We do not sell to patients.

CAS No.: 103476-24-0
Formula: C₆H₉K₆O₁₅P₃
Molecular Weight:648.64

Storage:

-20°C, sealed storage, away from moisture

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

D-myo-Inositol 1,4,5-trisphosphate hexapotassium salt Chemical Structure

CAS No.: 103476-24-0

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

HY-W794363
D-myo-Inositol-1,4,5,6-tetraphosphate sodium

Biological Activity
- Description
- In Vitro
Chemical Information
Publications (1)
Purity & Documentation
References
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Biological Activity

Description

All Calcium Channel Isoforms :

In Vitro

Second messenger D-myo-Inositol 1,4,5-trisphosphate (1,4,5-IP3) is served as an inositol phosphate derivative. The dissociation constant (K_D) for Pr55^Gag complexed with D-myo-Inositol 1,4,5-trisphosphate (an inositol with divalent phosphate groups and devoid of lipid groups) is 2170 μM. The binding affinities of D-myo-Inositol 1,4,5-trisphosphate (K_D=568 μM) and 1,3,4,5-IP4 (K_D=526 μM) for matrix (MA) are almost identical^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 103476-24-0
Appearance Solid
Molecular Weight 648.64
Formula C₆H₉K₆O₁₅P₃
Color White to off-white
SMILES

O[C@H]1[C@@H](OP(O[K])(O[K])=O)[C@H](O)[C@@H](OP(O[K])(O[K])=O)[C@H](OP(O[K])(O[K])=O)[C@H]1O
Synonyms

Inositol 1,4,5-trisphosphate hexapotassium salt; Ins(1,4,5)-P3 hexapotassium salt
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, sealed storage, away from moisture

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Publications (1)

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Asian J Androl

Participation of the inositol 1,4,5-trisphosphate-gated calcium channel in the zona pellucida- and progesterone-induced acrosome reaction and calcium influx in human spermatozoa. [Abstract]

2020 Mar-Apr;22(2):192-199. PMID: 31169139

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (281 KB)
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Anraku K, et al. Highly sensitive analysis of the interaction between HIV-1 Gag and phosphoinositide derivatives based on surface plasmon resonance. Biochemistry. 2010 Jun 29;49(25):5109-16. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Keywords

D-myo-Inositol 1,4,5-trisphosphate hexapotassium salt

1 Cited Publications

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Biological Activity
- Description
- In Vitro
Chemical Information
Publications (1)
Purity & Documentation
References

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D-myo-Inositol 1,4,5-trisphosphate hexapotassium salt

Publications Citing Use of MedChemExpress (MCE) D-myo-Inositol 1,4,5-trisphosphate hexapotassium salt

All Calcium Channel Isoforms