D-myo-Inositol-1,4,5-triphosphate trisodium
Based on 1 publication(s) in Google Scholar
D-myo-Inositol-1,4,5-triphosphate sodium salt is the trisodium salt of D-myo-Inositol 1,4,5-trisphosphate (1,4,5-IP3), which is a second messenger that stimulates the discharge of calcium from the endoplasmic reticulum.
For research use only. We do not sell to patients.
- Purity : 99.8%
- CAS No.: 141611-10-1
- Formula: C6H12Na3O15P3
- Molecular Weight:486.04
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Storage:
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Publications Citing Use of MedChemExpress (MCE) D-myo-Inositol-1,4,5-triphosphate trisodium
MoreAll Calcium Channel Isoforms
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Biological Activity
Description
In Vitro
Second messenger D-myo-Inositol 1,4,5-trisphosphate (1,4,5-IP3) is served as an inositol phosphate derivative. The dissociation constant (KD) for Pr55Gag complexed with D-myo-Inositol 1,4,5-trisphosphate (an inositol with divalent phosphate groups and devoid of lipid groups) is 2170 μM. The binding affinities of D-myo-Inositol 1,4,5-trisphosphate (KD=568 μM) and 1,3,4,5-IP4 (KD=526 μM) for matrix (MA) are almost identical[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 141611-10-1
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Appearance Solid
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Molecular Weight 486.04
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Formula C6H12Na3O15P3
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Color White to off-white
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SMILES
O=P(O)(O[Na])O[C@H]1[C@@H]([C@H]([C@H]([C@H]([C@@H]1O)OP(O)(O[Na])=O)O)O)OP(O)(O[Na])=O
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Synonyms
Inositol 1,4,5-trisphosphate trisodium; Ins(1,4,5)-P3 trisodium
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Publications (1)
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Journal Impact Factor
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Most Recent
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Asian J Androl
Participation of the inositol 1,4,5-trisphosphate-gated calcium channel in the zona pellucida- and progesterone-induced acrosome reaction and calcium influx in human spermatozoa. [Abstract]2020 Mar-Apr;22(2):192-199. PMID: 31169139
Solvent & Solubility
In Vitro:
DMSO : 10 mg/mL (20.57 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
H2O : 1.5 mg/mL (3.09 mM; Need ultrasonic and warming)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (278 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O / DMSO | 1 mM | 2.0574 mL | 10.2872 mL | 20.5744 mL | 51.4361 mL |
| DMSO | 5 mM | 0.4115 mL | 2.0574 mL | 4.1149 mL | 10.2872 mL |
| 10 mM | 0.2057 mL | 1.0287 mL | 2.0574 mL | 5.1436 mL | |
| 15 mM | 0.1372 mL | 0.6858 mL | 1.3716 mL | 3.4291 mL | |
| 20 mM | 0.1029 mL | 0.5144 mL | 1.0287 mL | 2.5718 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
D-myo-Inositol-1,4,5-triphosphate trisodium Related Classifications
HY-103642A Related Classifications
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