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RSV F

" in MedChemExpress (MCE) Product Catalog:

By Targets:	RSV (19) IGF-1R (1)
By Research Areas:	Cancer (1) Infection (19) Inflammation/Immunology (2)

Inhibitors & Agonists

Inhibitory Antibodies

Natural
Products

Recombinant Proteins

Targets Recommended: RSV

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-P9944

Palivizumab 3 Publications Verification MEDI 493	RSV	Infection Inflammation/Immunology Cancer
Palivizumab (MEDI 493) is a humanized monoclonal antibody against respiratory syncytial virus (RSV). Palivizumab can bind to RSV F protein with a K_d value of 1.4 nM. Palivizumab can prevent respiratory syncytial virus infection in cotton mice .

HY-109142

Ziresovir 5 Publications Verification AK0529; RO-0529	RSV	Infection
Ziresovir (AK0529;RO-0529) is a potent, selective, and orally bioavailable respiratory syncytial virus (RSV) fusion (F) protein (RSV F) protein inhibitor. Ziresovir shows anti-RSV activity (EC₅₀=3 nM) and highlights pharmacokinetics in animal species .

HY-P99647

Gontivimab ALX-0171; VR-465	RSV	Infection
Gontivimab (ALX-0171; VR-465) is a poent anti-RSV prefusion F protein nanobody with a K_D value of 0.113 nM. Gontivimab shows antiviral activity. Gontivimab reduces the RSV load in the nose and lung .

HY-P99804

Clesrovimab 3 Publications Verification MK1654	RSV	Infection
Clesrovimab (MK1654) is a humanized IgG1 monoclonal antibody targeting the respiratory syncytial virus (RSV) protein F. Clesrovimab binds to pre-fusion and post-fusion forms of RSV-A fusion protein with high affinity, with corresponding K_D values of 71 pM and 480 pM, respectively. Clesrovimab is applicable for the research of RSV infection .

HY-P991492

RSM-01	RSV	Infection
RSM-01 is a monoclonal antibody targeting site Ø of the pre-fusion F glycoprotein (Fusion glycoprotein F0) of respiratory syncytial virus (RSV). RSM-01 can be used in studies related to RSV infection .

HY-124512

Quercetin pentaacetate Pentaacetylquercetin	RSV	Infection Inflammation/Immunology
Quercetin pentaacetate could interact with F-protein with lower binding energy and better stability to block viral adhesion. Quercetin pentaacetate interacts with RSV and inhibit the viral adhesion on cell surface .

HY-N8448

3,4-Di-O-caffeoyl quinic acid methyl ester Macroantoin F	RSV	Infection
3,4-Di-O-caffeoyl quinic acid methyl ester (Macroantoin F) is a dicaffeoyl derivative isolated from the rhizome of Elephantopus scaber Linn. 3,4-Di-O-caffeoyl quinic acid methyl ester exhibited in vitro antiviral activity against respiratory syncytial virus (RSV)* with an IC₅₀ value of 0.78 μg/mL .*

HY-P991690

Glarivibart	RSV	Infection
Glarivibart is a humanized IgG1κ monoclonal antibody inhibitor targeting Respiratory syncytial virus (RSV) fusion F protein (RSV-F). Glarivibart has significant antiviral activity. Glarivibart can be used for RSV infections research .

HY-178151

CGR-50	RSV	Infection
CGR-50 is a potent RSV fusion glycoprotein (F protein) inhibitor (EC₅₀ = 32.6 nM against RSV A2 in HEp-2 cells). CGR-50 blocks RSV entry by binding to the F protein and inhibiting membrane fusion. CGR-50 can be used for RSV infection research .

HY-168616

CL-A3-7	RSV IGF-1R	Infection
CL-A3-7 is a virus-cell fusion inhibitor targeting the *RSV* F protein. It exerts its effect by blocking the interaction between the virus and the host IGF1R, effectively inhibiting infections of both wild-type *RSV* and the K394R variant. It is applicable to anti-RSV drug development and resistance-related research .

HY-P991157

Retavibart	RSV	Infection
Retavibart is a human respiratory syncytial virus (RSV) fusion glycoprotein F. Retavibart can be used for antiviral research. Isotype control: Human IgG1 kappa .

HY-P991495

VIR-8190	RSV	Infection
VIR-8190 is a human IgG1 monoclonal antibody (mAb) targeting F, Fusion glycoprotein F0. VIR-8190 can be used in respiratory syncytial virus (RSV) and metapneumovirus infections research. Recommended isotype control: Human IgG1 kappa, Isotype Control (HY-P99001).

HY-P992301

*Anti-RSV* F Antibody (R4.C6)**	RSV	Infection
Anti-RSV F Antibody (R4.C6) is a monoclonal antibody against RSV F, with a K_d of 0.34 nM for the post-fusion RSV F trimer. Anti-RSV F Antibody (R4.C6) recognizes a unique neutralizing epitope spanning epitopes II and IV on both pre-fusion and post-fusion RSV F. Anti-RSV F Antibody (R4.C6) can be used in studies related to respiratory syncytial virus infection .

HY-146108

RSV-IN-5	RSV	Infection
RSV-IN-5 (Compound 4) is a potent dual inhibitor of wild-type and mutant respiratory syncytial virus (RSV) fusion proteins. RSV-IN-5 exhibits potent anti-RSV activities against not only wild-type A2 F protein (EC₅₀=2.0 nM), but also D486N-mutant F protein (EC₅₀=8.1 nM) .

HY-P991494

IN-002	RSV	Infection
IN-002 is a human monoclonal antibody (mAb) targeting F, Fusion glycoprotein F0. IN-002 can be used in respiratory syncytial virus (RSV) infections research.

HY-P991499

EVO-46120	RSV	Infection
EVO-46120 is a human monoclonal antibody (mAb) targeting F, Fusion glycoprotein F0. EVO-46120 can be used in respiratory syncytial virus (RSV) and metapneumovirus infections research.

HY-P991493

AR-201	RSV	Infection
AR-201 is a human IgG1 monoclonal antibody (mAb) targeting F, Fusion glycoprotein F0. AR-201 has anti-respiratory syncytial virus (RSV) activity. AR-201 can be used in lower respiratory tract illness (LRTI) research. Recommended isotype control: Human IgG1 kappa, Isotype Control (HY-P99001).

HY-182030

RSV fusion protein IN-1	RSV	Infection
RSV fusion protein IN-1 is an orally active RSV pre-fusion F protein inhibitor with an IC₅₀ of 0.10 nM against RSV. RSV fusion protein IN-1 forms stable hydrogen bonds and π-π stacking interactions with pre-fusion F protein to block viral fusion and entry. RSV fusion protein IN-1 suppresses RSV F protein expression in epithelial cells. RSV fusion protein IN-1 reduces viral burden in the lungs of RSV-infected murine models.RSV fusion protein IN-1 can be used for the research of respiratory syncytial virus (RSV) infection .

HY-P992175

ADI-14448	RSV	Infection
ADI-14448 is a *RSV* prefusion fusion glycoprotein inhibitor and HMPV fusion glycoprotein inhibitor, with a K_d of 3.8 × 10 ^-10 M for *RSV* preF. ADI-14448 binds to epitope III of *RSV* preF, thereby blocking viral infection. ADI-14448 neutralizes *RSV* subtype A and HMPV subtype A1. ADI-14448 can be used in studies related to respiratory syncytial virus infection and metapneumovirus infection .

Cat. No.	Product Name	Target	Research Area	Image

HY-P9944

Palivizumab 3 Publications Verification MEDI 493	RSV	Infection Inflammation/Immunology Cancer
Palivizumab (MEDI 493) is a humanized monoclonal antibody against respiratory syncytial virus (RSV). Palivizumab can bind to RSV F protein with a K_d value of 1.4 nM. Palivizumab can prevent respiratory syncytial virus infection in cotton mice .

HY-P99647

Gontivimab ALX-0171; VR-465	RSV	Infection
Gontivimab (ALX-0171; VR-465) is a poent anti-RSV prefusion F protein nanobody with a K_D value of 0.113 nM. Gontivimab shows antiviral activity. Gontivimab reduces the RSV load in the nose and lung .

HY-P99804

Clesrovimab 3 Publications Verification MK1654	RSV	Infection
Clesrovimab (MK1654) is a humanized IgG1 monoclonal antibody targeting the respiratory syncytial virus (RSV) protein F. Clesrovimab binds to pre-fusion and post-fusion forms of RSV-A fusion protein with high affinity, with corresponding K_D values of 71 pM and 480 pM, respectively. Clesrovimab is applicable for the research of RSV infection .

HY-P991492

RSM-01	RSV	Infection
RSM-01 is a monoclonal antibody targeting site Ø of the pre-fusion F glycoprotein (Fusion glycoprotein F0) of respiratory syncytial virus (RSV). RSM-01 can be used in studies related to RSV infection .

HY-P991690

Glarivibart	RSV	Infection
Glarivibart is a humanized IgG1κ monoclonal antibody inhibitor targeting Respiratory syncytial virus (RSV) fusion F protein (RSV-F). Glarivibart has significant antiviral activity. Glarivibart can be used for RSV infections research .

HY-P991157

Retavibart	RSV	Infection
Retavibart is a human respiratory syncytial virus (RSV) fusion glycoprotein F. Retavibart can be used for antiviral research. Isotype control: Human IgG1 kappa .

HY-P991495

VIR-8190	RSV	Infection
VIR-8190 is a human IgG1 monoclonal antibody (mAb) targeting F, Fusion glycoprotein F0. VIR-8190 can be used in respiratory syncytial virus (RSV) and metapneumovirus infections research. Recommended isotype control: Human IgG1 kappa, Isotype Control (HY-P99001).

HY-P992301

*Anti-RSV* F Antibody (R4.C6)**	RSV	Infection
Anti-RSV F Antibody (R4.C6) is a monoclonal antibody against RSV F, with a K_d of 0.34 nM for the post-fusion RSV F trimer. Anti-RSV F Antibody (R4.C6) recognizes a unique neutralizing epitope spanning epitopes II and IV on both pre-fusion and post-fusion RSV F. Anti-RSV F Antibody (R4.C6) can be used in studies related to respiratory syncytial virus infection .

HY-P991494

IN-002	RSV	Infection
IN-002 is a human monoclonal antibody (mAb) targeting F, Fusion glycoprotein F0. IN-002 can be used in respiratory syncytial virus (RSV) infections research.

HY-P991499

EVO-46120	RSV	Infection
EVO-46120 is a human monoclonal antibody (mAb) targeting F, Fusion glycoprotein F0. EVO-46120 can be used in respiratory syncytial virus (RSV) and metapneumovirus infections research.

HY-P991493

AR-201	RSV	Infection
AR-201 is a human IgG1 monoclonal antibody (mAb) targeting F, Fusion glycoprotein F0. AR-201 has anti-respiratory syncytial virus (RSV) activity. AR-201 can be used in lower respiratory tract illness (LRTI) research. Recommended isotype control: Human IgG1 kappa, Isotype Control (HY-P99001).

HY-P992175

ADI-14448	RSV	Infection
ADI-14448 is a *RSV* prefusion fusion glycoprotein inhibitor and HMPV fusion glycoprotein inhibitor, with a K_d of 3.8 × 10 ^-10 M for *RSV* preF. ADI-14448 binds to epitope III of *RSV* preF, thereby blocking viral infection. ADI-14448 neutralizes *RSV* subtype A and HMPV subtype A1. ADI-14448 can be used in studies related to respiratory syncytial virus infection and metapneumovirus infection .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N8448

3,4-Di-O-caffeoyl quinic acid methyl ester Macroantoin F	Phenols Polyphenols Amorpha fruticosaL. Plants Compositae Source Classification	RSV
3,4-Di-O-caffeoyl quinic acid methyl ester (Macroantoin F) is a dicaffeoyl derivative isolated from the rhizome of Elephantopus scaber Linn. 3,4-Di-O-caffeoyl quinic acid methyl ester exhibited in vitro antiviral activity against respiratory syncytial virus (RSV)* with an IC₅₀ value of 0.78 μg/mL .*

Species:	Virus (5)
Tag:	His (4)
Source:	CHO (1) Sf9 insect cells (4)

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P705638

	Prefusion glycoprotein F Protein, HRSV (CHO) Human respiratory syncytial virus (RSV) (A2) Prefusion glycoprotein F/ RSV-preF Protein	Virus	CHO

HY-P75816

	Fusion glycoprotein F0/F Protein, HRSV (AFX60213, sf9, His) Human respiratory syncytial virus (RSV) Fusion protein / RSV-F Protein	Virus	Sf9 insect cells
	F0/F is a class of viral fusion proteins that, as an inactive precursor, are cleaved by a furfurin-like protease at two sites to produce mature F1 and F2 fusion glycoproteins.The F protein can mediate cell-cell fusion, lead to syncytial formation, and trigger p53-dependent apoptosis in the later stages of infection.Fusion glycoprotein F0/F Protein, HRSV (AFX60213, sf9, His) is the recombinant Virus-derived Fusion glycoprotein F0/F protein, expressed by Sf9 insect cells , with C-His labeled tag.

HY-P75817

	Fusion glycoprotein F0/F Protein, HRSV (AHX57537, sf9, His) Human respiratory syncytial virus (RSV) Fusion protein / RSV-F Protein	Virus	Sf9 insect cells
	F0/F is a class of viral fusion proteins that, as an inactive precursor, are cleaved by a furfurin-like protease at two sites to produce mature F1 and F2 fusion glycoproteins.The F protein can mediate cell-cell fusion, lead to syncytial formation, and trigger p53-dependent apoptosis in the later stages of infection.Fusion glycoprotein F0/F Protein, HRSV (AHX57537, sf9, His) is the recombinant Virus-derived Fusion glycoprotein F0/F protein, expressed by Sf9 insect cells , with C-His labeled tag.

HY-P75815

	Fusion glycoprotein F0/F Protein, HRSV (P11209, sf9, His) Human respiratory syncytial virus (RSV) Fusion protein / RSV-F (Strain RSS-2) Protein	Virus	Sf9 insect cells
	The fusion glycoprotein F0/F protein is cleaved to generate mature F1 and F2 fusion glycoproteins.It functions as a viral fusion protein, promoting the fusion of virus and cell membranes through different state transitions.Fusion glycoprotein F0/F Protein, HRSV (P11209, sf9, His) is the recombinant Virus-derived Fusion glycoprotein F0/F protein, expressed by Sf9 insect cells , with C-His labeled tag.

HY-P75182

	Fusion glycoprotein F0/F Protein, HRSV (sf9, His) Human respiratory syncytial virus Fusion glycoprotein/RSV-F Protein; F Protein; HRSVgp08 Protein	Virus	Sf9 insect cells
	The fusion glycoprotein F0/F protein is initially an inactive precursor that is cleaved by furin-like proteases to produce the mature F1 and F2 fusion glycoproteins.As a class I viral fusion protein, it undergoes prefusion, prehairpin, and postfusion states.Fusion glycoprotein F0/F Protein, HRSV (sf9, His) is the recombinant Virus-derived Fusion glycoprotein F0/F protein, expressed by Sf9 insect cells , with C-His labeled tag.

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RSV F

Inhibitors & Agonists

Inhibitory Antibodies

NaturalProducts

Recombinant Proteins

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Products