Quercetin pentaacetate
Quercetin pentaacetate could interact with F-protein with lower binding energy and better stability to block viral adhesion. Quercetin pentaacetate interacts with RSV and inhibit the viral adhesion on cell surface.
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- Purity: 96.50%
- CAS No.: 1064-06-8
- 화학식: C25H20O12
- 분자량:512.42
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보관:
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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Biological Activity
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Chemical Information
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용액&용해도
- 순도&문서
- References
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Help & FAQs
Biological Activity
제품 설명
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| J774.2 | IC50 |
109.23 μM
Compound: 2a
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Cytotoxicity against BALB/c mouse J774.2 cells after 72 hrs by trypan blue assay
Cytotoxicity against BALB/c mouse J774.2 cells after 72 hrs by trypan blue assay
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[PMID: 19489596] |
In Vitro
Quercetin pentaacetate (0-40 μM) shows the obvious inhibition on LPS-induced PGE2 production and COX-2 gene expression and the inhibition in NLA/LPS or L-NAME/LPS co-treated RAW 264.7 cells[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1064-06-8
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Appearance Solid
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분자량 512.42
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화학식 C25H20O12
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Color Off-white to light yellow
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SMILES
O=C1C(OC(C)=O)=C(C2=CC=C(OC(C)=O)C(OC(C)=O)=C2)OC3=CC(OC(C)=O)=CC(OC(C)=O)=C13
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Synonyms
Pentaacetylquercetin
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선적
Room temperature in continental US; may vary elsewhere.
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보관
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
용액&용해도
In Vitro:
DMSO : 30 mg/mL (58.55 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
순도&문서
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Data Sheet (275 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. Bruno Rafael Pereira Lopes, et al. Quercetin Pentaacetate Inhibits in Vitro Human Respiratory Syncytial Virus Adhesion. Virus Res. 2020 Jan 15;276:197805. [Content Brief]
[2]. Y C Chen, et al. Inhibition of Nitric Oxide Synthase Inhibitors and Lipopolysaccharide Induced Inducible NOS and cyclooxygenase-2 Gene Expressions by Rutin, Quercetin, and Quercetin Pentaacetate in RAW 264.7 Macrophages. J Cell Biochem. 2001;82(4):537-48. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.9515 mL | 9.7576 mL | 19.5152 mL | 48.7881 mL |
| 5 mM | 0.3903 mL | 1.9515 mL | 3.9030 mL | 9.7576 mL | |
| 10 mM | 0.1952 mL | 0.9758 mL | 1.9515 mL | 4.8788 mL | |
| 15 mM | 0.1301 mL | 0.6505 mL | 1.3010 mL | 3.2525 mL | |
| 20 mM | 0.0976 mL | 0.4879 mL | 0.9758 mL | 2.4394 mL | |
| 25 mM | 0.0781 mL | 0.3903 mL | 0.7806 mL | 1.9515 mL | |
| 30 mM | 0.0651 mL | 0.3253 mL | 0.6505 mL | 1.6263 mL | |
| 40 mM | 0.0488 mL | 0.2439 mL | 0.4879 mL | 1.2197 mL | |
| 50 mM | 0.0390 mL | 0.1952 mL | 0.3903 mL | 0.9758 mL |
Quercetin pentaacetate Related Classifications
HY-124512 Related Classifications
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