Prefusion glycoprotein F Protein, HRSV (CHO)
Based on 1 Customer Validation
Prefusion glycoprotein F, HRSV (CHO) is a recombinant prefusion glycoprotein F, HRSV expressed by CHO.
- Species: Virus
- Source: CHO
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Storage:Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Technical Parameters
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Product Properties
- Documentation
- Help & FAQs
Biological Activity
Description
Prefusion glycoprotein F, HRSV (CHO) is a recombinant prefusion glycoprotein F, HRSV expressed by CHO.
Background
Human respiratory syncytial virus (RSV) (hRSV) is the most frequent cause of severe lower respiratory tract infections (bronchiolitis and pneumonia) in infants and young children throughout the world. In addition, a Th2-biased CD4 T-cell response, characterized by the production of allergic inflammation, including interleukin-4 (IL-4) production, may also have contributed to the enhanced disease observed in the FI hRSV vaccine trial. However, disease enhancement is not observed with live attenuated hRSV strains or with subunit vaccines in individuals who have experienced previous RSV infections.
Verified Bioactivity
Immobilized Human respiratory syncytial virus (RSV) (A2) Prefusion glycoprotein F/ RSV-preF Protein at 0.5 μg/mL (100 μL/well) can bind RSV specific antibody which targets antigenic site II (Palivizumab), the EC50 is 1.0-2.0 ng/mL.
Technical Parameters
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Species Virus
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Source CHO
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Accession
Sequence information is not available or disclosed for this product.
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Gene ID/
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Synonyms
Human respiratory syncytial virus (RSV) (A2) Prefusion glycoprotein F/ RSV-preF Protein
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Predicted Molecular Mass
54.5 kDa
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Molecular Weight
Approximately 58 kDa, based on SDS-PAGE under reducing conditions.
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Purity
≥ 95%, as determined by reducing SDS-PAGE.
Product Properties
Solution
Lyophilized from a 0.22 μm filtered solution of 20 mM Sodium Citrate, 200 mM NaCl, 0.02% Tween-80, pH 6.0.
<1 EU/μg, determined by LAL method.
It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O. For long term storage it is recommended to add 5-50% of glycerol (final concentration). Our default final concentration of glycerol is 50%. Customers could use it as reference.
Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
Shipping with dry ice.
Documentation
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Data Sheet (232 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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