Search Result

Results for "

SCR

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Akt (1) Amyloid-β (1) Apoptosis (5) Bacterial (1) Bcr-Abl (1) c-Met/HGFR (2) Calcium Channel (1) CDK (1) Cholinesterase (ChE) (1) DNA/RNA Synthesis (3) Filovirus (2) Fungal (1) GLUT (1) GSK-3 (1) Hepatitis E Virus (HEV) (2) HIV (2) Methionine Adenosyltransferase (MAT) (1) NO Synthase (1) Parasite (1) Phosphatase (1) PIN1 (1) PKA (1) PROTAC Linkers (1) Reactive Oxygen Species (ROS) (2) Reference Standards (1) SARS-CoV (2) Small Interfering RNA (siRNA) (1) Src (2) Tau Protein (1) TREM receptor (1) VEGFR (2)
By Research Areas:	Cancer (10) Infection (5) Inflammation/Immunology (1) Metabolic Disease (2) Neurological Disease (3)
Click Chemistry:	PROTAC Synthesis (1) Alkynes (1)
Oligonucleotides:	Mouse Pre-designed siRNA Sets (1) siRNAs (1)

Inhibitors & Agonists

Peptides

Natural
Products

Antibodies

Click Chemistry

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-107845

SCR7 pyrazine Maximum Cited Publications 20 Publications Verification	DNA/RNA Synthesis Apoptosis	Cancer
SCR7 pyrazine is a DNA ligase IV inhibitor that blocks nonhomologous end-joining (NHEJ) in a ligase IV-dependent manner. SCR7 pyrazine increases the efficiency of Cas9-mediated homology-directed repair (HDR). SCR7 pyrazine induces cell apoptosis and has anticancer activity .

HY-P3211B

Nangibotide scrambled peptide 2 Publications Verification LR12-SCR	TREM receptor	Inflammation/Immunology
Nangibotide scrambled peptide (LR12-scr) is a scrambled control peptide composed of the same amino acids from LR12 (Nangibotide; HY-P3211) but in a random sequence (YQDVELCETGED) .

HY-18711A

SCR-1481B1 Metatinib anhydrous; c-Met inhibitor 2	c-Met/HGFR VEGFR	Cancer
SCR-1481B1 (Metatinib anhydrous) is a potent compound that has activity against cancers dependent upon Met activation and also has activity against cancers as a VEGFR inhibitor.

HY-139297

SCR130 1 Publications Verification	DNA/RNA Synthesis Apoptosis	Cancer
SCR130 is a SCR7-based DNA nonhomologous end-joining (NHEJ) inhibitor. SCR130 inhibits the end-joining of DNA in a Ligase IV-dependent manner. SCR130 is specific to Ligase IV, and shows minimal or no effect on Ligase III and Ligase I mediated joining. SCR130 induces cell apoptosis and has anticancer activity .

HY-169257

SCR-7952	Methionine Adenosyltransferase (MAT)	Cancer
SCR-7952 is a MAT2A inhibitor, with IC₅₀ of 18.7 nM. SCR-7952 can be used in anti-cancer research .

HY-N6924

Zingibroside R1 1 Publications Verification	HIV PIN1 Fungal GLUT Reactive Oxygen Species (ROS)	Infection Neurological Disease Metabolic Disease Cancer
Zingibroside R1 is an orally active triterpene saponin with multiple biological activities including antioxidant, anti-inflammatory, antiviral, and metabolic regulatory properties. Zingibroside R1 reduces the expression of PIN family members, inhibits the expression of PLT1/PLT2, WOX5, SHR, and *SCR, disrupts auxin transport and distribution, triggers plant ROS* responses, and inhibits root growth. Zingibroside R1 extends the lifespan of Caenorhabditis elegans, enhances its heat stress resistance, and improves its motor ability. Hydrogel derivatives of Zingibroside R1 inhibit the proliferation of Candida albicans by binding to its β-1,3-glucan and exhibit antifungal activity. Zingibroside R1 inhibits GLUT1-mediated uptake and alleviates liver injury. Zingibroside R1 can be used in research related to neurodegenerative diseases, vulvovaginal candidiasis, acute liver injury, Ehrlich ascites tumor and HIV-1 infection .

HY-175845

Scr-IN-2	Src Apoptosis Reactive Oxygen Species (ROS)	Cancer
Scr-IN-2 is an effective *c-Scr* inhibitor with an IC₅₀ of 302 nM. Scr-IN-2 exhibits nanomolar-level anti-breast cancer activity. Scr-IN-2 increases the level of ROS in cells, induces mitochondrial damage, G1 phase arrest, and apoptosis. Scr-IN-2 can be used in the research of breast cancer .

HY-178137

SCR007	SARS-CoV Hepatitis E Virus (HEV) Filovirus	Infection
SCR007 is a synthetic carbohydrate receptor (SCR) with broad-spectrum antiviral activity. SCR007 inhibits the entry of enveloped viruses across multiple families (Coronaviridae: SARS-CoV-1, SARS-CoV-2, MERS-CoV; Filoviridae: EBOV, MARV; Paramyxoviridae: NiV, HeV) and the glycosylated nonenveloped rotavirus. SCR007 binds viral envelope N-glycans, blocking viral binding to host cells or both binding and membrane fusion. SCR007 exerts prophylactic effects in hACE2 mice infected with SARS-CoV-2. SCR007 can be used for the study and prevention of enveloped virus pandemics .

HY-P4114

TAT-NSF700scr	HIV	Others
TAT-NSF700scr consists the intact TAT domain and glycine linker, followed by the NSF amino acids in a random order. TAT-NSF700scr is used as a control peptide that does not inhibit SNAREmediated exocytosis .

HY-18711

SCR-1481B1 free base Metatinib free base; c-Met inhibitor 2 free base	c-Met/HGFR VEGFR	Cancer
SCR-1481B1 free base, also known as Metatinib free base, is a small molecule receptor kinase inhibitor that targets both c-MET and vascular endothelial growth factor receptor 2 (VEGFR2) .

HY-112371

(S)-CR8	CDK	Cancer
(S)-CR8 is the S-isomer of CR8. (S)-CR8 is a potent and selective CDK inhibitor with IC₅₀s of 0.060, 0.080, 0.11, 0.12, and 0.15 μM for CDK2/cyclin E, CDK2/cyclin A, CDK9/cyclin T, CDK5/p25, and CDK1/cyclin B, respectively. (S)-CR8 reduces SH-SY5Y cells survival (IC₅₀ 0.40 μM) .

HY-178135

SCR005	SARS-CoV Filovirus Hepatitis E Virus (HEV)	Infection
SCR005 is a synthetic carbohydrate receptor (SCR) with broad-spectrum antiviral activity. SCR005 inhibits the entry of enveloped viruses across multiple families (Coronaviridae: SARS-CoV-1, SARS-CoV-2, MERS-CoV; Filoviridae: EBOV, MARV; Paramyxoviridae: NiV, HeV) and the glycosylated nonenveloped rotavirus. SCR005 binds viral envelope N-glycans, blocking viral binding to host cells or both binding and membrane fusion. SCR005 exerts prophylactic effects in hACE2 mice infected with SARS-CoV-2. SCR005 can be used for the study and prevention of enveloped virus pandemics .

HY-165341

SCR1693	Amyloid-β Cholinesterase (ChE) Calcium Channel GSK-3 Tau Protein Phosphatase Akt PKA	Neurological Disease Metabolic Disease
SCR1693 is a selective, reversible, orally active and noncompetitive inhibitor of AChE (IC₅₀ = 0.68 μM) as well as a calcium channel blocker. SCR1693 reduces tau phosphorylation levels, and inhibits the generation and release of Aβ. SCR1693 restores insulin signaling and improves cognitive deficits. SCR1693 can be used for the study of Alzheimer's disease, especially which complicated with type 2 diabetes mellitus .

HY-14142

AP-24226	Bcr-Abl	Others
AP-24226 is a potent inhibitor of *Scr/ABL* .

HY-100458

SCR-4026	NO Synthase	Neurological Disease
SCR-4026 is a neuroprotective agent with blood-brain barrier penetration ability. SCR-4026 exerts neuroprotective effects by disrupting the interaction between neuronal nNOS and PSD9, with an IC₅₀ of 6.3 μM. SCR-4026 alleviates N-methyl-D-aspartate (NMDA)-induced excitotoxic damage in primary cortical neurons, and also protects neurons in the oxygen-glucose deprivation (OGD) model. SCR-4026 can reduce the cerebral infarct volume in the rat middle cerebral artery occlusion (MCAO) reperfusion model. SCR-4026 can be used for the study of stroke .

HY-133193

Bis-propargyl-PEG5	PROTAC Linkers	Infection
Bis-propargyl-PEG5 is a PEG-based PROTAC linker used in the synthesis of PROTACs. Bis-propargyl-PEG5 is used for the synthesis of carbohydrate receptors (SCRs) with anti-Zika activity . Bis-propargyl-PEG5 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-170958

Scr-IN-1	Src Apoptosis	Cancer
Scr-IN-1 (Compound 4e) is a Tyrosine kinase inhibitor. Scr-IN-1 inhibits HCT-116 cells and MIA-PaCa-2 cells with IC₅₀s of 0.16 μM and 1.16 μM, respectively. Scr-IN-1 displays selectivity profile on HCT-116 cells and MIA-PaCa-2 cells with SI > 625 and SI > 86, respectively. Scr-IN-1 induces Apoptosis in HCT-116 colon cancer cell and does not cause any change in the rate of necrotic cells. Scr-IN-1 is a novel SRC kinase inhibitor candidate for HCT-116 cells. Scr-IN-1 is potential for cancer research .

HY-107845R

SCR7 pyrazine (Standard)	Reference Standards DNA/RNA Synthesis Apoptosis	Cancer
SCR7 pyrazine (Standard) is the analytical standard of SCR7 pyrazine (HY-107845). This product is intended for research and analytical applications. SCR7 pyrazine is a DNA ligase IV inhibitor that blocks nonhomologous end-joining (NHEJ) in a ligase IV-dependent manner. SCR7 pyrazine increases the efficiency of Cas9-mediated homology-directed repair (HDR). SCR7 pyrazine induces cell apoptosis and has anticancer activity .

HY-182711

SCR0911	Bacterial Parasite	Infection
SCR0911 is an inhibitor of mycobacterial cytochrome bcc oxidase and Plasmodium falciparum cytochrome bc1. SCR0911 disrupts oxidative phosphorylation by binding to mycobacterial cytochrome bcc, binds to the Qi site of Plasmodium falciparum cytochrome bc1, inhibits mycobacterial cell growth and ATP synthesis, and exhibits broad-spectrum anti-mycobacterial and anti-malarial activities. SCR0911 can be used in research related to tuberculosis, malaria, and isolated persistent hypermethioninemia (iph) .

HY-P11748

CBP-SCR

HY-RS19317

Dab1 Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Dab1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Dab1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Dab1 Mouse Pre-designed siRNA Set A Dab1 Mouse Pre-designed siRNA Set A

Cat. No.	Product Name	Target	Research Area

HY-P3211B

Nangibotide scrambled peptide 2 Publications Verification LR12-SCR	TREM receptor	Inflammation/Immunology
Nangibotide scrambled peptide (LR12-scr) is a scrambled control peptide composed of the same amino acids from LR12 (Nangibotide; HY-P3211) but in a random sequence (YQDVELCETGED) .

HY-P4114

TAT-NSF700scr	HIV	Others
TAT-NSF700scr consists the intact TAT domain and glycine linker, followed by the NSF amino acids in a random order. TAT-NSF700scr is used as a control peptide that does not inhibit SNAREmediated exocytosis .

HY-P4112

TAT-NSF222scr Fusion Polypeptide, scrambled	Peptides	Others
TAT-NSF222scr Fusion Polypeptide, scrambled is a control peptide of TAT-NSF700 Fusion Peptide (HY-P4113). TAT-NSF222scr Fusion Polypeptide, scrambled is consisted of the intact TAT domain followed by the amino acid residues of NSF 222-243 in a scrambled order .

HY-P11748

CBP-SCR

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N6924

Zingibroside R1 1 Publications Verification	Infection Structural Classification Panax notoginseng (Burkill) F. H. Chen ex C. H. Chow Classification of Application Fields Panax japonicas C. A. Mey. Metabolic Disease Plants Disease Research Fields Saccharides Araliaceae Source Classification	HIV PIN1 Fungal GLUT Reactive Oxygen Species (ROS)
Zingibroside R1 is an orally active triterpene saponin with multiple biological activities including antioxidant, anti-inflammatory, antiviral, and metabolic regulatory properties. Zingibroside R1 reduces the expression of PIN family members, inhibits the expression of PLT1/PLT2, WOX5, SHR, and *SCR, disrupts auxin transport and distribution, triggers plant ROS* responses, and inhibits root growth. Zingibroside R1 extends the lifespan of Caenorhabditis elegans, enhances its heat stress resistance, and improves its motor ability. Hydrogel derivatives of Zingibroside R1 inhibit the proliferation of Candida albicans by binding to its β-1,3-glucan and exhibit antifungal activity. Zingibroside R1 inhibits GLUT1-mediated uptake and alleviates liver injury. Zingibroside R1 can be used in research related to neurodegenerative diseases, vulvovaginal candidiasis, acute liver injury, Ehrlich ascites tumor and HIV-1 infection .

Host:	Mouse (2)
Reactivity:	Human (2) Rat (2) Mouse (2)
Application:	IHC-P (2)
Isotype:	IgG1 (2)
Conjugation:	Non-conjugated (2)
Clonality:	Monoclonal (1)
Modification:	Unmodified (1)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P88228

	RBMS1 Antibody (YA7912) C2orf12; HCC-4; MSSP; MSSP-1; MSSP-2; MSSP-3; SCR2; YC1	IHC-P	Human, Mouse, Rat
	RBMS1 Antibody (YA7912) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to RBMS1.

HY-P88228A

	RBMS1 Antibody (YA7912)(PBS only) C2orf12; HCC-4; MSSP; MSSP-1; MSSP-2; MSSP-3; SCR2; YC1	IHC-P	Human, Mouse, Rat
	RBMS1 Antibody (YA7912) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to RBMS1.

Compare Products


Products	In-stock - + Add to Cart
Cat. No.
Host
Reactivity
Application
Dilution Ratio
Molecular Weight
Conjugation
Clonality
Immunogen
Appearance
Isotype
Gene ID
SwissProt ID
Purity
Formulation
Free Sample	Yes No
Size	* This product has been "discontinued". Optimized version of product available: / In-stock - + Add to Cart Get quote

Cat. No.	Product Name		Classification

HY-133193

Bis-propargyl-PEG5		Alkynes PROTAC Synthesis
Bis-propargyl-PEG5 is a PEG-based PROTAC linker used in the synthesis of PROTACs. Bis-propargyl-PEG5 is used for the synthesis of carbohydrate receptors (SCRs) with anti-Zika activity . Bis-propargyl-PEG5 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Dab1 Mouse Pre-designed siRNA Set A		siRNAs Mouse Pre-designed siRNA Sets
Dab1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Dab1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Inquiry Online

Your information is safe with us. * Required Fields.

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社重松貿易株式会社
Salutation			Country or Region *
Applicant Name *			Organization Name *
Department *
Email Address *			Product Name *
Cat. No.			Requested quantity *
Phone Number *
Remarks