1. Cell Cycle/DNA Damage
  2. CDK
  3. (S)-CR8

(S)-CR8 

Cat. No.: HY-112371
Handling Instructions

(S)-CR8 is the S-isomer of CR8. (S)-CR8 is a potent and selective CDK inhibitor with IC50s of 0.060, 0.080, 0.11, 0.12, and 0.15 μM for CDK2/cyclin E, CDK2/cyclin A, CDK9/cyclin T, CDK5/p25, and CDK1/cyclin B, respectively. (S)-CR8 reduces SH-SY5Y cells survival (IC50 0.40 μM).

For research use only. We do not sell to patients.

(S)-CR8 Chemical Structure

(S)-CR8 Chemical Structure

CAS No. : 1084893-56-0

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Description

(S)-CR8 is the S-isomer of CR8. (S)-CR8 is a potent and selective CDK inhibitor with IC50s of 0.060, 0.080, 0.11, 0.12, and 0.15 μM for CDK2/cyclin E, CDK2/cyclin A, CDK9/cyclin T, CDK5/p25, and CDK1/cyclin B, respectively. (S)-CR8 reduces SH-SY5Y cells survival (IC50 0.40 μM)[1].

Molecular Weight

431.53

Formula

C24H29N7O

CAS No.
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(S)-CR8
Cat. No.:
HY-112371
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