1. Protein Tyrosine Kinase/RTK
  2. c-Met/HGFR
    VEGFR
  3. SCR-1481B1

SCR-1481B1 (Synonyms: c-Met inhibitor 2)

Cat. No.: HY-18711A Purity: 99.99%
Handling Instructions

SCR-1481B1 (c-Met inhibitor 2) is a potent compound that has activity against cancers dependent upon Met activation and also has activity against cancers as a VEGFR inhibitor.

For research use only. We do not sell to patients.

SCR-1481B1 Chemical Structure

SCR-1481B1 Chemical Structure

CAS No. : 1174161-86-4

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 203 In-stock
Estimated Time of Arrival: December 31
5 mg USD 132 In-stock
Estimated Time of Arrival: December 31
10 mg USD 228 In-stock
Estimated Time of Arrival: December 31
50 mg USD 780 In-stock
Estimated Time of Arrival: December 31
100 mg USD 1200 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

* Please select Quantity before adding items.

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Based on 1 publication(s) in Google Scholar

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  • Biological Activity

  • Technical Information

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  • References

Description

SCR-1481B1 (c-Met inhibitor 2) is a potent compound that has activity against cancers dependent upon Met activation and also has activity against cancers as a VEGFR inhibitor.

IC50 & Target[1]

VEGFR1

 

In Vitro

More details please refer to Patent WO 2009094417 A1.

Clinical Trial
Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : ≥ 31 mg/mL (44.29 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.4286 mL 7.1431 mL 14.2861 mL
5 mM 0.2857 mL 1.4286 mL 2.8572 mL
10 mM 0.1429 mL 0.7143 mL 1.4286 mL
*Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

699.98

Formula

C₂₈H₂₉ClF₂N₅O₁₀P

CAS No.

1174161-86-4

SMILES

O=C(C1=CN(COP(O)(O)=O)C=C(C2=CC=C(F)C=C2)C1=O)NC3=CC=C(OC4=C(Cl)C(N)=NC=C4)C(F)=C3.OCC(CO)(N)CO

Shipping

Room temperature in continental US; may vary elsewhere

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Product Name:
SCR-1481B1
Cat. No.:
HY-18711A
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SCR-1481B1

Cat. No.: HY-18711A