TAR

By Targets:	Antibiotic (5) Apoptosis (1) Bacterial (5) Biochemical Assay Reagents (1) DNA/RNA Synthesis (7) Drug Intermediate (1) E1/E2/E3 Enzyme (1) Environmental Pollutants (1) Fungal (1) HIV (2) IKK (1) Isotope-Labeled Compounds (3) MicroRNA (6) NF-κB (1) Pyroptosis (1) Reference Standards (2) Small Interfering RNA (siRNA) (3)
By Research Areas:	Cancer (7) Infection (6) Inflammation/Immunology (2)
Oligonucleotides:	Human Pre-designed siRNA Sets (3) siRNAs (3)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-110261

GS143 2 Publications Verification	IKK E1/E2/E3 Enzyme NF-κB	Inflammation/Immunology
GS143 is a selective IκBα ubiquitination inhibitor with an IC₅₀ of 5.2 μM for SCF ^βTrCP1-mediated IκBα ubiquitylation. GS143 suppresses NF-κB activation and transcription of target genes and does not inhibit proteasome activity. GS143 has anti-asthma effect .

HY-W004842

Benzofuran-2-carboxaldehyde	Fungal	Others
Benzofuran-2-carboxaldehyde is a benzofuran derivative with a bitter almond odor. Benzofuran-2-carboxaldehyde exhibits high antifungal activity .

HY-B0268A

Enoxacin hydrate 2 Publications Verification Enoxacin sesquihydrate; AT-2266 hydrate; CI-919 hydrate	Bacterial DNA/RNA Synthesis MicroRNA Antibiotic	Infection Cancer
Enoxacin hydrate (Enoxacin sesquihydrate), a fluoroquinolone, interferes with DNA replication and inhibits bacterial DNA gyrase (IC₅₀=126 µg/ml) and topoisomerase IV (IC₅₀=26.5 µg/ml). Enoxacin hydrate is a miRNA processing activator and enhances siRNA-mediated mRNA degradation and promotes the biogenesis of endogenous miRNAs. Enoxacin hydrate has potent activities against gram-positive and -negative bacteria. Enoxacin hydrate is a cancer-specific growth inhibitor that acts by enhancing TAR RNA-binding protein 2 (TRBP)-mediated microRNA processing .

HY-B0268

Enoxacin 2 Publications Verification AT 2266; CI 919	Bacterial DNA/RNA Synthesis MicroRNA Antibiotic	Infection Cancer
Enoxacin (AT 2266), a fluoroquinolone, interferes with DNA replication and inhibits bacterial DNA gyrase (IC₅₀=126 µg/ml) and topoisomerase IV (IC₅₀=26.5 µg/ml). Enoxacin is a miRNA processing activator and enhances siRNA-mediated mRNA degradation and promotes the biogenesis of endogenous miRNAs. Enoxacin has potent activities against gram-positive and -negative bacteria. Enoxacin is a cancer-specific growth inhibitor that acts by enhancing TAR RNA-binding protein 2 (TRBP)-mediated microRNA processing .

HY-W013570

Acenaphthylene 1 Publications Verification	Environmental Pollutants Drug Intermediate	Others
Acenaphthylene is a polycyclic aromatic hydrocarbon (PAH). PAHs are derived naturally from coal and tar deposits, and produced by incomplete combustion of organic matter .

HY-147918

Anticancer agent 73	DNA/RNA Synthesis	Cancer
Anticancer agent 73 (compound CIB-3b) is a anticancer agent, potently targeting TAR RNA-binding protein 2 (TRBP) and disrupts its interaction with Dicer. Anticancer agent 73 can rebalance the expression profile of oncogenic or tumor-suppressive miRNAs. Anticancer agent 73 suppresses the proliferation and metastasis of HCC in vitro and in vivo .

HY-W087905

2,3-Dimethyl-2,3-diphenylbutane	Biochemical Assay Reagents	Others
2,3-Dimethyl-2,3-diphenylbutane is a minor product formed during the thermal decomposition of dicumyl peroxide (DCP) in cumene, generated through radical coupling reactions. As an initiator capable of producing free radicals, 2,3-dimethyl-2,3-diphenylbutane promotes cross-linking or decomposition processes via initiating free radical reactions in fields such as polymer polymerization (e.g., modification of polyphenylene oxide processing), organic synthesis (e.g., DCP decomposition reactions), and coal processing (e.g., oxidation stabilization of coal tar pitch), thereby enhancing material properties or reaction efficiency .

HY-W013570S

Acenaphthylene-d8 Acenaphthylene-d₈	Isotope-Labeled Compounds	Others
Acenaphthylene-d₈ is the deuterium labeled Acenaphthylene . Acenaphthylene is a polycyclic aromatic hydrocarbon (PAH). PAHs are derived naturally from coal and tar deposits, and produced by incomplete combustion of organic matter .

HY-B0268S1

Enoxacin-d8 hydrochloride	Isotope-Labeled Compounds Bacterial DNA/RNA Synthesis MicroRNA Antibiotic	Infection Cancer
Enoxacin-d₈ (hydrochloride) is deuterium labeled Enoxacin. Enoxacin (AT 2266), a fluoroquinolone, interferes with DNA replication and inhibits bacterial DNA gyrase (IC₅₀=126 μg/ml) and topoisomerase IV (IC₅₀=26.5 μg/ml). Enoxacin is a miRNA processing activator and enhances siRNA-mediated mRNA degradation and promotes the biogenesis of endogenous miRNAs. Enoxacin has potent activities against gram-positive and -negative bacteria. Enoxacin is a cancer-specific growth inhibitor that acts by enhancing TAR RNA-binding protein 2 (TRBP)-mediated microRNA processing .

HY-146382

WRNA10	HIV	Inflammation/Immunology
WRNA10 is a potent HIV-1 TAR RNA binder with an IC₅₀ of 10 µM and an CC₅₀ of 40 µM .

HY-RS14211

TARS3 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
TARS3 Human Pre-designed siRNA Set A contains three designed siRNAs for TARS3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

TARS3 Human Pre-designed siRNA Set A TARS3 Human Pre-designed siRNA Set A

HY-RS14210

TARS2 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
TARS2 Human Pre-designed siRNA Set A contains three designed siRNAs for TARS2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

TARS2 Human Pre-designed siRNA Set A TARS2 Human Pre-designed siRNA Set A

HY-W013570R

Acenaphthylene (Standard)	Reference Standards Others	Others
Acenaphthylene (Standard) is the analytical standard of Acenaphthylene. This product is intended for research and analytical applications. Acenaphthylene is a polycyclic aromatic hydrocarbon (PAH). PAHs are derived naturally from coal and tar deposits, and produced by incomplete combustion of organic matter .

HY-RS11759

RBM8A Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
RBM8A Human Pre-designed siRNA Set A contains three designed siRNAs for RBM8A gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

RBM8A Human Pre-designed siRNA Set A RBM8A Human Pre-designed siRNA Set A

HY-B0268S2

Enoxacin-d8 hydrate	Isotope-Labeled Compounds Antibiotic MicroRNA DNA/RNA Synthesis Bacterial	Infection Cancer
Enoxacin-d₈ (hydrate) is deuterium labeled Enoxacin. Enoxacin (AT 2266), a fluoroquinolone, interferes with DNA replication and inhibits bacterial DNA gyrase (IC₅₀=126 μg/ml) and topoisomerase IV (IC₅₀=26.5 μg/ml). Enoxacin is a miRNA processing activator and enhances siRNA-mediated mRNA degradation and promotes the biogenesis of endogenous miRNAs. Enoxacin has potent activities against gram-positive and -negative bacteria. Enoxacin is a cancer-specific growth inhibitor that acts by enhancing TAR RNA-binding protein 2 (TRBP)-mediated microRNA processing .

HY-B0268AR

Enoxacin hydrate (Standard) Enoxacin sesquihydrate (Standard); AT-2266 hydrate (Standard); CI-919 hydrate (Standard)	Reference Standards Bacterial DNA/RNA Synthesis MicroRNA Antibiotic	Infection Cancer
Enoxacin (hydrate) (Standard) is the analytical standard of Enoxacin (hydrate). This product is intended for research and analytical applications. Enoxacin hydrate (Enoxacin sesquihydrate), a fluoroquinolone, interferes with DNA replication and inhibits bacterial DNA gyrase (IC50=126 μg/ml) and topoisomerase IV (IC50=26.5 μg/ml). Enoxacin hydrate is a miRNA processing activator and enhances siRNA-mediated mRNA degradation and promotes the biogenesis of endogenous miRNAs. Enoxacin hydrate has potent activities against gram-positive and -negative bacteria. Enoxacin hydrate is a cancer-specific growth inhibitor that acts by enhancing TAR RNA-binding protein 2 (TRBP)-mediated microRNA processing [4].

HY-172885

TRBP-IN-1	DNA/RNA Synthesis MicroRNA Apoptosis Pyroptosis	Cancer
TRBP-IN-1 (Compound 13j) is an orally active TAR RNA binding protein 2 (TRBP) inhibitor (IC₅₀: 12.72 μM). TRBP-IN-1 has significant anti-hepatocellular carcinoma (HCC) activity and can inhibit the proliferation and metastasis of HCC cells (HCCLM3 cells (IC₅₀: 18.96 μM); SK-Hep-1 cells (IC₅₀: 16.45 μM)). TRBP-IN-1 regulates miRNA biogenesis and inhibits oncogenic miRNA expression by targeting TRBP. TRBP-IN-1 induces apoptosis and pyroptosis in HCC cells by inhibiting the level of miRNA. TRBP-IN-1 can be used for targeted therapy research of HCC .

HY-180187

019854-B06	HIV	Infection
019854-B06 is a potent inhibitor of Tat-mediated HIV-1 transcription (IC₅₀ = 1.44 μM), exhibiting antiviral activity against HIV-1 (EC₅₀ = 0.83 μM). 019854-B06 binds to Tat peptide (K_D = 33.5 μM), but not to TAR RNA. 019854-B06 neither promotes Tat degradation nor disrupts the Tat/CycT1 complex, supporting a Tat-centric, nondegradative mechanism .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-W013570

Acenaphthylene 1 Publications Verification	Structural Classification Natural Products other families Classification of Application Fields Other Diseases Plants Disease Research Fields Source Classification	Environmental Pollutants Drug Intermediate
Acenaphthylene is a polycyclic aromatic hydrocarbon (PAH). PAHs are derived naturally from coal and tar deposits, and produced by incomplete combustion of organic matter .

HY-W013570R

Acenaphthylene (Standard)	Structural Classification Natural Products other families Plants Source Classification	Reference Standards Others
Acenaphthylene (Standard) is the analytical standard of Acenaphthylene. This product is intended for research and analytical applications. Acenaphthylene is a polycyclic aromatic hydrocarbon (PAH). PAHs are derived naturally from coal and tar deposits, and produced by incomplete combustion of organic matter .

Species:	Human (2)
Tag:	His (1) Tag Free (1)
Source:	E. coli (2)

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P71788

	TARDBP Protein, Human (His) 1 Publications Verification ALS10; TAR DNA binding protein 43; TAR DNA binding protein; TAR DNA-binding protein 43; TARDBP; TDP 43; TDP-43; TDP43	Human	E. coli
	TARDBP protein is an RNA-binding factor with RRM1 and RRM2 that binds GU repeats and regulates RNA splicing in long introns and 3'UTRs.It affects proteins critical for neuronal survival and neurodegenerative diseases.TARDBP Protein, Human (His) is the recombinant human-derived TARDBP protein, expressed by E. coli , with N-6*His labeled tag.

HY-P705997

	LRRFIP1 Protein, Human LRRFIP1; Leucine-rich repeat flightless-interacting protein 1; LRR FLII-interacting protein 1; GC-binding factor 2; TAR RNA-interacting protein	Human	E. coli
	LRRFIP1 is a transcriptional repressor that preferentially binds to GC-rich sequences (5'-AGCCCCCGGCG-3') and may regulate the expression of TNF, EGFR, and PDGFA. It inhibits PDGFA, which controls smooth muscle cell proliferation after arterial injury. LRRFIP1 Protein, Human is the recombinant human-derived LRRFIP1 protein, expressed by E. coli.

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Cat. No.	Product Name	Chemical Structure

HY-W013570S

Acenaphthylene-d8
Acenaphthylene-d₈ is the deuterium labeled Acenaphthylene . Acenaphthylene is a polycyclic aromatic hydrocarbon (PAH). PAHs are derived naturally from coal and tar deposits, and produced by incomplete combustion of organic matter .

HY-B0268S1

Enoxacin-d8 hydrochloride
Enoxacin-d₈ (hydrochloride) is deuterium labeled Enoxacin. Enoxacin (AT 2266), a fluoroquinolone, interferes with DNA replication and inhibits bacterial DNA gyrase (IC₅₀=126 μg/ml) and topoisomerase IV (IC₅₀=26.5 μg/ml). Enoxacin is a miRNA processing activator and enhances siRNA-mediated mRNA degradation and promotes the biogenesis of endogenous miRNAs. Enoxacin has potent activities against gram-positive and -negative bacteria. Enoxacin is a cancer-specific growth inhibitor that acts by enhancing TAR RNA-binding protein 2 (TRBP)-mediated microRNA processing .

Enoxacin-d8 hydrochloride

Enoxacin-d₈ (hydrochloride) is deuterium labeled Enoxacin. Enoxacin (AT 2266), a fluoroquinolone, interferes with DNA replication and inhibits bacterial DNA gyrase (IC₅₀=126 μg/ml) and topoisomerase IV (IC₅₀=26.5 μg/ml). Enoxacin is a miRNA processing activator and enhances siRNA-mediated mRNA degradation and promotes the biogenesis of endogenous miRNAs. Enoxacin has potent activities against gram-positive and -negative bacteria. Enoxacin is a cancer-specific growth inhibitor that acts by enhancing TAR RNA-binding protein 2 (TRBP)-mediated microRNA processing .

HY-B0268S2

Enoxacin-d8 hydrate
Enoxacin-d₈ (hydrate) is deuterium labeled Enoxacin. Enoxacin (AT 2266), a fluoroquinolone, interferes with DNA replication and inhibits bacterial DNA gyrase (IC₅₀=126 μg/ml) and topoisomerase IV (IC₅₀=26.5 μg/ml). Enoxacin is a miRNA processing activator and enhances siRNA-mediated mRNA degradation and promotes the biogenesis of endogenous miRNAs. Enoxacin has potent activities against gram-positive and -negative bacteria. Enoxacin is a cancer-specific growth inhibitor that acts by enhancing TAR RNA-binding protein 2 (TRBP)-mediated microRNA processing .

Enoxacin-d8 hydrate

Enoxacin-d₈ (hydrate) is deuterium labeled Enoxacin. Enoxacin (AT 2266), a fluoroquinolone, interferes with DNA replication and inhibits bacterial DNA gyrase (IC₅₀=126 μg/ml) and topoisomerase IV (IC₅₀=26.5 μg/ml). Enoxacin is a miRNA processing activator and enhances siRNA-mediated mRNA degradation and promotes the biogenesis of endogenous miRNAs. Enoxacin has potent activities against gram-positive and -negative bacteria. Enoxacin is a cancer-specific growth inhibitor that acts by enhancing TAR RNA-binding protein 2 (TRBP)-mediated microRNA processing .

Host:	Mouse (2) Rabbit (6)
Reactivity:	Human (8) Rat (4) Mouse (7)
Application:	IHC-P (5) ICC/IF (3) IP (3) WB (8) FC (1) ELISA (2)
Isotype:	IgG (6)
Conjugation:	Non-conjugated (8)
Clonality:	Polyclonal (2) Monoclonal (5) Recombinant (1)
Modification:	Phosphorylated (3) Unmodified (4)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P85550

	LRRFIP1 Antibody (YA5242) FLAP1; FLIIAP 1; GC binding factor 2; GCF2; HUFI1; Leucine rich repeat; in FLII; interacting protein 1; Leucine rich repeat flightless interacting protein 1; LRR FLII interacting protein 1; LRRFIP 1; Lrrfip1; MGC10947; MGC119738; MGC119739; NEDD8 conjugating enzyme; TAR RNA interacting protein; TAR RNA-interacting protein; Transcription factor 9 like; TRIP.	WB	Human, Mouse
	LRRFIP1 Antibody (YA5242) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to LRRFIP1.

HY-P85441

	LRRFIP1 Antibody (YA5133) LRRFIP1; GCF2; TRIP; Leucine-rich repeat flightless-interacting protein 1; LRR FLII-interacting protein 1; GC-binding factor 2; TAR RNA-interacting protein	WB	Human
	LRRFIP1 Antibody (YA5133) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to LRRFIP1.

HY-P80759

	mTOR Antibody 1 Publications Verification MTOR; FRAP; FRAP1; FRAP2; RAFT1; RAPT1; Serine/threonine-protein kinase mTOR; FK506-binding protein 12-rapamycin complex-associated protein 1; FKBP12-rapamycin complex-associated protein; Mammalian TARget of rapamycin; mTOR; Mechanistic TAR	WB, IHC-P, ICC/IF, IP, FC	Human, Mouse, Rat
	mTOR Antibody is a Rabbit-derived and non-conjugated IgG polyclonal antibody, targeting to mTOR.

HY-P80838

	Phospho-mTOR (Ser2481) Antibody MTOR; FRAP; FRAP1; FRAP2; RAFT1; RAPT1; Serine/threonine-protein kinase mTOR; FK506-binding protein 12-rapamycin complex-associated protein 1; FKBP12-rapamycin complex-associated protein; Mammalian TARget of rapamycin; mTOR; Mechanistic TAR	WB	Human, Mouse, Rat
	Phospho-mTOR (Ser2481) Antibody is a Rabbit-derived and non-conjugated IgG polyclonal antibody, targeting to Phospho-mTOR (Ser2481).

HY-P86389

	mTOR Antibody (YA6081) MTOR; FRAP; FRAP1; FRAP2; RAFT1; RAPT1; Serine/threonine-protein kinase mTOR; FK506-binding protein 12-rapamycin complex-associated protein 1; FKBP12-rapamycin complex-associated protein; Mammalian TARget of rapamycin; mTOR; Mechanistic TAR	WB, IHC-P, ICC/IF, IP, ELISA	Human, Mouse, Rat
	mTOR Antibody (YA6081) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to mTOR.

HY-P80837

	Phospho-mTOR (Ser2448) Antibody (YA171) 2 Publications Verification MTOR; FRAP; FRAP1; FRAP2; RAFT1; RAPT1; Serine/threonine-protein kinase mTOR; FK506-binding protein 12-rapamycin complex-associated protein 1; FKBP12-rapamycin complex-associated protein; Mammalian TARget of rapamycin; mTOR; Mechanistic TAR	WB, IHC-P	Human, Mouse
	Phospho-mTOR (Ser2448) Antibody (YA171) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Phospho-mTOR (Ser2448).

HY-P86383

	Phospho-mTOR(Ser2448) Antibody (YA6075) MTOR; FRAP; FRAP1; FRAP2; RAFT1; RAPT1; Serine/threonine-protein kinase mTOR; FK506-binding protein 12-rapamycin complex-associated protein 1; FKBP12-rapamycin complex-associated protein; Mammalian TARget of rapamycin; mTOR; Mechanistic TAR	WB, IHC-P, ICC/IF, IP, ELISA	Human, Mouse, Rat
	Phospho-mTOR(Ser2448) Antibody (YA6075) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Phospho-mTOR(Ser2448).

HY-P80837A

	Phospho-mTOR (Ser2448) Antibody (YA171)(PBS only) MTOR; FRAP; FRAP1; FRAP2; RAFT1; RAPT1; Serine/threonine-protein kinase mTOR; FK506-binding protein 12-rapamycin complex-associated protein 1; FKBP12-rapamycin complex-associated protein; Mammalian TARget of rapamycin; mTOR; Mechanistic TAR	WB, IHC-P	Human, Mouse
	Phospho-mTOR (Ser2448) Antibody (YA171) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Phospho-mTOR (Ser2448).

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Cat. No.	Product Name		Classification

HY-RS14211

TARS3 Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
TARS3 Human Pre-designed siRNA Set A contains three designed siRNAs for TARS3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS14210

TARS2 Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
TARS2 Human Pre-designed siRNA Set A contains three designed siRNAs for TARS2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS11759

RBM8A Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
RBM8A Human Pre-designed siRNA Set A contains three designed siRNAs for RBM8A gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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