2,3-Dimethyl-2,3-diphenylbutane
Based on 1 Customer Validation
2,3-Dimethyl-2,3-diphenylbutane is a minor product formed during the thermal decomposition of dicumyl peroxide (DCP) in cumene, generated through radical coupling reactions. As an initiator capable of producing free radicals, 2,3-dimethyl-2,3-diphenylbutane promotes cross-linking or decomposition processes via initiating free radical reactions in fields such as polymer polymerization (e.g., modification of polyphenylene oxide processing), organic synthesis (e.g., DCP decomposition reactions), and coal processing (e.g., oxidation stabilization of coal tar pitch), thereby enhancing material properties or reaction efficiency.
For research use only. We do not sell to patients.
- Purity: 98.79%
- CAS No.: 1889-67-4
- Formula: C18H22
- Molecular Weight:238.37
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
2,3-Dimethyl-2,3-diphenylbutane plays a key role as an initiator in the preparation of diallyl orthophthalate (DAOP) prepolymers. The polymerization initiated by 2,3-Dimethyl-2,3-diphenylbutane can effectively improve the processability of thermoplastics by regulating the molecular weight and cross-linking density, while balancing the mechanical and thermodynamic properties of the materials[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1889-67-4
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Appearance Solid
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Molecular Weight 238.37
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Formula C18H22
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Color Off-white to yellow
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SMILES
CC(C)(C1=CC=CC=C1)C(C)(C2=CC=CC=C2)C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 25 mg/mL (104.88 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Select the appropriate dissolution method based on your experimental animal and administration route.
- For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
- To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
- The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: 10% DMSO 90% (20% SBE-β-CD in Saline)
Solubility: 2.5 mg/mL (10.49 mM); Suspended solution; Need ultrasonic
This protocol yields a suspended solution of 2.5 mg/mL. Suspended solution can be used for oral and intraperitoneal injection.
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.
Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
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%DMSO +
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
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%+
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+%Tween-80 + +
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%Saline +
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Working solution concentration: 0.22 mg/mL
Method for preparing stock solution: mg drug dissolved in μL DMSO. Stock solution concentration: mg/mL.
1. Take μL DMSO stock solution;
2. Add μL .
μL , mix evenly;
3. Then add μL Tween 80, mix evenly;
4. Then add μL
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
Purity & Documentation
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Data Sheet (275 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
[1]. Di Somma I, et al. Kinetic and chemical characterization of thermal decomposition of dicumylperoxide in cumene. J Hazard Mater. 2011;187(1-3):157-163. [Content Brief]
[2]. Wang H, et al. Improved Processing and Properties for Polyphenylene Oxide Modified by Diallyl Orthophthalate Prepolymer. Polymers (Basel). 2019;11(12):2016. Published 2019 Dec 5. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.1952 mL | 20.9758 mL | 41.9516 mL | 104.8790 mL |
| 5 mM | 0.8390 mL | 4.1952 mL | 8.3903 mL | 20.9758 mL | |
| 10 mM | 0.4195 mL | 2.0976 mL | 4.1952 mL | 10.4879 mL | |
| 15 mM | 0.2797 mL | 1.3984 mL | 2.7968 mL | 6.9919 mL | |
| 20 mM | 0.2098 mL | 1.0488 mL | 2.0976 mL | 5.2439 mL | |
| 25 mM | 0.1678 mL | 0.8390 mL | 1.6781 mL | 4.1952 mL | |
| 30 mM | 0.1398 mL | 0.6992 mL | 1.3984 mL | 3.4960 mL | |
| 40 mM | 0.1049 mL | 0.5244 mL | 1.0488 mL | 2.6220 mL | |
| 50 mM | 0.0839 mL | 0.4195 mL | 0.8390 mL | 2.0976 mL | |
| 60 mM | 0.0699 mL | 0.3496 mL | 0.6992 mL | 1.7480 mL | |
| 80 mM | 0.0524 mL | 0.2622 mL | 0.5244 mL | 1.3110 mL | |
| 100 mM | 0.0420 mL | 0.2098 mL | 0.4195 mL | 1.0488 mL |
2,3-Dimethyl-2,3-diphenylbutane Related Classifications
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