LRRFIP1 Antibody (YA5133)

Cat. No.: HY-P85441: Data Sheet User Guide for Antibodies
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LRRFIP1 Antibody (YA5133) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to LRRFIP1.

For research use only. We do not sell to patients.

Size		Stock
50 μL		Get quote
100 μL		Get quote

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

LRRFIP1 Antibody (YA5133) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to LRRFIP1.

Host

Mouse

Clonality

Monoclonal

Molecular Weight

Predicted band size: 89 kDa;

Species Reactivity

Human

SwissProt ID

Q32MZ4

Gene ID

9208 [NCBI]

Immunogen

Purified recombinant human LRRFIP1 protein fragments expressed in E.coli.

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:1000-1:2000

Purity	affinity purified.	Conjugation	Non-conjugated
Modification	Unmodified

Appearance

Liquid

Formulation

Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Transcriptional repressor which preferentially binds to the GC-rich consensus sequence (5'-AGCCCCCGGCG-3') and may regulate expression of TNF, EGFR and PDGFA. May control smooth muscle cells proliferation following artery injury through PDGFA repression. May also bind double-stranded RNA. Positively regulates Toll-like receptor (TLR) signaling in response to agonist probably by competing with the negative FLII regulator for MYD88-binding

Subcellular Localization：Nucleus; Cytoplasm

Expression：
Tissue_specificity:general expression

Isoforms & Post-Translational Modification：Q32MZ4 has 4 isomers: Q32MZ4-1: 89253 Da (predicted); Q32MZ4-2: 86404 Da (predicted); Q32MZ4-3: 82689 Da (predicted); Q32MZ4-4: 73060 Da (predicted).

Subunit：Homodimer. May also form higher oligomers. Interacts with FLII. Interacts with MYD88. Competes with FLII for MyD88-binding, even in the absence of LPS

Synonyms

LRRFIP1; GCF2; TRIP; Leucine-rich repeat flightless-interacting protein 1; LRR FLII-interacting protein 1; GC-binding factor 2; TAR RNA-interacting protein

Documentation

User Guide for Antibodies (1077 KB)