WRNA10
WRNA10 is a potent HIV-1 TAR RNA binder with an IC50 of 10 µM and an CC50 of 40 µM.
For research use only. We do not sell to patients.
- CAS No.: 1174719-68-6
- Formula: C25H32N4O4
- Molecular Weight:452.55
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
IC50 & Target
[1]|
HIV 10 μM (IC50, CC50: 40 μM[1]) |
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| Vero C1008 | CC50 |
40 μM
Compound: WRNA10
|
Cytotoxicity against African green monkey Vero E6 cells assessed as reduction in cell viability measured after 1 to 2 hrs by MTS colorimetric assay
Cytotoxicity against African green monkey Vero E6 cells assessed as reduction in cell viability measured after 1 to 2 hrs by MTS colorimetric assay
|
[PMID: 35571875] |
Chemical Information
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CAS No. 1174719-68-6
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Molecular Weight 452.55
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Formula C25H32N4O4
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SMILES
COC1=CC(O)=C2C(C=C(N(C2=C1)C)C3=CC=C(C(N)=C3)OCCCN4CCN(CC4)C)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)