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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
21 Results for "
TGFβ3
" in MedChemExpress (MCE) Product Catalog:
Products (21)
21 Results for "TGFβ3" in MCE Product Catalog:
8
8 Publications Verification
Cat. No.: HY-P7120
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TGFB3; Transforming Growth Factor, Beta 3; Prev. ARVD1; Transforming Growth Factor Beta; Prev. ARVD; TGF-Beta3; Transforming Growth Factor Beta-3 Proprotein; LDS5; Prepro-Transforming Growth Factor Beta-3; RNHF; Arrhythmogenic Right Ventricular Dysplasia
2
2 Cited Publications
Cat. No.: HY-19767
CAS No.: 1629249-33-7
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GSK 3008348 is a small molecule antagonist of integrin αvβ6 with IC50 values for αvβ6, αvβ1, αvβ3, αvβ5, and αvβ8 are 1.50, 2.83, 12.53, 4.00, and 2.26 nM, respectively. GSK 3008348 can target the αvβ6 integrin, inhibit TGF-β activation, and thereby alleviate the fibrotic process. GSK 3008348 prevents the binding of the foot-and-mouth disease virus (FMDV) to the αvβ6 integrin receptor on the surface of host cells, thereby inhibiting the entry of the virus. GSK 3008348 can be used for research on pulmonary fibrosis and various types of cancer [3] .
2
2 Cited Publications
Cat. No.: HY-19767A
CAS No.: 1629249-40-6
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GSK 3008348 hydrochloride is a small molecule antagonist of integrin αvβ6 with IC50 values for αvβ6, αvβ1, αvβ3, αvβ5, and αvβ8 are 1.50, 2.83, 12.53, 4.00, and 2.26 nM, respectively. GSK 3008348 hydrochloride can target the αvβ6 integrin, inhibit TGF-β activation, and thereby alleviate the fibrotic process. GSK 3008348 hydrochloride prevents the binding of the foot-and-mouth disease virus (FMDV) to the αvβ6 integrin receptor on the surface of host cells, thereby inhibiting the entry of the virus. GSK 3008348 hydrochloride can be used for research on pulmonary fibrosis and various types of cancer [3].
1
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Selvigaltin (GB1211) is an orally active galectin-3 small molecule inhibitor with an IC50 value of 12 nM in rabbits, showing anti-tumor activity. Selvigaltin decreases galectin-3 levels in the liver and reduces biomarkers of liver function (AST, ALT, bilirubin), inflammation (cells foci) and fibrosis (PSR, SHG), as well as decreasing the mRNA and protein expression of several key inflammation and fibrosis biomarkers (IL6, TGFβ3, SNAI2, collagen). Selvigaltin restores T-cell activity and induces less tumors and metastasis [3] .
1
1 Cited Publications
Cat. No.: HY-P700152AF
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TGFB3; Transforming Growth Factor, Beta 3; Prev. ARVD1; Transforming Growth Factor Beta; Prev. ARVD; TGF-Beta3; Transforming Growth Factor Beta-3 Proprotein; LDS5; Prepro-Transforming Growth Factor Beta-3; RNHF; Arrhythmogenic Right Ventricular Dysplasia
Cat. No.: HY-135582
CAS No.: 182507-22-8
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Raloxifene 4'-glucuronide is a primary metabolite of Raloxifene. Raloxifene 4'-glucuronide formation is mediated mostly by UGT1A10 and UGT1A8. Raloxifene 4'-glucuronide binds to estrogen receptor with an IC50 of 370 μM. . Raloxifene is a selective estrogen receptor modulator. Raloxifene activates TGFβ3 promoter as a full agonist at nanomolar concentrations, and inhibits the estrogen response element-containing vitellogenin promoter expression [3].
Cat. No.: HY-P2612
CAS No.: 199999-60-5
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Cat. No.: HY-P991084
Target:
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Cat. No.: HY-135581
CAS No.: 174264-50-7
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Raloxifene 6-glucuronide is a primary metabolite of Raloxifene. Raloxifene 6-glucuronide is mediated mostly by UGT1A1 and UGT1A8. Raloxifene 6-glucuronide binds to estrogen receptor with an IC50 of 290 μM. Raloxifene is a selective and nonsteroidal estrogen receptor modulator. Raloxifene activates TGFβ3 promoter as a full agonist at nanomolar concentrations, and inhibits the estrogen response element-containing vitellogenin promoter expression [3].
Cat. No.: HY-135581S1
Cat. No.: HY-135582S1
Cat. No.: HY-135582S
CAS No.: 1279033-52-1
Cat. No.: HY-P992453
Synonyms: MTBT1466A; RG-6315
Target:
Research Areas:
Cat. No.: HY-P701080
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TGFB3; Transforming Growth Factor, Beta 3; Prev. ARVD1; Transforming Growth Factor Beta; Prev. ARVD; TGF-Beta3; Transforming Growth Factor Beta-3 Proprotein; LDS5; Prepro-Transforming Growth Factor Beta-3; RNHF; Arrhythmogenic Right Ventricular Dysplasia
Cat. No.: HY-P700786
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TGFB3; Transforming Growth Factor, Beta 3; Prev. ARVD1; Transforming Growth Factor Beta; Prev. ARVD; TGF-Beta3; Transforming Growth Factor Beta-3 Proprotein; LDS5; Prepro-Transforming Growth Factor Beta-3; RNHF; Arrhythmogenic Right Ventricular Dysplasia
Cat. No.: HY-P700890
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TGFB3; Transforming Growth Factor, Beta 3; Prev. ARVD1; Transforming Growth Factor Beta; Prev. ARVD; TGF-Beta3; Transforming Growth Factor Beta-3 Proprotein; LDS5; Prepro-Transforming Growth Factor Beta-3; RNHF; Arrhythmogenic Right Ventricular Dysplasia
Cat. No.: HY-P86472
Synonyms: Transforming growth factor beta-1 proprotein; Latency-associated peptide; LAP; Transforming growth factor beta-1; TGF-beta-1; Transforming growth factor beta-3 proprotein; Transforming growth factor beta-3; TGF-beta-3;
Cat. No.: HY-P87104
Synonyms: ARVD antibody; ARVD1 antibody; FLJ16571 antibody; LDS5 antibody; MGC105479 antibody; MGC118722 antibody; prepro-transforming growth factor beta-3 antibody; RNHF antibody; TGF beta 3 antibody; TGF beta3 antibody; ARVD antibody; ARVD1 antibody; FLJ16571 antibody; LDS5 antibody; MGC105479 antibody; MGC118722 antibody; prepro-transforming growth factor beta-3 antibody; RNHF antibody; TGF beta 3 antibody; TGF beta3 antibody; TGF-beta-3 antibody; TGFB 3 antibody; Tgfb3 antibody; TGFB3_HUMAN antibody; transforming growth factor beta 3 antibody; Transforming growth factor beta-3 antibody;
Cat. No.: HY-P78802
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: TGFB3; Transforming Growth Factor, Beta 3; Prev. ARVD1; Transforming Growth Factor Beta; Prev. ARVD; TGF-Beta3; Transforming Growth Factor Beta-3 Proprotein; LDS5; Prepro-Transforming Growth Factor Beta-3; RNHF; Arrhythmogenic Right Ventricular Dysplasia
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
