35 Results for "

Trophoblast

" in MedChemExpress (MCE) Product Catalog:
Products (35)

35 Results for "Trophoblast" in MCE Product Catalog:

9
9 Publications Verification
Cat. No.: HY-P99045
CAS No.: 1796566-95-4
Synonyms: HRS7; hRS7

Target:  

ADC Antibodies TROP2

Research Areas:  

Cancer

Sacituzumab is a humanized IgG1 monoclonal antibody targeting Trophoblast cell surface antigen 2 (TROP2). Sacituzumab demonstrates a lack of antitumor effects alone and does not inhibit the function of TROP-2 during tumor metastasis, binding to the linear epitopes of TROP-2 protein. Sacituzumab can be used for the synthesis of antibody-drug conjugates (ADC) drug Sacituzumab govitecan (HY-132254). Sacituzumab govitecan can be used in the field of triple-negative breast cancer .
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-P99843
CAS No.: 2267989-53-5

Target:  

TROP2 ADC Antibodies

Research Areas:  

Cancer

Datopotamab is a humanized anti trophoblast cell surface antigen 2 (TROP2) antibody. Datopotamab can generate antibody drug conjugates (ADC) (HY-141598) with DNA topoisomerase I inhibitor Deruxtecan (HY-13631E). Datopotamab can be used in the study of triple negative breast cancer and non-small cell lung cancer .
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-17587
CAS No.: 36861-47-9
Synonyms: 4-MBC; Enzacamene
Target:  

Apoptosis PI3K Akt ERK

Research Areas:  

Metabolic Disease

4-Methylbenzylidene camphor (4-MBC) is an endocrine disrupter that produces estrogen-like effects. 4-Methylbenzylidene camphor decreases the proliferation of human trophoblast cells and induces apoptosis. 4-Methylbenzylidene camphor activates PI3K/AKT and ERK1/2 signaling pathways and elevates intracellular ROS production. 4-Methylbenzylidene camphor is a ultraviolet (UV) filter and may hamper normal placental formation during early pregnancy .
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-P71798
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Interferon tau-1; IFN-tau-1; Antiluteolysin; Trophoblast antiluteolytic protein; Trophoblast protein 1; TP-1; Trophoblastin; IFNT1
Species:  
Bovine
Source:  
P. pastoris
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-P81196
Synonyms: 3BHS1_HUMAN; 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1; beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type I; 3-beta-HSD I; 3-beta-hydroxy-5-ene steroid dehydrogenase 1; 3-beta-hydroxy-Delta(5)-steroid dehydrogenase 1; EC:1.1.1.145; 3-beta-hydroxysteroid 3-dehydrogenase 1; EC:1.1.1.270; Delta-5-3-ketosteroid isomerase; Dihydrotestosterone oxidoreductase. EC:1.1.1.210; Steroid Delta-isomerase 1; EC:5.3.3.1; Trophoblast antigen FDO161G; 3BH; HSDB3A;

Host:  

Rabbit

Application:  

WB, ICC/IF

Reactivity:  

Human

loading...
    loading...
Cat. No.: HY-P99045A
CAS No.: 1796566-95-4

Target:  

ADC Antibodies TROP2

Research Areas:  

Cancer

Sacituzumab (powder) is a humanized IgG1 monoclonal antibody targeting Trophoblast cell surface antigen 2 (TROP2). Sacituzumab (powder) demonstrates a lack of antitumor effects alone and does not inhibit the function of TROP-2 during tumor metastasis, binding to the linear epitopes of TROP-2 protein. Sacituzumab (powder) can be used for the synthesis of antibody-drug conjugates (ADC) drug Sacituzumab govitecan (HY-132254). Sacituzumab govitecan can be used in the field of triple-negative breast cancer .
loading...
    loading...
Cat. No.: HY-B0316
CAS No.: 70356-09-1
Avobenzone, a dibenzoylmethane compound, is one of the most widely used filters in sunscreens for skin photoprotection in the UVA band. Avobenzone is an endocrine disruptor that directly binds to estrogen receptor β and acts as an estrogen agonist .
loading...
    loading...
Cat. No.: HY-P5523A
iE-DAP dihydrochloride is a Nod1 agonist. iE-DAP dihydrochloride activates NOD1, which in turn activates the NF-κB signaling pathway and MLCK signaling pathway, inducing cellular inflammatory responses and tight junction disruption. iE-DAP dihydrochloride downregulates the expression of ZO-1 and Occludin genes. iE-DAP dihydrochloride increases the secretion of IL-6, GRO-α, MCP-1, IL-8 and MIP-1β in term human trophoblast cell cultures. iE-DAP dihydrochloride triggers preterm birth in pregnant mice, reduces fetal body weight, and induces fetal inflammation. iE-DAP dihydrochloride can be used in studies related to mastitis and preterm birth .
loading...
    loading...
Cat. No.: HY-B0316R
CAS No.: 70356-09-1
Research Areas:  

Others

Avobenzone (Standard) is the analytical standard of Avobenzone. This product is intended for research and analytical applications. Avobenzone, a dibenzoylmethane compound, is one of the most widely used filters in sunscreens for skin photoprotection in the UVA band. Avobenzone is an endocrine disruptor that directly binds to estrogen receptor β and acts as an estrogen agonist .
loading...
    loading...
Cat. No.: HY-P11101
CAS No.: 2294870-89-4
Research Areas:  

Others

plCSA-BP is a Placental CSA-binding peptide. plCSA-BP binds specifically to trophoblasts and not to other cell types in the placenta or to CSA-expressing cells in other tissues. plCSA-BP can guide nanoparticles for the targeted delivery of payloads (such as Indocyanine green (ICG) (HY-D0711) and Methotrexate (MTX) (HY-14519)) to the placenta, promising for placenta-specific drug delivery .
loading...
    loading...
Cat. No.: HY-P5523
CAS No.: 592520-07-5
iE-DAP is a Nod1 agonist. iE-DAP activates NOD1, which in turn activates the NF-κB signaling pathway and MLCK signaling pathway, inducing cellular inflammatory responses and tight junction disruption. iE-DAP downregulates the expression of ZO-1 and Occludin genes. iE-DAP increases the secretion of IL-6, GRO-α, MCP-1, IL-8 and MIP-1β in term human trophoblast cell cultures. iE-DAP triggers preterm birth in pregnant mice, reduces fetal body weight, and induces fetal inflammation. iE-DAP is applicable to research related to mastitis and preterm birth .
loading...
    loading...
Cat. No.: HY-W019780
CAS No.: 75-27-4
Synonyms: Dichlorobromomethane
Research Areas:  

Metabolic Disease Cancer

Bromodichloromethane (Dichlorobromomethane) is a type of trihalomethane, commonly found in chlorinated drinking water for disinfection, and is a disinfection by-product. The bromination of bromodichloromethane can cause the formation of mutagenic intermediates through the transformation mediated by glutathione S-transferase (GST). Bromodichloromethane inhibits the differentiation of human placental trophoblast cells and reduces the secretion of chorionic gonadotropin (CG). Bromodichloromethane has potential reproductive toxicity and carcinogenicity .
loading...
    loading...
Cat. No.: HY-17587R
CAS No.: 36861-47-9
Synonyms: 4-MBC (Standard); Enzacamene (Standard)
Research Areas:  

Metabolic Disease

4-Methylbenzylidene camphor (Standard) is the analytical standard of 4-Methylbenzylidene camphor. This product is intended for research and analytical applications. 4-Methylbenzylidene camphor (4-MBC) is an endocrine disrupter that produces estrogen-like effects. 4-Methylbenzylidene camphor decreases the proliferation of human trophoblast cells and induces apoptosis. 4-Methylbenzylidene camphor activates PI3K/AKT and ERK1/2 signaling pathways and elevates intracellular ROS production. 4-Methylbenzylidene camphor is a ultraviolet (UV) filter and may hamper normal placental formation during early pregnancy .
loading...
    loading...
Cat. No.: HY-P705558
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Interferon tau-1; IFN-tau-1; Antiluteolysin; Trophoblast antiluteolytic protein; Trophoblast protein 1; TP-1; Trophoblastin; IFNT1; OTP
Species:  
Sheep
Source:  
P. pastoris
loading...
    loading...
Cat. No.: HY-P99843A

Target:  

TROP2 ADC Antibodies

Research Areas:  

Cancer

Datopotamab (powder) is a humanized anti trophoblast cell surface antigen 2 (TROP2) antibody. Datopotamab (powder) can generate antibody drug conjugates (ADC) (HY-141598) with DNA topoisomerase I inhibitor Deruxtecan (HY-13631E). Datopotamab (powder) can be used in the study of triple negative breast cancer and non-small cell lung cancer .
loading...
    loading...
Cat. No.: HY-P87948
Synonyms: 5T4, TPBG, Trophoblast glycoprotein, 5T4 oncofetal antigen, 5T4 oncofetal Trophoblast glycoprotein, M6P1, Wnt-activated inhibitory factor 1, 5T4 oncoTrophoblast glycoprotein, WAIF1

Host:  

Rabbit

Application:  

WB, IHC-P, IHC-F

Reactivity:  

Human

loading...
    loading...
Cat. No.: HY-P70071
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TPBG; 5T4 Oncofetal Antigen; Trophoblast Glycoprotein; 5T4-AG; 5T4; WAIF1; 5T4 Oncofetal Trophoblast Glycoprotein; M6P1; Wnt-Activated Inhibitory Factor 1; 5T4AG; 5T4 OncoTrophoblast Glycoprotein
Species:  
Cynomolgus
Source:  
HEK293
loading...
    loading...
Cat. No.: HY-P70121
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TPBG; 5T4 Oncofetal Antigen; Trophoblast Glycoprotein; 5T4-AG; 5T4; WAIF1; 5T4 Oncofetal Trophoblast Glycoprotein; M6P1; Wnt-Activated Inhibitory Factor 1; 5T4AG; 5T4 OncoTrophoblast Glycoprotein
Species:  
Mouse
Source:  
HEK293
loading...
    loading...
Cat. No.: HY-P70512
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TPBG; 5T4 Oncofetal Antigen; Trophoblast Glycoprotein; 5T4-AG; 5T4; WAIF1; 5T4 Oncofetal Trophoblast Glycoprotein; M6P1; Wnt-Activated Inhibitory Factor 1; 5T4AG; 5T4 OncoTrophoblast Glycoprotein
Species:  
Human
Source:  
HEK293
loading...
    loading...
Cat. No.: HY-P72421
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TPBG; 5T4 Oncofetal Antigen; Trophoblast Glycoprotein; 5T4-AG; 5T4; WAIF1; 5T4 Oncofetal Trophoblast Glycoprotein; M6P1; Wnt-Activated Inhibitory Factor 1; 5T4AG; 5T4 OncoTrophoblast Glycoprotein
Species:  
Human
Source:  
HEK293
loading...
    loading...