Bromodichloromethane
Bromodichloromethane (Dichlorobromomethane) is a type of trihalomethane, commonly found in chlorinated drinking water for disinfection, and is a disinfection by-product. The bromination of bromodichloromethane can cause the formation of mutagenic intermediates through the transformation mediated by glutathione S-transferase (GST). Bromodichloromethane inhibits the differentiation of human placental trophoblast cells and reduces the secretion of chorionic gonadotropin (CG). Bromodichloromethane has potential reproductive toxicity and carcinogenicity.
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- CAS No.: 75-27-4
- Formula: CHBrCl2
- Molecular Weight:163.83
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Chemical Information
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CAS No. 75-27-4
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Molecular Weight 163.83
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Formula CHBrCl2
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SMILES
ClC(Br)Cl
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Synonyms
Dichlorobromomethane
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Pegram RA, et al. Glutathione S-transferase-mediated mutagenicity of trihalomethanes in Salmonella typhimurium: contrasting results with bromodichloromethane off chloroform. Toxicol Appl Pharmacol. 1997 May;144(1):183-8. [Content Brief]
[2]. Chen J, et al. Bromodichloromethane inhibits human placental trophoblast differentiation. Toxicol Sci. 2004 Mar;78(1):166-74. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Bromodichloromethane Related Classifications
HY-W019780 Related Classifications
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