5T4 Antibody (YA1097)
(Synonyms: TPBG,5T4,5T4 oncofetal antigen,5T4 oncofetal trophoblast glycoprotein (5T4 oncotrophoblast glycoprotein),M6P1,Wnt-activated inhibitory factor 1 (WAIF1))5T4 Antibody (YA1097) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to 5T4.
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Host:
Rabbit
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Isotype:
IgG
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Application:
IHC-P
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Reactivity :
Human
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Formulation:
Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.185.
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Conjugation:
Non-conjugated
Applications
| Application |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
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|---|---|
| Dilution Ratio | 1:100-1:200 |
Product Details
5T4 Antibody (YA1097) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to 5T4.
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Host Rabbit
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Clonality Recombinant, Monoclonal
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Species ReactivityHuman
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Observed Molecular WeightObserved band size: 80 kDaNote: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 46 kDa
A synthesized peptide derived from human 5T4
Endogenous
Affinity Purified
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Liquid
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Formulation
Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.185.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
5T4 may function as an inhibitor of Wnt/beta-catenin signaling by indirectly interacting with LRP6 and blocking Wnt3a-dependent LRP6 internalization
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Subcellular Localization
Cell membrane; Single-pass type I membrane protein
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Expression
Tissue_specificity:Expressed by all types of trophoblasts as early as 9 weeks of development. Specific for trophoblastic cells except for amniotic epithelium. In adult tissues, the expression is limited to a few epithelial cell types but is found on a variety of carcinoma -
SwissProt ID
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Synonyms
TPBG,5T4,5T4 oncofetal antigen,5T4 oncofetal trophoblast glycoprotein (5T4 oncotrophoblast glycoprotein),M6P1,Wnt-activated inhibitory factor 1 (WAIF1)
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Research Field
Stem Cells
Documentation