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Nitro blue tetrazolium chloride (NBT) is a substrate for dehydrogenases; is used with the alkaline phosphatase substrate 5-Bromo-4-Chloro-3-Indolyl Phosphate (BCIP) in western blotting and immunohistological staining procedures .
Ponceau S (Acid Red 112) is a non-specific protein dye commonly used as a stain for Western blot. Ponceau S is used in an acidic aqueous solution that is compatible with antibody-antigen binding and dyes the proteins on the membrane red .
AMPSO is an alkaline transfer buffer that can be used to transfer strongly basic proteins from gels into nitrocellulose without reducing the transfer efficiency of other proteins. AMPSO can be used for Western Blot analysis, PCR amplification and many other applications .
PF-07202954 is a weakly basic DGAT2 inhibitor with an IC50 of 10 nM for human DGAT2. PF-07202954 lowers liver triglyceride content in a Western-diet-fed rat model .
5(6)-FITC (Fluorescein 5(6)-isothiocyanate) is an amine-reactive derivative of fluorescein dye that has wide-ranging applications as a label for antibodies and other probes, for use in fluorescence microscopy, flow cytometry and immunofluorescence-based assays such as Western blotting and ELISA.
Heme Oxygenase-2-IN-1 (Compound 9) is a potent, selective heme oxygenase-2 (HO-2) inhibitor with IC50 values of 0.9 μM and 14.9 μM against HO-2 and HO-1, respectively .
Both Ponceau S and Ponceau BS are synthetic dyes commonly used in biological research. They are commonly used as protein stains to visualize proteins in western blots and other protein detection analyses. Ponceau S is a red dye, while Ponceau BS is a blue shade of the same dye. Both dyes bind to positively charged amino acid residues in proteins for easy visualization. However, Ponceau S is more commonly used due to its higher sensitivity.
PTZ-343 is a potent enhancer of Luminol (HY-15922). PTZ-343 greatly increases the light output of the peroxidase-catalyzed luminol chemiluminescent oxidation reaction (>80%) .
AG6033 is a potential novel CRBN modulator. AG6033 suppresses various tumor cells by modulating the interactions between CRBN and various antitumor target proteins. AG6033 can cause GSPT1 and IKZF1 degradation. AG6033 induces CRBN-dependent cytotoxic effect .
Photobiotin (acetate)It is a biological probe used to study biochemical processes such as protein interactions and enzymatic reactions. It is a molecule containing a photosensitive group, which can be combined with specific target molecules (such as proteins, nucleic acids, etc.) through photochemical cross-linking technology, so as to realize the labeling and detection of these molecules. During the photosensitive crosslinking process, Photobiotin (acetate)Can participate in the formation of covalent bonds and form stable compounds. In addition, the compound also has high biocompatibility and biological activity, so it is widely used in the field of biomedical research, such as enzymatic research, proteomics, western blotting and other aspects. Photobiotin (acetate) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
Caerin 1.1 TFA is a host defense peptide isolated from the glandular secretions of the Australian tree frog Litoria. Caerin 1.1 TFA inhibits HeLa cell proliferation and mediates apoptosis. Caerin 1.1 TFA may enhance adaptive T cell immune responses .
Chinese herbal therapy is an important part of Traditional Chinese Medicine (TCM). It has been used for centuries in China, where herbs are considered fundamental therapy for many acute and chronic conditions. Many studies indicated TCM exerted an overall regulatory effect via multi-component and multi-target network. Active components from Traditional Chinese Medicine possess many medicinal properties such as antioxidant, anti-cancer, and anti-bacterial effects, which makes it an important source of new drugs. Nearly 200 modern medicines have been developed either directly or indirectly from the plants used as medicines in China. For example, artemisinin, used in multidrug resistant malaria, was first isolated from the Chinese herb Artemisia annua L. Today, scientists continue to identify compounds in Chinese herbal remedies that may be useful in the development of new therapeutic agents applicable in Western medicine.
MCE designs a unique collection of 2845 active compounds of Chinese Herbal Medicines. MCE Traditional Chinese Medicine Active Compound Library is a useful tool for discovery new drugs from TCM.
Nitro blue tetrazolium chloride (NBT) is a substrate for dehydrogenases; is used with the alkaline phosphatase substrate 5-Bromo-4-Chloro-3-Indolyl Phosphate (BCIP) in western blotting and immunohistological staining procedures .
Ponceau S (Acid Red 112) is a non-specific protein dye commonly used as a stain for Western blot. Ponceau S is used in an acidic aqueous solution that is compatible with antibody-antigen binding and dyes the proteins on the membrane red .
5(6)-FITC (Fluorescein 5(6)-isothiocyanate) is an amine-reactive derivative of fluorescein dye that has wide-ranging applications as a label for antibodies and other probes, for use in fluorescence microscopy, flow cytometry and immunofluorescence-based assays such as Western blotting and ELISA.
Both Ponceau S and Ponceau BS are synthetic dyes commonly used in biological research. They are commonly used as protein stains to visualize proteins in western blots and other protein detection analyses. Ponceau S is a red dye, while Ponceau BS is a blue shade of the same dye. Both dyes bind to positively charged amino acid residues in proteins for easy visualization. However, Ponceau S is more commonly used due to its higher sensitivity.
AMPSO is an alkaline transfer buffer that can be used to transfer strongly basic proteins from gels into nitrocellulose without reducing the transfer efficiency of other proteins. AMPSO can be used for Western Blot analysis, PCR amplification and many other applications .
Photobiotin (acetate)It is a biological probe used to study biochemical processes such as protein interactions and enzymatic reactions. It is a molecule containing a photosensitive group, which can be combined with specific target molecules (such as proteins, nucleic acids, etc.) through photochemical cross-linking technology, so as to realize the labeling and detection of these molecules. During the photosensitive crosslinking process, Photobiotin (acetate)Can participate in the formation of covalent bonds and form stable compounds. In addition, the compound also has high biocompatibility and biological activity, so it is widely used in the field of biomedical research, such as enzymatic research, proteomics, western blotting and other aspects. Photobiotin (acetate) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
Abl protein tyrosine kinase substrate is a biological active peptide. (Abltide is a peptide substrate for Abl Kinase (Abl protein tyrosine kinase), a partner in the gag-Abl fusion protein of the Abelson murine leukemia virus. Used in Western blot and kinase assay.)
Caerin 1.1 TFA is a host defense peptide isolated from the glandular secretions of the Australian tree frog Litoria. Caerin 1.1 TFA inhibits HeLa cell proliferation and mediates apoptosis. Caerin 1.1 TFA may enhance adaptive T cell immune responses .
MCE Tris-Glycine-SDS Powder (1 L of 1×) consists of Tris, Glycine and SDS, and is widely used as an electrophoresis buffer for SDS-PAGE and Western Blot.
MCE Ultra High Sensitivity ECL Kit is an ultra-sensitive, luminol-based enhanced chemiluminescent substrate for detecting horseradish peroxidase (HRP) labeled antibodies on western blots.
MCE PBS-T Powder (1 L of 1×) consists of NaCl, KCl, Phosphate and Tween 20, and is widely used in ELISA and Western Blot, and can also be used for antibody dilution and preparation of blocking solution.
MCE Rapid Blocking Buffer (TBS-T) Powder (100 mL of 1×) mainly consists of fish gelatin protein, and is widely used for the antibody blocking step in Western Blot or ELISA within 15 minutes.
The hemagglutinin HA1 protein is essential for attachment of virions to host cells by binding to sialic acid-containing receptors, inducing virion internalization via clathrin-dependent or clathrin- and caveolin-independent pathways. As a class I viral fusion protein, HA1 determines host range restriction and virulence, mediating fusion between the virion membrane and the endosomal membrane. Hemagglutinin/HA Protein, H15N2 (ABB90704, sf9, His) is the recombinant Virus-derived Hemagglutinin/HA protein, expressed by Sf9 insect cells , with C-His labeled tag. The total length of Hemagglutinin/HA Protein, H15N2 (ABB90704, sf9, His) is 534 a.a., with molecular weight of ~64.5 kDa.
The hemagglutinin HA1 protein is essential for attachment of virions to host cells by binding to sialic acid-containing receptors, inducing virion internalization via clathrin-dependent or clathrin- and caveolin-independent pathways. As a class I viral fusion protein, HA1 determines host range restriction and virulence, mediating fusion between the virion membrane and the endosomal membrane. HA1/Hemagglutinin Protein, H15N2 (ABB90704, HEK293, His) is the recombinant Virus-derived HA1/Hemagglutinin protein, expressed by HEK293 , with C-His labeled tag. The total length of HA1/Hemagglutinin Protein, H15N2 (ABB90704, HEK293, His) is 349 a.a., with molecular weight of ~51.6 kDa.
Photobiotin (acetate)It is a biological probe used to study biochemical processes such as protein interactions and enzymatic reactions. It is a molecule containing a photosensitive group, which can be combined with specific target molecules (such as proteins, nucleic acids, etc.) through photochemical cross-linking technology, so as to realize the labeling and detection of these molecules. During the photosensitive crosslinking process, Photobiotin (acetate)Can participate in the formation of covalent bonds and form stable compounds. In addition, the compound also has high biocompatibility and biological activity, so it is widely used in the field of biomedical research, such as enzymatic research, proteomics, western blotting and other aspects. Photobiotin (acetate) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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