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ailanthus+altissima

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Bacterial (1) Drug Derivative (1) MDM-2/p53 (1) Parasite (2) Sirtuin (1)
By Research Areas:	Cancer (2) Infection (3) Inflammation/Immunology (1) Neurological Disease (1)

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Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N1203

(5α)-Stigmastane-3,6-dione	Bacterial	Infection Inflammation/Immunology
(5α)-Stigmastane-3,6-dione is a naturally occurring sterol that could be isolated from fruits of Ailanthus altissima Swingle. Antimicrobial Activity. .

HY-N2926

β-Carboline-1-propionic acid	Parasite	Infection
β-Carboline-1-propionic acid is a alkaloid which can be extracted from Ailanthus altissima. β-Carboline-1-propionic acid can be used as an antileishmanial agent .

HY-N8612

4,9-Dimethoxycanthin-6-one	Others	Others
4,9-Dimethoxycanthin-6-one is a Alkaloids product that can be isolated from the barks of Ailanthus altissima .

HY-N8620

9-Methoxycanthin-6-one-N-oxide	Others	Others
9-Methoxycanthin-6-one-N-oxide is a Alkaloids product that can be isolated from the barks of Ailanthus altissima .

HY-N9194

5-Methoxycanthin-6-one	Parasite	Infection
5-Methoxycanthin-6-one is an orally active inhibitor of Leishmania strains. 5-Methoxycanthin-6-one shows cytotoxicity with an IC₅₀ of 5.44 μg/mL against Ailanthus altissima cells .

HY-N12964

4-Hydroxycanthin-6-one	Others	Others
4-Hydroxycanthin-6-one is a novel quinoline alkaloid isolated from the stem bark of the tree Ailanthus altissima. Five other known compounds were also found in the study. The structures of the new compounds were determined by interpretation of physical and spectroscopic data, and their absolute configurations were determined by electronic circular dichroism spectroscopy and quantum chemical calculations. These compounds showed significant inhibitory activity against lipopolysaccharide (LPS)-induced nitric oxide (NO) production in RAW 264.7 cells, showing potential anti-inflammatory properties .

HY-N8710

Shinjulactone L	Others	Others
Shinjulactone L is a Diterpenoids product that can be isolated from the barks of Ailanthus altissima .

HY-N18017

Shinjuglycoside C	Drug Derivative	Others
Shinjuglycoside C (Compound 3) is a quassinoid glycoside that can be isolated from the seeds of Ailanthus altissima. Shinjuglycoside C exhibits a bitter taste .

HY-N17951

Amarolide 11-acetate	Others	Others
Amarolide 11-acetate is a quassinoid, can be found in the barks of Ailanthus altissima.Amarolide 11-acetate exhibits nearly inactive cytotoxicity against human hepatoma cells .

HY-N18379

Altissimacoumarin L	Others	Cancer
Altissimacoumarin L is a terpenylated coumarin. Altissimacoumarin L can be isolated from the root bark of Ailanthus altissima (Mill.) Swingle. Altissimacoumarin L shows no significant cytotoxic activity against hepatoma cells .

HY-N18378

Altissimacoumarin K	Others	Cancer
Altissimacoumarin K is a terpenylated coumarin. Altissimacoumarin K can be isolated from the root bark of Ailanthus altissima (Mill.) Swingle. Altissimacoumarin K exhibits no significant cytotoxic effect against hepatoma cells .

HY-N18386

Altissimacoumarin F	Sirtuin MDM-2/p53	Neurological Disease
Altissimacoumarin F (Compound 4) is a terpenylated coumarin. Altissimacoumarin F can be isolated from the stem bark of Ailanthus altissima. Altissimacoumarin F enhances SIRT1 activity, decreases p53 transcriptional activity. Altissimacoumarin F can be used for the research of age-related disorders .

(5α)-Stigmastane-3,6-dione	Simaroubaceae Ailanthus altissima (Mill.) Swingle Classification of Application Fields Plants Disease Research Fields Inflammation/Immunology Steroids Source Classification	Bacterial
(5α)-Stigmastane-3,6-dione is a naturally occurring sterol that could be isolated from fruits of Ailanthus altissima Swingle. Antimicrobial Activity. .

β-Carboline-1-propionic acid	Alkaloids Simaroubaceae Ailanthus altissima (Mill.) Swingle Pyrrole Alkaloids Plants Source Classification	Parasite
β-Carboline-1-propionic acid is a alkaloid which can be extracted from Ailanthus altissima. β-Carboline-1-propionic acid can be used as an antileishmanial agent .

4,9-Dimethoxycanthin-6-one	Alkaloids Simaroubaceae Ailanthus altissima (Mill.) Swingle Other Alkaloids Plants Source Classification	Others
4,9-Dimethoxycanthin-6-one is a Alkaloids product that can be isolated from the barks of Ailanthus altissima .

9-Methoxycanthin-6-one-N-oxide	Alkaloids Simaroubaceae Ailanthus altissima (Mill.) Swingle Plants Indole Alkaloids Source Classification	Others
9-Methoxycanthin-6-one-N-oxide is a Alkaloids product that can be isolated from the barks of Ailanthus altissima .

5-Methoxycanthin-6-one	Infection Alkaloids Classification of Application Fields Rutaceae Pyridine Alkaloids Zanthoxylum chiloperone var. angustifolium Plants Disease Research Fields Indole Alkaloids Source Classification	Parasite
5-Methoxycanthin-6-one is an orally active inhibitor of Leishmania strains. 5-Methoxycanthin-6-one shows cytotoxicity with an IC₅₀ of 5.44 μg/mL against Ailanthus altissima cells .

4-Hydroxycanthin-6-one	Alkaloids Simaroubaceae Ailanthus altissima (Mill.) Swingle Quinoline Alkaloids Plants Source Classification	Others
4-Hydroxycanthin-6-one is a novel quinoline alkaloid isolated from the stem bark of the tree Ailanthus altissima. Five other known compounds were also found in the study. The structures of the new compounds were determined by interpretation of physical and spectroscopic data, and their absolute configurations were determined by electronic circular dichroism spectroscopy and quantum chemical calculations. These compounds showed significant inhibitory activity against lipopolysaccharide (LPS)-induced nitric oxide (NO) production in RAW 264.7 cells, showing potential anti-inflammatory properties .

Shinjulactone L	Simaroubaceae Ailanthus altissima (Mill.) Swingle Terpenoids Diterpenoids Plants Source Classification	Others
Shinjulactone L is a Diterpenoids product that can be isolated from the barks of Ailanthus altissima .

Shinjuglycoside C	Triterpenes Structural Classification Simaroubaceae Ailanthus altissima (Mill.) Swingle Terpenoids Plants Source Classification	Drug Derivative
Shinjuglycoside C (Compound 3) is a quassinoid glycoside that can be isolated from the seeds of Ailanthus altissima. Shinjuglycoside C exhibits a bitter taste .

Amarolide 11-acetate	Structural Classification Simaroubaceae Ailanthus altissima (Mill.) Swingle Terpenoids Salvia hypargeia Fisch. & C.A.Mey. Plants Compositae Pentacyclic Triterpenoids Source Classification	Others
Amarolide 11-acetate is a quassinoid, can be found in the barks of Ailanthus altissima.Amarolide 11-acetate exhibits nearly inactive cytotoxicity against human hepatoma cells .

Altissimacoumarin L	Structural Classification Simaroubaceae Ailanthus altissima (Mill.) Swingle Coumarins Phenylpropanoids Plants Source Classification	Others
Altissimacoumarin L is a terpenylated coumarin. Altissimacoumarin L can be isolated from the root bark of Ailanthus altissima (Mill.) Swingle. Altissimacoumarin L shows no significant cytotoxic activity against hepatoma cells .

Altissimacoumarin K	Structural Classification Simaroubaceae Ailanthus altissima (Mill.) Swingle Coumarins Phenylpropanoids Plants Source Classification	Others
Altissimacoumarin K is a terpenylated coumarin. Altissimacoumarin K can be isolated from the root bark of Ailanthus altissima (Mill.) Swingle. Altissimacoumarin K exhibits no significant cytotoxic effect against hepatoma cells .

Altissimacoumarin F	Structural Classification Simaroubaceae Ailanthus altissima (Mill.) Swingle Coumarins Phenylpropanoids Plants Source Classification	Sirtuin MDM-2/p53
Altissimacoumarin F (Compound 4) is a terpenylated coumarin. Altissimacoumarin F can be isolated from the stem bark of Ailanthus altissima. Altissimacoumarin F enhances SIRT1 activity, decreases p53 transcriptional activity. Altissimacoumarin F can be used for the research of age-related disorders .

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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ailanthus+altissima

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