Altissimacoumarin F
Altissimacoumarin F (Compound 4) is a terpenylated coumarin. Altissimacoumarin F can be isolated from the stem bark of Ailanthus altissima. Altissimacoumarin F enhances SIRT1 activity, decreases p53 transcriptional activity. Altissimacoumarin F can be used for the research of age-related disorders.
For research use only. We do not sell to patients.
- CAS No.: 1384897-64-6
- Formula: C21H26O7
- Molecular Weight:390.43
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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SIRT1 |
Altissimacoumarin F (10 μM; 10 min) enhances in vitro SIRT1 deacetylation activity[1].
Altissimacoumarin F (5-20 μM; 12 h post-transfection treatment) dose-dependently decreases p53 transcriptional activity in SIRT1-expressing HEK293 cells[1].
Altissimacoumarin F (20 μM; 12 h) increases the intracellular NAD-to-NADH ratio in HEK293 cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1384897-64-6
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Molecular Weight 390.43
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Formula C21H26O7
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SMILES
O=C1OC2=C(OC)C(OC[C@H](O)[C@@H](C)[C@@H](O3)[C@@H]3/C=C(C)/C)=C(OC)C=C2C=C1
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Altissimacoumarin F Related Classifications
HY-N18386 Related Classifications
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