9-Methoxycanthin-6-one-N-oxide
9-Methoxycanthin-6-one-N-oxide is a Alkaloids product that can be isolated from the barks of Ailanthus altissima.
For research use only. We do not sell to patients.
- CAS No.: 137739-74-3
- Formula: C15H10N2O3
- Molecular Weight:266.25
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| A549 | ED50 |
18.5 μg/mL
Compound: 9-methoxycanthin-6-one 3N-oxide
|
Cytotoxicity against human A549 cells by SRB assay
Cytotoxicity against human A549 cells by SRB assay
|
[PMID: 14575431] |
| Breast carcinoma cell | IC50 |
3.8 μg/mL
Compound: 30
|
Cytotoxicity against human Breast cancer cell
Cytotoxicity against human Breast cancer cell
|
[PMID: 34332400] |
| Cancer cell lines | ED50 |
5.2 μg/mL
Compound: 2
|
Cytotoxicity against human lung cancer cells
Cytotoxicity against human lung cancer cells
|
[PMID: 1800638] |
| Cancer cell lines | ED50 |
6 μg/mL
Compound: 2
|
Cytotoxicity against human breast cancer cells
Cytotoxicity against human breast cancer cells
|
[PMID: 1800638] |
| Cancer cell lines | ED50 |
8.1 μg/mL
Compound: 2
|
Cytotoxicity against human colon cancer cells
Cytotoxicity against human colon cancer cells
|
[PMID: 1800638] |
| Colon cancer cell line | IC50 |
3.8 μg/mL
Compound: 30
|
Cytotoxicity against human Colon cancer cell line
Cytotoxicity against human Colon cancer cell line
|
[PMID: 34332400] |
| Fibrosarcoma cell line | IC50 |
3.8 μg/mL
Compound: 30
|
Cytotoxicity against human Fibrosarcoma cell line
Cytotoxicity against human Fibrosarcoma cell line
|
[PMID: 34332400] |
| KB | ED50 |
3.8 μg/mL
Compound: 2
|
Cytotoxicity against human KB cells
Cytotoxicity against human KB cells
|
[PMID: 1800638] |
| KB | IC50 |
3.8 μg/mL
Compound: 30
|
Cytotoxicity against human Vincristine-resistant KB cells
Cytotoxicity against human Vincristine-resistant KB cells
|
[PMID: 34332400] |
| KB-V1 | ED50 |
>20 μg/mL
Compound: 2
|
Cytotoxicity against human KBV1 cells
Cytotoxicity against human KBV1 cells
|
[PMID: 1800638] |
| Lung cancer cell line | IC50 |
3.8 μg/mL
Compound: 30
|
Cytotoxicity against human Lung cancer cell line
Cytotoxicity against human Lung cancer cell line
|
[PMID: 34332400] |
| MCF7 | ED50 |
18.9 μg/mL
Compound: 9-methoxycanthin-6-one 3N-oxide
|
Cytotoxicity against human MCF7 cells by SRB assay
Cytotoxicity against human MCF7 cells by SRB assay
|
[PMID: 14575431] |
| Melanoma cell | ED50 |
6.5 μg/mL
Compound: 2
|
Cytotoxicity against human melanoma cells
Cytotoxicity against human melanoma cells
|
[PMID: 1800638] |
| Melanoma cell line | IC50 |
3.8 μg/mL
Compound: 30
|
Cytotoxicity against human Melanoma cell line
Cytotoxicity against human Melanoma cell line
|
[PMID: 34332400] |
| P388 | ED50 |
11.7 μg/mL
Compound: 2
|
Cytotoxicity against mouse P388 cells
Cytotoxicity against mouse P388 cells
|
[PMID: 1800638] |
Chemical Information
-
CAS No. 137739-74-3
-
Molecular Weight 266.25
-
Formula C15H10N2O3
-
SMILES
O=C1N2C3=C(C4=C2C=C(OC)C=C4)C=C[N+]([O-])=C3C=C1
-
Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)