1. Natural Products
  2. Plants Alkaloids
  3. Simaroubaceae Indole Alkaloids
  4. Ailanthus altissima (Mill.) Swingle
  5. 9-Methoxycanthin-6-one-N-oxide

9-Methoxycanthin-6-one-N-oxide is a Alkaloids product that can be isolated from the barks of Ailanthus altissima.

For research use only. We do not sell to patients.

9-Methoxycanthin-6-one-N-oxide

9-Methoxycanthin-6-one-N-oxide Chemical Structure

CAS No. : 137739-74-3

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Description

9-Methoxycanthin-6-one-N-oxide is a Alkaloids product that can be isolated from the barks of Ailanthus altissima[1].

Cellular Effect
Cell Line Type Value Description References
A549 ED50
18.5 μg/mL
Compound: 9-methoxycanthin-6-one 3N-oxide
Cytotoxicity against human A549 cells by SRB assay
Cytotoxicity against human A549 cells by SRB assay
[PMID: 14575431]
Breast carcinoma cell IC50
3.8 μg/mL
Compound: 30
Cytotoxicity against human Breast cancer cell
Cytotoxicity against human Breast cancer cell
[PMID: 34332400]
Cancer cell lines ED50
5.2 μg/mL
Compound: 2
Cytotoxicity against human lung cancer cells
Cytotoxicity against human lung cancer cells
[PMID: 1800638]
Cancer cell lines ED50
6 μg/mL
Compound: 2
Cytotoxicity against human breast cancer cells
Cytotoxicity against human breast cancer cells
[PMID: 1800638]
Cancer cell lines ED50
8.1 μg/mL
Compound: 2
Cytotoxicity against human colon cancer cells
Cytotoxicity against human colon cancer cells
[PMID: 1800638]
Colon cancer cell line IC50
3.8 μg/mL
Compound: 30
Cytotoxicity against human Colon cancer cell line
Cytotoxicity against human Colon cancer cell line
[PMID: 34332400]
Fibrosarcoma cell line IC50
3.8 μg/mL
Compound: 30
Cytotoxicity against human Fibrosarcoma cell line
Cytotoxicity against human Fibrosarcoma cell line
[PMID: 34332400]
KB ED50
3.8 μg/mL
Compound: 2
Cytotoxicity against human KB cells
Cytotoxicity against human KB cells
[PMID: 1800638]
KB IC50
3.8 μg/mL
Compound: 30
Cytotoxicity against human Vincristine-resistant KB cells
Cytotoxicity against human Vincristine-resistant KB cells
[PMID: 34332400]
KB-V1 ED50
> 20 μg/mL
Compound: 2
Cytotoxicity against human KBV1 cells
Cytotoxicity against human KBV1 cells
[PMID: 1800638]
Lung cancer cell line IC50
3.8 μg/mL
Compound: 30
Cytotoxicity against human Lung cancer cell line
Cytotoxicity against human Lung cancer cell line
[PMID: 34332400]
MCF7 ED50
18.9 μg/mL
Compound: 9-methoxycanthin-6-one 3N-oxide
Cytotoxicity against human MCF7 cells by SRB assay
Cytotoxicity against human MCF7 cells by SRB assay
[PMID: 14575431]
Melanoma cell ED50
6.5 μg/mL
Compound: 2
Cytotoxicity against human melanoma cells
Cytotoxicity against human melanoma cells
[PMID: 1800638]
Melanoma cell line IC50
3.8 μg/mL
Compound: 30
Cytotoxicity against human Melanoma cell line
Cytotoxicity against human Melanoma cell line
[PMID: 34332400]
P388 ED50
11.7 μg/mL
Compound: 2
Cytotoxicity against mouse P388 cells
Cytotoxicity against mouse P388 cells
[PMID: 1800638]
Molecular Weight

266.25

Formula

C15H10N2O3

CAS No.
SMILES

O=C1N2C3=C(C4=C2C=C(OC)C=C4)C=C[N+]([O-])=C3C=C1

Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
9-Methoxycanthin-6-one-N-oxide
Cat. No.:
HY-N8620
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