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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
29 Results for "
cysteine thiol groups
" in MedChemExpress (MCE) Product Catalog:
Products (29)
29 Results for "cysteine thiol groups" in MCE Product Catalog:
3
3 Cited Publications
Target:
Research Areas:
N-Acetyl-D-cysteine has antioxidant activities and scavenges ROS through the reaction with its thiol group, but cannot enter the glutathione metabolic pathway .
Cat. No.: HY-W087027
CAS No.: 1295584-83-6
Research Areas:
Maleimide-NOTA is a chelate. Maleimide-NOTA can be site-specifically coupled to the hPD-L1 nanobody bearing the Cys-tag. Maleimide-NOTA can specifically conjugate to A20FMDV2 (HY-P1654). The [ 68Ga]Ac-CG6 formed by the conjugation of 68Ga radiolabeled Maleimide-NOTA with A20FMDV2 can be used for PET imaging of αvβ6 integrin-positive pancreatic ductal adenocarcinoma .
Cat. No.: HY-D2906
CAS No.: 1825332-75-9
Target:
Research Areas:
Biotin-BMCC is a Maliemide (HY-W007324) conjugated biotin molecule that has a high affinity for free thiol groups of cysteines .
Cat. No.: HY-D2381
Cat. No.: HY-P11308
CAS No.: 1421680-54-7
Synonyms: 4-Nitrobenzyl mesylate; para-Nitrobenzyl mesylate; PNBM
Target:
Research Areas:
Cardiovascular Disease Neurological Disease Inflammation/Immunology
p-Nitrobenzyl mesylate (4-Nitrobenzyl mesylate) is an alkylating reagent. p-Nitrobenzyl mesylate alkylates thiophosphorylated serine, threonine, tyrosine residues and cysteine thiols, without modifying hydroxyl, amino or carboxylic acid functional groups. p-Nitrobenzyl mesylate generates thiophosphate epitopes on thiophosphorylated substrate proteins for recognition by thiophosphate-specific antibodies. p-Nitrobenzyl mesylate facilitates the identification and purification of kinase substrates. p-Nitrobenzyl mesylate is applicable to studies related to cerebral ischemia-reperfusion injury .
Cat. No.: HY-W106411
CAS No.: 71865-37-7
Synonyms: Dithio-bis-maleimidoethane
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Research Areas:
DTME (dithio-bis-maleimidoethane) is a homobifunctional, maleimide crosslinker specifically designed for conjugation between sulfhydryl groups (-SH). DTME, whose molecular structure consists of two maleimide groups connected by an ethylene disulfide bridge, can specifically react with thiol - containing molecules (such as cysteine residues) to form stable covalent bonds. DTME allows crosslinks that can be cleaved with reducing agents such as DTT (HY-15917). DTME is commonly utilized to explore and characterize protein structure, particularly oligomerization, or protein interactions .
Cat. No.: HY-N9279
CAS No.: 23291-96-5
Synonyms: Monocrotaline pyrrole; MCTP; 3,8-Didehydromonocrotaline
Target:
Cat. No.: HY-W012166
CAS No.: 42014-51-7
Synonyms: NHS-Bromoacetate
Target:
Research Areas:
N-Succinimidyl bromoacetate (NHS-Bromoacetate) is a heterobifunctional crosslinking reagent, mainly used to modify the ɛ-amino group of lysine side chains. By covalently linking its bromoacetyl moiety to the ɛ-amino group of lysine in peptidomimetics, N-Succinimidyl bromoacetate enables their conjugation with thiol-modified nanoparticles via thioether bonds. N-Succinimidyl bromoacetate also performs bromoacetylation modification on carrier proteins, which then forms stable thioether bonds with the thiol groups of cysteine in peptides, thus efficiently preparing soluble peptide-protein conjugates with high substitution ratios. N-Succinimidyl bromoacetate can be used to prepare activated Sepharose derivatives for affinity chromatography, protein affinity labeling reagents, and peptide-protein immunogen conjugates with non-immunogenic linkages. N-Succinimidyl bromoacetate is applicable to studies related to HIV-1 infection and glioblastoma multiforme .
Cat. No.: HY-P4087
CAS No.: 1417221-06-7
Cat. No.: HY-D2002
CAS No.: 1219127-42-0
Cat. No.: HY-W736950A
Target:
Research Areas:
H-L-Cys(MDNPE)-OH hydrochloride is a cysteine derivative with a short peptide sequence attached to the thiol group of cysteine.
Cat. No.: HY-172721
CAS No.: 926905-86-4
Cat. No.: HY-P4087B
Cat. No.: HY-D0151
CAS No.: 174568-67-3
Cat. No.: HY-136386R
CAS No.: 26117-28-2
Category:
Cat. No.: HY-17525
CAS No.: 163269-30-5
Research Areas:
Bethoxazin is a yeast DNA topoisomerase II inhibitor with an IC50 of 5.3 μM, and also a broad-spectrum industrial microbicide and covalent adduct-forming agent. Bethoxazin inhibits the catalytic activity of yeast DNA topoisomerase II by reacting with the key free cysteine thiol group on the enzyme. Bethoxazin forms covalent adducts with molecules containing free thiol groups. Bethoxazin inhibits the growth of yeast cells. Bethoxazin can be used in studies related to the growth of fungi, molds and algae .
Cat. No.: HY-W394551
CAS No.: 1442447-48-4
Target:
Research Areas:
Methyl 3,4-dibromo-2,5-dioxo-2,5-dihydro-1H-pyrrole-1-carboxylate is a small pyrrolidone molecule which features two bromine atoms and a methyl ester. The unsaturated dibromo motif is a covalent ligand for thiol groups, and may be used to label cysteine residues in proteins. The presence of two leaving groups on this molecule allows this linker to bind two thiols at a time. The methyl ester can be saponified to link this molecule to amines to form larger structures.
Cat. No.: HY-D1404
CAS No.: 2100286-15-3
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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
