Mal-amide-PEG8-Val-Cit-PAB-PNP
Based on 1 Customer Validation
Mal-amide-PEG8-Val-Cit-PAB-PNP is a cleavable ADC linker. Mal-amide-PEG8-Val-Cit-PAB-PNP consists of maleimide, a PEG spacer, Val-Cit dipeptide, PAB and PNP carbonate, and is applicable for the synthesis of ADCs.
For research use only. We do not sell to patients.
- Purity: 98.05%
- CAS No.: 1964490-09-2
- Formula: C51H74N8O20
- Molecular Weight:1119.17
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
Chemical Information
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CAS No. 1964490-09-2
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Appearance Solid
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Molecular Weight 1119.17
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Formula C51H74N8O20
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Color White to off-white
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SMILES
O=C(C=CC1=O)N1CCC(NCCOCCOCCOCCOCCOCCOCCOCCOCCC(N[C@@H](C(C)C)C(N[C@@H](CCCNC(N)=O)C(NC2=CC=C(C=C2)COC(OC3=CC=C(C=C3)[N+]([O-])=O)=O)=O)=O)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 30 mg/mL (26.81 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (244 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.8935 mL | 4.4676 mL | 8.9352 mL | 22.3380 mL |
| 5 mM | 0.1787 mL | 0.8935 mL | 1.7870 mL | 4.4676 mL | |
| 10 mM | 0.0894 mL | 0.4468 mL | 0.8935 mL | 2.2338 mL | |
| 15 mM | 0.0596 mL | 0.2978 mL | 0.5957 mL | 1.4892 mL | |
| 20 mM | 0.0447 mL | 0.2234 mL | 0.4468 mL | 1.1169 mL | |
| 25 mM | 0.0357 mL | 0.1787 mL | 0.3574 mL | 0.8935 mL |