Mal-amide-PEG8-Val-Cit-PAB-OH
Mal-amide-PEG8-Val-Cit-PAB-OH is a cleavable ADC linker featuring a maleimide, a hydrophilic PEG spacer, a Val-Cit dipeptide, and a PAB functional group. Maleimide is used to covalently bind free thiols on the cysteine residues of proteins. The Val-Cit dipeptide is cleaved by cellular proteases within the cell to allow for efficient payload delivery with the help of the PAB structure.
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- CAS. Nr.: 2387738-43-2
- Formel: C44H71N7O16
- Molecular Weight:954.07
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
Chemical Information
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CAS. Nr. 2387738-43-2
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Molecular Weight 954.07
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Formel C44H71N7O16
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SMILES
CC(C)[C@@H](C(N[C@H](C(NC1=CC=C(C=C1)CO)=O)CCCNC(N)=O)=O)NC(CCOCCOCCOCCOCCOCCOCCOCCOCCNC(CCN(C(C=C2)=O)C2=O)=O)=O
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Mal-amide-PEG8-Val-Cit-PAB-OH Related Classifications
HY-152919 Related Classifications
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