Mal-amide-PEG8-Val-Cit-PAB-OH
Mal-amide-PEG8-Val-Cit-PAB-OH is a cleavable ADC linker featuring a maleimide, a hydrophilic PEG spacer, a Val-Cit dipeptide, and a PAB functional group. Maleimide is used to covalently bind free thiols on the cysteine residues of proteins. The Val-Cit dipeptide is cleaved by cellular proteases within the cell to allow for efficient payload delivery with the help of the PAB structure.
For research use only. We do not sell to patients.
- CAS No.: 2387738-43-2
- Formula: C44H71N7O16
- Molecular Weight:954.07
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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CAS No. 2387738-43-2
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Molecular Weight 954.07
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Formula C44H71N7O16
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SMILES
CC(C)[C@@H](C(N[C@H](C(NC1=CC=C(C=C1)CO)=O)CCCNC(N)=O)=O)NC(CCOCCOCCOCCOCCOCCOCCOCCOCCNC(CCN(C(C=C2)=O)C2=O)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)