1. Immunology/Inflammation
    NF-κB
    Metabolic Enzyme/Protease
  2. Reactive Oxygen Species
  3. N-Acetyl-D-cysteine

N-Acetyl-D-cysteine 

Cat. No.: HY-136386 Purity: >97.0%
Handling Instructions

N-Acetyl-D-cysteine has antioxidant activities and scavenges ROS through the reaction with its thiol group, but cannot enter the glutathione metabolic pathway.

For research use only. We do not sell to patients.

N-Acetyl-D-cysteine Chemical Structure

N-Acetyl-D-cysteine Chemical Structure

CAS No. : 26117-28-2

Size Price Stock Quantity
10 mM * 1  mL in Water USD 83 In-stock
Estimated Time of Arrival: December 31
25 mg USD 75 In-stock
Estimated Time of Arrival: December 31
50 mg USD 90 In-stock
Estimated Time of Arrival: December 31
100 mg USD 150 In-stock
Estimated Time of Arrival: December 31
250 mg USD 250 In-stock
Estimated Time of Arrival: December 31
500 mg USD 370 In-stock
Estimated Time of Arrival: December 31
1 g   Get quote  
5 g   Get quote  

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Customer Review

Based on 1 publication(s) in Google Scholar

Top Publications Citing Use of Products
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Description

N-Acetyl-D-cysteine has antioxidant activities and scavenges ROS through the reaction with its thiol group, but cannot enter the glutathione metabolic pathway[1].

In Vitro

N-Acetyl-D-cysteine (20 mM; 1 hour pretreatment; 12 hours) does not increase intracellular GSH levels, but GSH monoester does. D-NAC can not enhance hypoxic apoptosis. This demonstrate that GSH rather than D-NAC or NAC is responsible for enhancing hypoxic apoptosis[3].

Molecular Weight

163.19

Formula

C₅H₉NO₃S

CAS No.

26117-28-2

SMILES

SC[[email protected]](C(O)=O)NC(C)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Solvent & Solubility
In Vitro: 

H2O : 250 mg/mL (1531.96 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 6.1278 mL 30.6391 mL 61.2783 mL
5 mM 1.2256 mL 6.1278 mL 12.2557 mL
10 mM 0.6128 mL 3.0639 mL 6.1278 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    D-NAC was dissolved in physiological saline at a concentration of 6.13 mM (1 mg/ml), and pH adjusted to 7.5 by NaOH[2].

References
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Keywords:

N-Acetyl-D-cysteineReactive Oxygen SpeciesMEFmurineembryonicfibroblastglutathioneGSHInhibitorinhibitorinhibit

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N-Acetyl-D-cysteine
Cat. No.:
HY-136386
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