Search Result

Results for "

diamide

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Apoptosis (4) Calcium Channel (2) Carbonic Anhydrase (3) CXCR (2) Drug Intermediate (1) Endogenous Metabolite (6) Environmental Pollutants (2) ERK (3) Insecticide (5) Insulin Receptor (1) Isotope-Labeled Compounds (4) Melanocortin Receptor (1) MOFs (2) Neuropeptide Y Receptor (2) Parasite (4) PROTAC Linkers (1) Reactive Oxygen Species (ROS) (1) Reference Standards (3) Trk Receptor (1)
By Research Areas:	Cancer (8) Cardiovascular Disease (5) Infection (3) Metabolic Disease (2) Neurological Disease (3)
Click Chemistry:	PROTAC Synthesis (1) BCN (1)

Inhibitors & Agonists

Peptides

Natural
Products

Isotope-Labeled Compounds

Click Chemistry

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-Y0271

Urea 5+ Cited Publications Carbonyl diamide	Environmental Pollutants Apoptosis Endogenous Metabolite Carbonic Anhydrase ERK	Cardiovascular Disease Cancer
Urea is a powerful protein denaturant via both direct and indirect mechanisms . A potent emollient and keratolytic agent . Used as a diuretic agent. Blood urea nitrogen (BUN) has been utilized to evaluate renal function . Widely used in fertilizers as a source of nitrogen and is an important raw material for the chemical industry.

HY-Y0271S

Urea-15N2 Carbonyl diamide-¹⁵N₂	Endogenous Metabolite	Cardiovascular Disease Cancer
Urea- ¹⁵N₂ is the ¹⁵N-labeled Urea. Urea is a powerful protein denaturant via both direct and indirect mechanisms . A potent emollient and keratolytic agent . Used as a diuretic agent. Blood urea nitrogen (BUN) has been utilized to evaluate renal function . Widely used in fertilizers as a source of nitrogen and is an important raw material for the chemical industry.

HY-P4070

Insulin icodec	Insulin Receptor	Metabolic Disease
Insulin icodec is an Insulin (HY-P0035) analog that strongly but reversibly binds to albumin. Insulin icodec has long plasma half-life. Insulin icodec modulates insulin receptor activity, controls blood glucose levels, reduces HbA_1c levels, and binds reversibly to human serum albumin. Insulin icodec can be used for the research of type 2 diabetes mellitus .

HY-Y0271S2

Urea-13C,15N2 Carbonyl diamide-¹³C,¹⁵N₂	Endogenous Metabolite	Cardiovascular Disease
Urea- ¹³C, ¹⁵N₂ is the ¹³C and ¹⁵N labeled Urea . Urea is a powerful protein denaturant via both direct and indirect mechanisms . A potent emollient and keratolytic agent . Used as a diuretic agent. Blood urea nitrogen (BUN) has been utilized to evaluate renal function . Widely used in fertilizers as a source of nitrogen and is an important raw material for the chemical industry.

HY-164322

Cyproflanilide	Insecticide	Others
Cyproflanilide is a meta-diamide insecticide. Cyproflanilide exhibits potent insecticidal activity against third Chilo suppressalis and Spodoptera frugiperda larvae. Cyproflanilide can be used for the research of insect pests .

HY-P1103

CTCE-9908 1 Publications Verification	CXCR	Cancer
CTCE-9908 is a potent and selective CXCR4 antagonist. CTCE-9908 induces mitotic catastrophe, cytotoxicity and inhibits migration in CXCR4-expressing ovarian cancer cells .

HY-118877

Urea-13C 1 Publications Verification Carbonyl diamide-¹³C	Isotope-Labeled Compounds	Infection
Urea- ¹³C is the ¹³C labelled urea. The Urea- ¹³C breath test ( ¹³C-UBT) is one of the best methods for the diagnosis of Helicobacter pylori infection .

HY-Y0271S1

Urea-d4 Carbonyl diamide-d₄	Endogenous Metabolite	Others
Urea-d₄ is the deuterium labeled Urea . Urea is a powerful protein denaturant via both direct and indirect mechanisms . A potent emollient and keratolytic agent . Used as a diuretic agent. Blood urea nitrogen (BUN) has been utilized to evaluate renal function . Widely used in fertilizers as a source of nitrogen and is an important raw material for the chemical industry.

HY-12779

Cyantraniliprole 1 Publications Verification HGW-86	Environmental Pollutants Parasite	Others
Cyantraniliprole (HGW-86) is a potent and selective aniline receptor activator with oral activity. Cyantraniliprole has insecticidal and antioxidant activity .

HY-160758

J9Z38	Insecticide	Others
J9Z38 is a metabolite of Cyantraniliprole (HY-12779), a broad-spectrum agrochemical insecticide belonging to the anthranilic diamide insecticide class. Cyantraniliprole effectively controls the growth of various pests on fruits, vegetables, cereals and other crops. Thus, J9Z38 is a key indicator for indirect detection and evaluation of Cyantraniliprole residue levels .

HY-Y0271R

Urea (Standard) Carbonyl diamide (Standard)	Carbonic Anhydrase Reference Standards Endogenous Metabolite ERK Apoptosis	Cardiovascular Disease Cancer
Urea (Standard) is the analytical standard of Urea. This product is intended for research and analytical applications. Urea is a powerful protein denaturant via both direct and indirect mechanisms . A potent emollient and keratolytic agent . Used as a diuretic agent. Blood urea nitrogen (BUN) has been utilized to evaluate renal function . Widely used in fertilizers as a source of nitrogen and is an important raw material for the chemical industry.

HY-W339331

Flubendiamide NNI-0001	Insecticide Calcium Channel Reactive Oxygen Species (ROS) Apoptosis	Infection Metabolic Disease
Flubendiamide (NNI-0001) is an orally active phthalic diamide insecticide that acts by targeting insect ryanodine receptors (RyRs), causing insect muscle dysfunction, paralysis and death. Flubendiamide disrupts molting, metamorphosis and reproductive processes, induces oxidative stress by increasing the levels of ROS/RNS, MDA and 8OHdG and decreasing the levels of SOD, CAT and GST, activates the CncC/Maf apoptosis pathway, impairs calcium homeostasis, promotes adipogenesis, increases triglyceride accumulation, and upregulates the expression of regulatory factors for adipocyte differentiation and adipogenesis .

HY-133510

Bis-BCN-PEG1-diamide	PROTAC Linkers	Cancer
Bis-BCN-PEG1-diamide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Bis-BCN-PEG1-diamide is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-P1103A

CTCE-9908 TFA	CXCR	Cancer
CTCE-9908 TFA is a potent and selective CXCR4 antagonist. CTCE-9908 TFA induces mitotic catastrophe, cytotoxicity and inhibits migration in CXCR4-expressing ovarian cancer cells .

HY-P4757

N1-Glutathionyl-spermidine disulfide	Parasite	Others
N1-Glutathionyl-spermidine disulfide is a substrate of trypanothione reductase .

HY-P11293

DOTA-GGNle-CycMSHhex	Melanocortin Receptor	Cancer
DOTA-GGNle-CycMSHhex is a melanocortin-1 receptor (MC1R)-targeting peptide that can be radionuclide-labeled for melanoma imaging .

HY-P1321

GR231118 1229U91; GW1229	Neuropeptide Y Receptor	Neurological Disease
GR231118, an analogue of the C-terminus of neuropeptide Y, is a potent , competitive and relative seletive antagonist at human neuropeptide Y Y receptor with a pK_i of 10.4. GR231118 a potent agonist at the human neuropeptide Y Y4 receptor (pEC₅₀=8.6; pK_i=9.6) and a weak agonist at the human and rat neuropeptide YY2 and Y5 receptors. GR231118 also has high affinity for the mouse neuropeptide Y Y6 receptor (pK_i= 8.8) .

HY-W010596S

Malonamide-13C3 METHANEDICARBOXYLIC ACID diamide-¹³C₃	Isotope-Labeled Compounds	Others
Malonamide- ¹³C₃ (METHANEDICARBOXYLIC ACID DIAMIDE- ¹³C₃) is the ¹³C-labeled Malonamide (HY-W010596).

HY-12779R

Cyantraniliprole (Standard) HGW-86 (Standard)	Reference Standards Parasite	Others
Cyantraniliprole (Standard) is the analytical standard of Cyantraniliprole. This product is intended for research and analytical applications. Cyantraniliprole (HGW-86) is a potent and selective aniline receptor activator with oral activity. Cyantraniliprole has insecticidal and antioxidant activity .

HY-156082

RyRs activator 3	Parasite Calcium Channel	Others
RyRs activator 3 (compound A4) is an effective insecticide against diamondback moths (M. separata) and diamondback moths (P. xylostella). The LC50 value of RyRs activator 3 against diamondback moth is 3.27 mg/L. RyRs activator 3 can bind to ryanodine receptor, increase cytoplasmic Ca2+ concentration, and produce biological toxicity .

HY-P1321A

GR231118 TFA 1229U91 TFA; GW1229 TFA	Neuropeptide Y Receptor	Neurological Disease
GR231118 TFA, an analogue of the C-terminus of neuropeptide Y, is a potent , competitive and relative seletive antagonist at human neuropeptide YY receptor with a pK_i of 10.4. GR231118 a potent agonist at the human neuropeptide YY4 receptor (pEC₅₀=8.6; pK_i=9.6) and a weak agonist at the human and rat neuropeptide Y Y2 and Y5 receptors. GR231118 also has high affinity for the mouse neuropeptide YY6 receptor (pK_i= 8.8) .

HY-W112943

P-(1,1-Dimethylethyl)-N,N′-bis(1-methylethyl)phosphonic diamide	MOFs	Others
P-(1,1-Dimethylethyl)-N,N′-bis(1-methylethyl)phosphonic diamide is a metal-organic framework (MOF).

HY-W150770

Isophthalamide Isophthalic acid diamide	Drug Intermediate	Others
Isophthalamide (Isophthalic acid diamide) is a widely used chemical scaffold for the design of high-performance fluorescent chemosensors.Isophthalamide, with its inherent hydrogen-bond-donating properties and tunable chelating cavity, enables highly selective recognition and detection of various analytes ranging from inorganic ions to complex organic molecules.Isophthalamide can be incorporated with various fluorophores to develop sensors displaying “turn-on” or “turn-off” signal responses.Isophthalamide-based sensors are thus capable of detecting diverse analytes including metal ions, anions, neutral molecules, pharmaceuticals, and explosives .

HY-W339331R

Flubendiamide (Standard) NNI-0001 (Standard)	Insecticide Reference Standards	Others
Flubendiamide (Standard) is the analytical standard of Flubendiamide. This product is intended for research and analytical applications. Flubendiamide is a 1,2-diamide insecticide via action mode of action action by activating the ryanodine receptor .

HY-W075595

(2S,2'S)-2,2'-(1,3,8,10-Tetraoxo-1,3,8,10-tetrahydroanthra[2,1,9-def:6,5,10-d'e'f']diisoquinoline-2,9-diyl)dipropionic acid N, N'-bis (L-alanine) perylene diamide	MOFs	Others
(2S,2'S)-2,2'-(1,3,8,10-Tetraoxo-1,3,8,10-tetrahydroanthra[2,1,9-def:6,5,10-d'e'f']diisoquinoline-2,9-diyl)dipropionic acid (N, N'-bis (L-alanine) perylene diamide) is a metal-organic framework (MOF).

HY-W727480

Tetrachlorantraniliprole	Insecticide	Infection
Tetrachlorantraniliprole is an anthranilic diamide insecticide that shows no significant affinity to the key odorant-binding proteins (DhelOBP4/DhelOBP21) of Dastarcus helophoroides .

HY-W010465S

N,N-Dimethylsulfamide-d6 N,N-dimethylsulfuric diamide-d₆	Isotope-Labeled Compounds	Others
N,N-Dimethylsulfamide-d₆ is the deuterium labeled N,N-Dimethylsulfamide .

HY-Y0271S3

Urea-13C,15N Carbonyl diamide-¹³C,¹⁵N	Isotope-Labeled Compounds Carbonic Anhydrase Endogenous Metabolite ERK Apoptosis	Cardiovascular Disease Cancer
Urea- ¹³C, ¹⁵N is the ¹³C- and ¹⁵N-labeled Urea (HY-Y0271). Urea is a powerful protein denaturant via both direct and indirect mechanisms. A potent emollient and keratolytic agent. Used as a diuretic agent. Blood urea nitrogen (BUN) has been utilized to evaluate renal function. Widely used in fertilizers as a source of nitrogen and is an important raw material for the chemical industry .

HY-P11480

TrkA/NGF-IN-1	Trk Receptor	Neurological Disease
TrkA/NGF-IN-1 (Peptide 19) is an inhibitor of protein-protein interactions between TrkA and NGF (IC₅₀: 21 nM for human TrkA in PathHunter assay). TrkA/NGF-IN-1 shows an analgesic effect in a rat incisional pain model .

Cat. No.	Product Name	Target	Research Area

HY-P4070

Insulin icodec	Insulin Receptor	Metabolic Disease
Insulin icodec is an Insulin (HY-P0035) analog that strongly but reversibly binds to albumin. Insulin icodec has long plasma half-life. Insulin icodec modulates insulin receptor activity, controls blood glucose levels, reduces HbA_1c levels, and binds reversibly to human serum albumin. Insulin icodec can be used for the research of type 2 diabetes mellitus .

HY-P1103

CTCE-9908 1 Publications Verification	CXCR	Cancer
CTCE-9908 is a potent and selective CXCR4 antagonist. CTCE-9908 induces mitotic catastrophe, cytotoxicity and inhibits migration in CXCR4-expressing ovarian cancer cells .

HY-P1103A

CTCE-9908 TFA	CXCR	Cancer
CTCE-9908 TFA is a potent and selective CXCR4 antagonist. CTCE-9908 TFA induces mitotic catastrophe, cytotoxicity and inhibits migration in CXCR4-expressing ovarian cancer cells .

HY-P4757

N1-Glutathionyl-spermidine disulfide	Parasite	Others
N1-Glutathionyl-spermidine disulfide is a substrate of trypanothione reductase .

HY-P11293

DOTA-GGNle-CycMSHhex	Melanocortin Receptor	Cancer
DOTA-GGNle-CycMSHhex is a melanocortin-1 receptor (MC1R)-targeting peptide that can be radionuclide-labeled for melanoma imaging .

HY-P1321

GR231118 1229U91; GW1229	Neuropeptide Y Receptor	Neurological Disease
GR231118, an analogue of the C-terminus of neuropeptide Y, is a potent , competitive and relative seletive antagonist at human neuropeptide Y Y receptor with a pK_i of 10.4. GR231118 a potent agonist at the human neuropeptide Y Y4 receptor (pEC₅₀=8.6; pK_i=9.6) and a weak agonist at the human and rat neuropeptide YY2 and Y5 receptors. GR231118 also has high affinity for the mouse neuropeptide Y Y6 receptor (pK_i= 8.8) .

HY-P1321A

GR231118 TFA 1229U91 TFA; GW1229 TFA	Neuropeptide Y Receptor	Neurological Disease
GR231118 TFA, an analogue of the C-terminus of neuropeptide Y, is a potent , competitive and relative seletive antagonist at human neuropeptide YY receptor with a pK_i of 10.4. GR231118 a potent agonist at the human neuropeptide YY4 receptor (pEC₅₀=8.6; pK_i=9.6) and a weak agonist at the human and rat neuropeptide Y Y2 and Y5 receptors. GR231118 also has high affinity for the mouse neuropeptide YY6 receptor (pK_i= 8.8) .

HY-P11480

TrkA/NGF-IN-1	Trk Receptor	Neurological Disease
TrkA/NGF-IN-1 (Peptide 19) is an inhibitor of protein-protein interactions between TrkA and NGF (IC₅₀: 21 nM for human TrkA in PathHunter assay). TrkA/NGF-IN-1 shows an analgesic effect in a rat incisional pain model .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-Y0271

Urea 5+ Cited Publications Carbonyl diamide	Structural Classification Natural Products Microorganisms Classification of Application Fields Endogenous metabolite Disease Research Fields Biological Pesticide Research Source Classification Cancer Agricultural Research	Environmental Pollutants Apoptosis Endogenous Metabolite Carbonic Anhydrase ERK
Urea is a powerful protein denaturant via both direct and indirect mechanisms . A potent emollient and keratolytic agent . Used as a diuretic agent. Blood urea nitrogen (BUN) has been utilized to evaluate renal function . Widely used in fertilizers as a source of nitrogen and is an important raw material for the chemical industry.

HY-Y0271R

Urea (Standard) Carbonyl diamide (Standard)	Structural Classification Natural Products Microorganisms Endogenous metabolite Source Classification	Carbonic Anhydrase Reference Standards Endogenous Metabolite ERK Apoptosis
Urea (Standard) is the analytical standard of Urea. This product is intended for research and analytical applications. Urea is a powerful protein denaturant via both direct and indirect mechanisms . A potent emollient and keratolytic agent . Used as a diuretic agent. Blood urea nitrogen (BUN) has been utilized to evaluate renal function . Widely used in fertilizers as a source of nitrogen and is an important raw material for the chemical industry.

Cat. No.	Product Name	Chemical Structure

HY-Y0271S

Urea-15N2
Urea- ¹⁵N₂ is the ¹⁵N-labeled Urea. Urea is a powerful protein denaturant via both direct and indirect mechanisms . A potent emollient and keratolytic agent . Used as a diuretic agent. Blood urea nitrogen (BUN) has been utilized to evaluate renal function . Widely used in fertilizers as a source of nitrogen and is an important raw material for the chemical industry.

HY-Y0271S2

Urea-13C,15N2
Urea- ¹³C, ¹⁵N₂ is the ¹³C and ¹⁵N labeled Urea . Urea is a powerful protein denaturant via both direct and indirect mechanisms . A potent emollient and keratolytic agent . Used as a diuretic agent. Blood urea nitrogen (BUN) has been utilized to evaluate renal function . Widely used in fertilizers as a source of nitrogen and is an important raw material for the chemical industry.

HY-118877

Urea-13C 1 Publications Verification
Urea- ¹³C is the ¹³C labelled urea. The Urea- ¹³C breath test ( ¹³C-UBT) is one of the best methods for the diagnosis of Helicobacter pylori infection .

HY-Y0271S1

Urea-d4
Urea-d₄ is the deuterium labeled Urea . Urea is a powerful protein denaturant via both direct and indirect mechanisms . A potent emollient and keratolytic agent . Used as a diuretic agent. Blood urea nitrogen (BUN) has been utilized to evaluate renal function . Widely used in fertilizers as a source of nitrogen and is an important raw material for the chemical industry.

HY-W010596S

Malonamide-13C3
Malonamide- ¹³C₃ (METHANEDICARBOXYLIC ACID DIAMIDE- ¹³C₃) is the ¹³C-labeled Malonamide (HY-W010596).

HY-W010465S

N,N-Dimethylsulfamide-d6
N,N-Dimethylsulfamide-d₆ is the deuterium labeled N,N-Dimethylsulfamide .

HY-Y0271S3

Urea-13C,15N

Urea- ¹³C, ¹⁵N is the ¹³C- and ¹⁵N-labeled Urea (HY-Y0271). Urea is a powerful protein denaturant via both direct and indirect mechanisms. A potent emollient and keratolytic agent. Used as a diuretic agent. Blood urea nitrogen (BUN) has been utilized to evaluate renal function. Widely used in fertilizers as a source of nitrogen and is an important raw material for the chemical industry .

Cat. No.	Product Name		Classification

HY-133510

Bis-BCN-PEG1-diamide		PROTAC Synthesis BCN
Bis-BCN-PEG1-diamide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Bis-BCN-PEG1-diamide is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

Inquiry Online

Your information is safe with us. * Required Fields.

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社重松貿易株式会社
Salutation			Country or Region *
Applicant Name *			Organization Name *
Department *
Email Address *			Product Name *
Cat. No.			Requested quantity *
Phone Number *
Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent:

diamide

Inhibitors & Agonists

Peptides

NaturalProducts

Isotope-Labeled Compounds

Click Chemistry

Natural
Products