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Cat. No.: HY-P11293

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DOTA-GGNle-CycMSHhex

DOTA-GGNle-CycMSHhex is a melanocortin-1 receptor (MC1R)-targeting peptide that can be radionuclide-labeled for melanoma imaging.

For research use only. We do not sell to patients.

CAS No.: 1309855-53-5
Formula: C₆₈H₉₉N₂₁O₁₇
Molecular Weight:1482.64

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

DOTA-GGNle-CycMSHhex Chemical Structure

CAS No.: 1309855-53-5

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

DOTA-GGNle-CycMSHhex is a melanocortin-1 receptor (MC1R)-targeting peptide that can be radionuclide-labeled for melanoma imaging^[1].

All Melanocortin Receptor Isoforms :

Chemical Information

CAS No. 1309855-53-5
Molecular Weight 1482.64
Formula C₆₈H₉₉N₂₁O₁₇
Sequence

{DOTA}-Gly-Gly-{Nle}-Asp-His-{dPhe}-Arg-Trp-Lys-NH2 (amide bridge:Asp4-Lys9)
Sequence Shortening

{DOTA}-GG-{Nle}-DH-{dPhe}-RWK-NH2 (amide bridge:Asp4-Lys9)
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (258 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Yang J, et al. 68Ga-DOTA-GGNle-CycMSHhex targets the melanocortin-1 receptor for melanoma imaging. Sci Transl Med. 2018 Nov 7;10(466):eaau4445. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
Chemical Information
Purity & Documentation
References

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DOTA-GGNle-CycMSHhex

All Melanocortin Receptor Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

DOTA-GGNle-CycMSHhex Related Classifications

HY-P11293 Related Classifications