Urea (Standard)
Based on 1 Customer Validation
Urea (Standard) is the analytical standard of Urea. This product is intended for research and analytical applications. Urea is a powerful protein denaturant via both direct and indirect mechanisms. A potent emollient and keratolytic agent. Used as a diuretic agent. Blood urea nitrogen (BUN) has been utilized to evaluate renal function. Widely used in fertilizers as a source of nitrogen and is an important raw material for the chemical industry.
For research use only. We do not sell to patients.
- Purity: 99.87%
- CAS No.: 57-13-6
- Formula: CH4N2O
- Molecular Weight:60.06
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Product Information
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 57-13-6
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Appearance Solid
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Molecular Weight 60.06
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Formula CH4N2O
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Color White to off-white
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SMILES
NC(N)=O
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Synonyms
Carbonyl diamide (Standard)
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
[1]. Bennion BJ, et al. The molecular basis for the chemical denaturation of proteins by urea. Proc Natl Acad Sci U S A. 2003 Apr 29;100(9):5142-7. [Content Brief]
[2]. Pan M, et al. Urea: a comprehensive review of the clinical literature. Dermatol Online J. 2013 Nov 15;19(11):20392. [Content Brief]
[3]. Wang H, et al. Urea. Subcell Biochem. 2014;73:7-29. [Content Brief]
[4]. Michea L, et al., Cell cycle delay and apoptosis are induced by high salt and urea in renal medullary cells. Am J Physiol Renal Physiol. 2000 Feb;278(2):F209-18. [Content Brief]
[5]. Zhang Z, et al., High urea and NaCl carbonylate proteins in renal cells in culture and in vivo, and high urea causes 8-oxoguanine lesions in their DNA. Proc Natl Acad Sci U S A. 2004 Jun 22;101(25):9491-6. [Content Brief]
[6]. Prabhakar SS, et al., Urea inhibits inducible nitric oxide synthase in macrophage cell line. Am J Physiol. 1997 Dec;273(6):C1882-8. [Content Brief]
[7]. Yang XY, et al., ERK activation by urea in the renal inner medullary mIMCD3 cell line. Am J Physiol. 1999 Aug;277(2):F176-85. [Content Brief]
[8]. Ogino Y, et al., Effects of chronic, urea-induced osmotic diuresis on kidney weight and function in rats. Diabetologia. 1994 Mar;37(3):225-31. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)