25 Results for "

microbial secondary metabolite

" in MedChemExpress (MCE) Product Catalog:
Products (25)

25 Results for "microbial secondary metabolite" in MCE Product Catalog:

Cat. No.: HY-48814
CAS No.: 570-63-8
Target:  

Bacterial FXR

Research Areas:  

Infection Inflammation/Immunology

3-Epideoxycholic acid is a secondary bile acid and a microbial metabolite of Deoxycholic acid (HY-N0593). 3-Epideoxycholic acid targets FXR in dendritic cells, reduces their immunostimulatory properties, promotes the generation of Treg cells, and exerts anti-inflammatory activity. 3-Epideoxycholic acid can promote the growth of the bacterium Bacteroides. 3-Epideoxycholic acid can be used in research related to inflammatory and immune diseases as well as bacterial infections .
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Cat. No.: HY-Y0669S
CAS No.: 790612-94-1
Pipecolic acid-d9 is the deuterium labeled Pipecolic acid. Pipecolic acid is a metabolite of lysine and an important precursor for many useful microbial secondary metabolites. Pipecolic acid slows ferroptosis in diabetic retinopathy by inhibiting the YAP-GPX4 signaling pathway. In addition, Pipecolic acid can be used as a diagnostic marker for pyridoxine-dependent epilepsy .
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Cat. No.: HY-Y0669R
CAS No.: 535-75-1
Pipecolic acid (Standard) is the analytical standard of Pipecolic acid. This product is intended for research and analytical applications. Pipecolic acid is a metabolite of lysine and an important precursor for many useful microbial secondary metabolites. Pipecolic acid slows ferroptosis in diabetic retinopathy by inhibiting the YAP-GPX4 signaling pathway. In addition, Pipecolic acid can be used as a diagnostic marker for pyridoxine-dependent epilepsy .
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Cat. No.: HY-W751002
CAS No.: 118063-79-9
Synonyms: (+)-Orthosporin
Orthosporin ((+)-Orthosporin), a phytotoxic isocoumarin compound, is a microbial secondary metabolite. Orthosporin can be isolated from the endophytic fungus Lasiodiplodia tbeobromae. Orthosporin has potent antibacterial activity against B. subtilis, E. coli and P. aeruginosa. Orthosporin also has antioxidant activity against DPPH radical and antiviral activities with inhibition of HIV-1 reverse transcriptase activity .
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Cat. No.: HY-N16441
CAS No.: 26548-70-9
Pulvic acid (Compound 3), a butenolide, is a microbial secondary metabolite. Pulvic acid can be isolated from the marine-derived fungus Aspergillus terreus Gwq-48. Pulvic acid has significant antiviral activity with an IC50 of 29.1 μg/mL for influenza A H1N1 virus. Pulvic acid can be used for influenza virus infections research .
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Cat. No.: HY-158721
CAS No.: 1214268-60-6
Synonyms: Marinamide
Penicinoline (Marinamide) (Compound 1), a pyrrolyl 4-quinolinone alkaloid, is a microbial secondary metabolite. Penicinoline can be isolated from endophytic fungus Penicillium sp. Penicinoline has antimalarial activity against Chloroquine (HY-17589A) sensitive strain (pf3d7) and against Chloroquine resistant strain (pfDd2) of plasmodium falciparum. Penicinoline also has strong insecticidal activity against Aphis gossypii and selective anticancer effect with significant cytotoxicity for 95-D and HepG2 cells .
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Cat. No.: HY-N14927
CAS No.: 396729-23-0
Target:  

Proteasome

Phepropeptin A, a microbial secondary metabolite, is a proteasome inhibitor with an IC50 of 21 μg/mL .
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Cat. No.: HY-N14928
CAS No.: 396729-24-1
Target:  

Proteasome

Phepropeptin B, a microbial secondary metabolite, is a proteasome inhibitor with an IC50 of 11 μg/mL .
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Cat. No.: HY-N14929
CAS No.: 396729-25-2
Target:  

Proteasome

Phepropeptin C, a microbial secondary metabolite, is a proteasome inhibitor with an IC50 of 12.5 μg/mL .
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Cat. No.: HY-N14940
CAS No.: 396729-26-3
Target:  

Proteasome

Phepropeptin D, a microbial secondary metabolite, is a proteasome inhibitor with an IC50 of 7.8 μg/mL .
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Cat. No.: HY-N16394
CAS No.: 103614-68-2
4-Hydroxyscytalone (Compound 3) is a microbial secondary metabolite. 4-Hydroxyscytalone can be isolated from the oak fungus Diplodia corticola. 4-Hydroxyscytalone has toxicity against Artemia salina with a LC50 of 90.6 μ/mL, but no significant antifungal activity. 4-Hydroxyscytalone can be used for cancer therapy research .
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Cat. No.: HY-N16445
CAS No.: 235090-14-9
Synonyms: (-)-Strevertene A
Strevertene A ((-)-Strevertene A) (Compound 1), a pentaene macrolide, is a microbial secondary metabolite. Strevertene A is an antibiotic and has a potent antifungal activity. Strevertene A significantly inhibits the mycelial growth of phytopathogenic fungi (such as Alternaria mali, Aspergillus oryzae and Cylindrocarpon destructans) with IC50s of 4-16 μg/mL. Strevertenes A can strongly prevent Fusarium wilt development on tomato plants .
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Cat. No.: HY-N16457
CAS No.: 1661837-02-0
5,6-Dihydro-6-hydroxypenicillic acid (Compound 6) is a microbial secondary metabolite. 5,6-Dihydro-6-hydroxypenicillic acid can be isolated from the endophytic fungus Talaromyces sp. CPCC 400783 of Reynoutria japonica Houtt. 5,6-Dihydro-6-hydroxypenicillic acid has antiviral activity against influenza A virus with an IC50 of 65.45 μM .
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Cat. No.: HY-N16442
CAS No.: 428439-25-2
Pyrrocidine B (Compound 6), an alkaloid, is a microbial secondary metabolite. Pyrrocidine B can be isolated from the endophytic fungus Neonectria ramulariae Wollenw KS-246. Pyrrocidine B has significant cytotoxicity against leukemia cells (IC50 of 4.6  μM for HL60 cells) with a weak Prolyl oligopeptidase (POP) inhibitory activity .
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Cat. No.: HY-N12106
CAS No.: 1421941-29-8
Synonyms: Fumicycline
Neosartoricin (Fumicycline) (Compound 3), a prenylated anthracenone, is a microbial secondary metabolite. Neosartoricin can be isolated from Aspergillus fumigatus and Neosartorya fischeri. Neosartoricin has immunosuppressive activity, and significantly inhibits T-cell proliferative activity with an IC50 of 3 μM. Neosartoricin may be beneficial to fungal defense, facilitating infection through suppressing the host adaptive immunity without involvement of primary virulence .
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Cat. No.: HY-119675
CAS No.: 1222-90-8
Albonoursin, a microbial secondary metabolite, is an antibacterial peptide. Albonoursin displays antibacterial and antitumor activities .
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Cat. No.: HY-N5158B
CAS No.: 108864-61-5
(5S)-Neosamine C is an aminocyclic alcohol antibiotic derived from microbial secondary metabolites. (5S)-Neosamine C has a cyclized structure and can be used for biosynthesis of Neomycins (HY-B0470).
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Cat. No.: HY-N16423
CAS No.: 866954-29-2
Metenaticin A (Compound 8), a polyketide, is a microbial secondary metabolite. Metenaticin A can be isolated from Streptomyces violaceoruber TU22 .
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Cat. No.: HY-N13891
CAS No.: 271574-41-5
Arisostatin A, a microbial secondary metabolite, is an antibiotic against Gram-positive bacteria and shown to possess potent anti-tumor properties. Arisostatin A induces apoptosis through the activation of caspase-3 and reactive oxygen species (ROS) generation in AMC-HN-4 cells .
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Cat. No.: HY-N16443
CAS No.: 915403-42-8
Sporminarin A (Compound 1), a polyketide, is a microbial secondary metabolite. Sporminarin A can be isolated from the Sporormiella minimoides. Sporminarin A has significant antifungal activity against Aspergillus flavus with an MIC50 of 25  μg/mL. Sporminarin A also has antibacterial activity against Staphylococcus aureus (ATCC 29213) and Candida albicans (ATCC 14053) .
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