1. Search Result
Search Result
Results for "

oleanane saponin

" in MedChemExpress (MCE) Product Catalog:

28

Inhibitors & Agonists

28

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N0819
    Raddeanin A
    1 Publications Verification

    Apoptosis PI3K Akt ERK mTOR Wnt β-catenin Wee1 JNK VEGFR CDK Neurological Disease Inflammation/Immunology Cancer
    Raddeanin A is an oleanane-type triterpenoid saponin with oral activity. Raddeanin A inhibits SRC, mTOR, JNK, VEGFR2, NLRP3 inflammasome, Wnt/β-catenin, Wee1, PI3K/AKT signaling pathway, MAPK/ERK signaling pathway, AR-FL, AR-Vs, and downregulates the expression of p-PI3K and p-AKT. Raddeanin A inhibits osteoclast formation, bone resorption, osteolysis, cancer cell invasion, migration, proliferation, angiogenesis and epithelial-mesenchymal transition, while induces apoptosis, cell cycle arrest, ROS production, immunogenic cell death and dendritic cell maturation. Raddeanin A improves blood-retinal barrier function, alleviates inflammation, regulates the tumor microenvironment, and enhances the activity of anti-PD-1 antibody. Raddeanin A is applicable to the research of breast cancer-associated osteolysis, human osteosarcoma, colorectal cancer, glioblastoma, Alzheimer's disease, cholangiocarcinoma, melanoma, non-small cell lung cancer, castration-resistant prostate cancer and multiple myeloma .
    Raddeanin A
  • HY-N7026
    Celosin I
    1 Publications Verification

    Others Metabolic Disease
    Celosin I, an oleanane-type triterpenoid saponin isolated from the seeds of Celosia argentea L, could be used as chemical markers for the quality control of C. argentea seeds. Celosin I exhibits significant hepatoprotective effect on carbon tetrachloride-induced and N,N-dimethylformamide-induced hepatotoxicity in mice .
    Celosin I
  • HY-N7273

    Apoptosis Cancer
    Soyasaponin III, a monodesmodic oleanane triterpenoid, is one of the main potentially bioactive saponins found in soy (Glycine max) and related products. Soyasaponin III can induce apoptosis in Hep-G2 cells .
    Soyasaponin III
  • HY-N8609

    Others Others
    Uralsaponin C is an analogue of oleanane-type triterpenoid saponin. Uralsaponin C can be isolated from the roots of Glycyrrhiza uralensis Fisch .
    Uralsaponin C
  • HY-N11034

    Others Others
    24-Hydroxy-licorice-saponin A3 is an oleanane-type triterpene saponin (OTS). 24-Hydroxy-licorice-saponin A3 can be isolated from G. uralensis. .
    24-Hydroxy-licorice-saponin A3
  • HY-N11068

    Others Others
    Huzhangoside C is a oleanane-type triterpenoid saponin that can be isolated from the roots of Clematis argentilucida .
    Huzhangoside C
  • HY-N13847

    Bacterial Inflammation/Immunology
    Uralsaponin B is classified as an oleanane-type triterpenoid saponin. Uralsaponin B exhibits potential anti-inflammatory and anti-infective activities.
    Uralsaponin B
  • HY-N9328

    Others Cancer
    Tarasaponin IV, as an oleanane-type triterpene saponin, is isolated from the bark of Aralia elata. Tarasaponin IV can be used for the research of cancer .
    Tarasaponin IV
  • HY-N12584

    Others Others
    Pulchinenoside E4 (compound 2) is an oleanane-type triterpenoidal saponin that can be found in the roots ofPulsatilla chinensis . Pulchinenoside E4 shows cytotoxic activity .
    Pulchinenoside E4
  • HY-N19817

    Biochemical Assay Reagents Others
    Gleditsioside H is an oleanane-type bisdesmosidic saponin that can be isolated from the malformed fruits of Gleditsia sinensis .
    Gleditsioside H
  • HY-N0819R

    Reference Standards Apoptosis PI3K Akt ERK mTOR Wnt β-catenin Wee1 JNK VEGFR CDK Neurological Disease Inflammation/Immunology Cancer
    Raddeanin A (Standard) is the analytical standard of Raddeanin A (HY-N0819). This product is intended for research and analytical applications. Raddeanin A is an oleanane-type triterpenoid saponin with oral activity. Raddeanin A inhibits SRC, mTOR, JNK, VEGFR2, NLRP3 inflammasome, Wnt/β-catenin, Wee1, PI3K/AKT signaling pathway, MAPK/ERK signaling pathway, AR-FL, AR-Vs, and downregulates the expression of p-PI3K and p-AKT. Raddeanin A inhibits osteoclast formation, bone resorption, osteolysis, cancer cell invasion, migration, proliferation, angiogenesis and epithelial-mesenchymal transition, while induces apoptosis, cell cycle arrest, ROS production, immunogenic cell death and dendritic cell maturation. Raddeanin A improves blood-retinal barrier function, alleviates inflammation, regulates the tumor microenvironment, and enhances the activity of anti-PD-1 antibody. Raddeanin A is applicable to the research of breast cancer-associated osteolysis, human osteosarcoma, colorectal cancer, glioblastoma, Alzheimer's disease, cholangiocarcinoma, melanoma, non-small cell lung cancer, castration-resistant prostate cancer and multiple myeloma.
    Raddeanin A (Standard)
  • HY-N19713

    Drug Derivative Others
    Araliasaponin XIV is an oleanane-type triterpene saponin that can be found in the roots of Aralia chinensis .
    Araliasaponin XIV
  • HY-N17243

    Others Others
    Aesculinoside C is an acylated polyhydroxy oleanane-type triterpene saponin that is found in the seeds of Aesculus chinensis .
    Aesculinoside C
  • HY-N11458

    Others Others
    Raddeanoside R16 is an oleanane-type saponin, that can be isolated from the rhizoma of Anemone raddeana .
    Raddeanoside R16
  • HY-N9545

    Others Others
    Talinumoside I is an oleanane-type saponin. Talinumoside I can be isolated from species of the genus Talinum .
    Talinumoside I
  • HY-N18092

    Others Others
    Platycodin C is an oleanane-type oligoglycoside and monoacetylated saponin found in the roots of Platycodon grandiflorum A. DC. (Campanulaceae) .
    Platycodin C
  • HY-N13724

    Others Others
    Stipuleanoside R1 is an oleanane-type saponin that can be isolated from the aerial parts (leaves and stems) of Panax bipinnatifidus .
    Stipuleanoside R1
  • HY-N19858

    Others Cancer
    Millettiasaponin B is an oleanane-type triterpene saponin found in the roots of Millettia speciosa. Millettiasaponin B can be used in leukemia research .
    Millettiasaponin B
  • HY-N16930

    Drug Derivative Others
    Phytolaccagenic acid 28-O-β-D-glucopyranosyl ester is a natural triterpene.
    Phytolaccagenic acid 28-O-β-D-glucopyranosyl ester
  • HY-N17752

    Others Cancer
    Phaseoloideside C is an oleanane-type triterpenoid saponin. Phaseoloideside C can be isolated from the seeds of *Entada phaseoloides*. Phaseoloideside C exhibits no cytotoxicity against hepatocellular carcinoma cells, esophageal carcinoma cells, cervical carcinoma cells, and colon carcinoma cells .
    Phaseoloideside C
  • HY-N19813

    NO Synthase Others
    Flaccidoside VI is an inhibitor of nitric oxide production belonging to oleanane-type triterpenoid saponins. Flaccidoside VI can be isolated from the rhizomes of Anemone flaccida. Flaccidoside VI exhibits significant inhibitory activity against lipopolysaccharide-induced nitric oxide production .
    Flaccidoside VI
  • HY-N19755

    Fungal Infection
    Clemontanoside-C is an oleanane-based triterpenoid saponin and antifungal agent found in the roots of Lepidagathis cuspidata. Clemontanoside-C acts against Aspergillus flavus, Rhizopus stolinifer, Penicillum nodatum, and Aspergillus fumigatus. Clemontanoside-C can be used for the research of fungal infections .
    Clemontanoside-C
  • HY-N19857

    Biochemical Assay Reagents Cardiovascular Disease Metabolic Disease
    Millettiasaponin A is an oleanane-type triterpenoid saponin found in the stems of Derris eriocarpa and roots of Millettia speciosa. Millettiasaponin A is 150 times sweeter than Sucrose (HY-B1779) at 1% concentration. Millettiasaponin A can be used in research on hypertension and obesity. .
    Millettiasaponin A
  • HY-N17751

    Others Cancer
    Phaseoloideside D is an oleanane-type triterpene saponin. Phaseoloideside D can be found in the seeds of *Entada phaseoloides*. Phaseoloideside D exhibits cytotoxicity against esophageal cancer, liver cancer, and cervical cancer cells. Phaseoloideside D can be used in colon cancer research .
    Phaseoloideside D
  • HY-N19794

    Drug Derivative Cardiovascular Disease Metabolic Disease
    Derrisaponin A is an oleanane-type triterpenoid saponin and sweetener found in the stems of Derris eriocarpa, with sweetness intensity approximately 80 times that of Sucrose (HY-B1779) at 1% concentration. Derrisaponin A shows no acute toxic activity. Derrisaponin A can be used for research on hypertension, hyperglycemia, and obesity .
    Derrisaponin A
  • HY-N19793

    Drug Derivative Cardiovascular Disease Metabolic Disease
    Derrisaponin B is an oleanane-type triterpenoid saponin and sweetener found in the stems of Derris eriocarpa How, with sweetness intensity approximately 2 times that of Sucrose (HY-B1779) at 1% concentration. Derrisaponin B exhibits sweet taste activity. Derrisaponin B can be used for research on hypertension, hyperglycemia, and obesity .
    Derrisaponin B
  • HY-N17959

    Others Others
    Vitalboside A is a triterpene found in the stem bark of Albizia gummifera .
    Vitalboside A
  • HY-N19757

    Fungal Infection
    3-O-(2-Acetamido-2-deoxy-β-D-glucopyranosyl) echinocystic acid is an oleanane-type triterpenoid saponin. 3-O-(2-Acetamido-2-deoxy-β-D-glucopyranosyl) echinocystic acid acts as a dermatophyte growth inhibitor with a MIC range of 6.25-25 μg/mL. 3-O-(2-Acetamido-2-deoxy-β-D-glucopyranosyl) echinocystic acid can be used in the research of dermatophyte infections, bacterial infections and yeast infections .
    (3β,16α-Hydroxy)-3-O-(2'acetamido-2'-deoxy-β-D-glucopyranosyl) echinocystic acid

Inquiry Online

Your information is safe with us. * Required Fields.

Salutation

 

Country or Region *

Applicant Name *

 

Organization Name *

Department *

     

Email Address *

 

Product Name *

Cat. No.

 

Requested quantity *

Phone Number *

     

Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent: