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  3. Drug Derivative
  4. Derrisaponin A

Derrisaponin A is an oleanane-type triterpenoid saponin and sweetener found in the stems of Derris eriocarpa, with sweetness intensity approximately 80 times that of Sucrose (HY-B1779) at 1% concentration. Derrisaponin A shows no acute toxic activity. Derrisaponin A can be used for research on hypertension, hyperglycemia, and obesity.

For research use only. We do not sell to patients.

Derrisaponin A

Derrisaponin A Chemical Structure

CAS No. : 1965272-21-2

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Derrisaponin A Related Antibodies

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Description

Derrisaponin A is an oleanane-type triterpenoid saponin and sweetener found in the stems of Derris eriocarpa, with sweetness intensity approximately 80 times that of Sucrose (HY-B1779) at 1% concentration. Derrisaponin A shows no acute toxic activity. Derrisaponin A can be used for research on hypertension, hyperglycemia, and obesity[1].

In Vitro

Derrisaponin A (Compound 2) (2 mg; 2 h) produces D-glucuronic acid (HY-N6612), D-galactose (HY-N0210), L-rhamnose (HY-N1420), and D-glucose (HY-B0389) upon acid hydrolysis[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Derrisaponin A Related Antibodies
In Vivo

Derrisaponin A (Compound 2) (400 mg/kg bw; i.v.; single injection) has a maximum tolerated dose of 400 mg/kg bw in ICR mice when administered as a single intravenous injection, with no persistent acute toxic effects observed over 14 days[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: ICR mice (male and female, 3-4 weeks old, specific pathogen-free)[1]
Dosage: 400 mg/kg bw
Administration: i.v.; single injection
Result: Observed transient diaphragm spasm in one mouse that resolved within 10 minutes post-injection.
Detected no other treatment-related clinical signs of toxicity, mortality, or gross pathological changes to internal organs over the 14-day observation period.
Determined the maximum tolerated dose (MTD) to be 400 mg/kg bw.
Molecular Weight

1177.28

Formula

C56H88O26
CAS No.
SMILES

C[C@]12[C@]3(C([C@@]4([H])[C@@](CC3)([C@@H](C[C@@](C)(C4)C(O)=O)OC(C)=O)C)=CC[C@]1([H])[C@@]5([C@@]([C@](C)([C@H](CC5)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)C(O)=O)O)O)O[C@H]7[C@@H]([C@H]([C@H]([C@H](O7)CO)O)O[C@@H]8O[C@@H]([C@H]([C@@H]([C@H]8O)O)O)CO)O[C@H]9[C@@H]([C@@H]([C@H]([C@@H](O9)C)O)O)O)CO)([H])CC2)C)C
Structure Classification
Initial Source
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
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References
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Derrisaponin A Related Classifications

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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Derrisaponin A1965272-21-2Drug DerivativeDrug derivativeDerris eriocarpaoleanane-type triterpenoid saponinL-rhamnosesweetenerD-galactoseICR miceD-glucuronic acidD-glucoseInhibitorinhibitorinhibit

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