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  3. Millettiasaponin A

Millettiasaponin A is an oleanane-type triterpenoid saponin found in the stems of Derris eriocarpa and roots of Millettia speciosa. Millettiasaponin A is 150 times sweeter than Sucrose (HY-B1779) at 1% concentration. Millettiasaponin A can be used in research on hypertension and obesity..

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Millettiasaponin A

Millettiasaponin A Chemische Struktur

CAS. Nr. : 562070-88-6

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Beschreibung

Millettiasaponin A is an oleanane-type triterpenoid saponin found in the stems of Derris eriocarpa and roots of Millettia speciosa. Millettiasaponin A is 150 times sweeter than Sucrose (HY-B1779) at 1% concentration. Millettiasaponin A can be used in research on hypertension and obesity.[1][2].

In Vitro

Millettiasaponin A (Compound 1) (0.1-50 μg/mL; 72 h) shows no cytotoxicity against human leukemia HL-60 cells at a concentration of 50 μg/mL[2].
Millettiasaponin A (0.1-50 μg/mL; 60 min) does not inhibit leukotriene secretion from rat basophilic leukemia RBL-2H3 cells[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Millettiasaponin A (250 mg/kg; i.v.; single injection) shows no acute toxicity in ICR mice[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: ICR mice (male and female, 3-4 weeks old, specific pathogen-free)[1]
Dosage: 250 mg/kg
Administration: i.v.; single injection
Result: Showed no treatment-related clinical signs of toxicity or mortality over the 14-day observation period.
Revealed no gross pathological changes in all internal organs examined at necropsy.
Molekulargewicht

1015.14

Formel

C50H78O21

CAS. Nr.
SMILES

C[C@]12[C@@](CC=C3[C@]2(CC[C@@]4([C@@]3([H])C[C@](C)(C[C@H]4OC(C)=O)C(O)=O)C)C)([H])[C@@]5([C@@]([C@](C)([C@H](CC5)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)C(O)=O)O)O)O[C@H]7[C@@H]([C@H]([C@H]([C@H](O7)CO)O)O)O[C@H]8[C@@H]([C@@H]([C@H]([C@@H](O8)C)O)O)O)CO)([H])CC1)C

Structure Classification
Initial Source
Versand

Room temperature in continental US; may vary elsewhere.

Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

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Millettiasaponin A
Art. -Nr.:
HY-N19857
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