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Cat. No.: HY-N19857

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Millettiasaponin A

Millettiasaponin A is an oleanane-type triterpenoid saponin found in the stems of Derris eriocarpa and roots of Millettia speciosa. Millettiasaponin A is 150 times sweeter than Sucrose (HY-B1779) at 1% concentration. Millettiasaponin A can be used in research on hypertension and obesity..

For research use only. We do not sell to patients.

CAS No.: 562070-88-6
Formula: C₅₀H₇₈O₂₁
Molecular Weight:1015.14

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Millettiasaponin A Chemical Structure

CAS No.: 562070-88-6

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
- In Vivo
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
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Biological Activity

Description

In Vitro

Millettiasaponin A (Compound 1) (0.1-50 μg/mL; 72 h) shows no cytotoxicity against human leukemia HL-60 cells at a concentration of 50 μg/mL^[2].
Millettiasaponin A (0.1-50 μg/mL; 60 min) does not inhibit leukotriene secretion from rat basophilic leukemia RBL-2H3 cells^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Millettiasaponin A (250 mg/kg; i.v.; single injection) shows no acute toxicity in ICR mice^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:

ICR mice (male and female, 3-4 weeks old, specific pathogen-free)^[1]
Dosage:

250 mg/kg
Administration:

i.v.; single injection
Result:

Showed no treatment-related clinical signs of toxicity or mortality over the 14-day observation period.
Revealed no gross pathological changes in all internal organs examined at necropsy.

Chemical Information

CAS No. 562070-88-6
Molecular Weight 1015.14
Formula C₅₀H₇₈O₂₁
SMILES

C[C@]12[C@@](CC=C3[C@]2(CC[C@@]4([C@@]3([H])C[C@](C)(C[C@H]4OC(C)=O)C(O)=O)C)C)([H])[C@@]5([C@@]([C@](C)([C@H](CC5)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)C(O)=O)O)O)O[C@H]7[C@@H]([C@H]([C@H]([C@H](O7)CO)O)O)O[C@H]8[C@@H]([C@@H]([C@H]([C@@H](O8)C)O)O)O)CO)([H])CC1)C
Structure Classification
- Terpenoids
- Triterpenes
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Zhang HX, et al. New Sweet-Tasting Oleanane-Type Triterpenoid Saponins from "Tugancao" (Derris eriocarpa How). J Agric Food Chem. 2017;65(11):2357-2363. [Content Brief]

[2]. Fujimoto Y, et al. New Oleanane-Type Triterpene Saponins from Millettia speciosa. Heterocycles. 2003 Jan 20;60(3):655-661.

Calculators

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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